TRPC5 / TRPC1
Screening
Validation: In vitro validation
Validation: In vivo validation
Characterization
Functional consequence
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Screening
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| Experimental screening | Non-experimental screening | Reference | |||||||
| TRP channel construct | Interactor source | ||||||||
| TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | ||
| TRPC5 | TRPC1 | Inference | Prediction | 11301024 | |||||
(
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Screening
Validation: In vitro validation
Validation: In vivo validation
Characterization
Functional consequence
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Validation: In vivo validation
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| Assay with endogenous proteins | Assay with overexpressed proteins | Reference | |||||||
| Cell or tissue | Cell or tissue | TRP channel construct | Interactor construct | ||||||
| TRP channel | Interactor | Method | Species | Region | Species | Region | |||
| TRPC5 | TRPC1 | Co-immunoprecipitation | Rat brain microsome | 12857742 | |||||
| TRPC5 | TRPC1 | Co-immunoprecipitation | Rat brain microsome | 11301024 | |||||
| TRPC5 | TRPC1 | Co-immunoprecipitation | HEK293 | Mouse | Full-length | Human | Full-length | 11301024 | |
| TRPC5 | TRPC1 | Co-immunoprecipitation | Sf9 | Mouse | Full-length | Human | Full-length | 12377790 | |
| TRPC5 | TRPC1 | Co-immunoprecipitation | Rat brain synaptome | 12377790 | |||||
| TRPC5 | TRPC1 | Co-immunoprecipitation | Rabbit coronary artery | 18356201 | |||||
| TRPC5 | TRPC1 | Co-immunoprecipitation | Rabbit mesenteric artery | 18356201 | |||||
| TRPC5 | TRPC1 | Co-immunoprecipitation | Rabbit portal vein | 18356201 | |||||
| TRPC5 | TRPC1 | Co-immunoprecipitation | Human platelets | 16270640 | |||||
| TRPC5 | TRPC1 | Co-immunoprecipitation | Mouse vascular smooth muscle cell | 21968068 | |||||
| TRPC5 | TRPC1 | Fluorescence resonance energy transfer | HEK293 | Mouse | Full-length | Human | Full-length | 12032305 | |
(
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Screening
Validation: In vitro validation
Validation: In vivo validation
Characterization
Functional consequence
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top
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Functional consequence
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| TRP channel | Interactor | Method | Post-translational modification | Subcellular trafficking | Activity | Reference | |||||
| TRPC5 | TRPC1 | Patch clamp | New channel creation | 12857742 | |||||||
| TRPC5 | TRPC1 | Patch clamp | New channel creation | 11301024 | |||||||
(
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)




Screening