TRPC1 / IP3R2
Screening
Validation: In vitro validation
Validation: In vivo validation
Characterization
Functional consequence
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Screening
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| Experimental screening | Non-experimental screening | Reference | |||||||
| TRP channel construct | Interactor source | ||||||||
| TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | ||
| TRPC1 | IP3R2 | Inference | Prediction | 10970773 | |||||
(
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Screening
Validation: In vitro validation
Validation: In vivo validation
Characterization
Functional consequence
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top
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Validation: In vivo validation
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| Assay with endogenous proteins | Assay with overexpressed proteins | Reference | |||||||
| Cell or tissue | Cell or tissue | TRP channel construct | Interactor construct | ||||||
| TRP channel | Interactor | Method | Species | Region | Species | Region | |||
| TRPC1 | IP3R2 | Co-immunoprecipitation | Human platelets | 17681754 | |||||
| TRPC1 | IP3R2 | Co-immunoprecipitation | Human platelets | 11336651 | |||||
| TRPC1 | IP3R2 | Co-immunoprecipitation | Human platelets | 18068335 | |||||
| TRPC1 | IP3R2 | Co-immunoprecipitation | Human platelets | 16870612 | |||||
| TRPC1 | IP3R2 | Co-immunoprecipitation | Human platelets | 18191041 | |||||
| TRPC1 | IP3R2 | Co-immunoprecipitation | Rat astrocyte | 16905188 | |||||
| TRPC1 | IP3R2 | Co-immunoprecipitation | Human platelets | 18249094 | |||||
| TRPC1 | IP3R2 | Co-immunoprecipitation | Human platelets | 15121806 | |||||
| TRPC1 | IP3R2 | Co-immunoprecipitation | Human platelets | 12196544 | |||||
| TRPC1 | IP3R2 | Co-immunoprecipitation | Human platelets | 23228564 | |||||
| TRPC1 | IP3R2 | Co-immunoprecipitation | MEG-01 | 23228564 | |||||
| TRPC1 | IP3R2 | Co-immunoprecipitation | Human platelets | 10970773 | |||||
(
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Screening
Validation: In vitro validation
Validation: In vivo validation
Characterization
Functional consequence
|
top
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Functional consequence
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| TRP channel | Interactor | Method | Post-translational modification | Subcellular trafficking | Activity | Reference | |||||
| TRPC1 | IP3R2 | Calcium measurement | Activation | 12196544 | |||||||
| TRPC1 | IP3R2 | Patch clamp | Activation | 12196544 | |||||||
(
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)




Screening