TRPML3 / TRPML1

Interaction: TRPML3Detail / TRPML1Detail
Arrow2 Screening Arrow2 Validation: In vitro validation Arrow2 Validation: In vivo validation Arrow2 Characterization Arrow2 Functional consequence Arrow2 top
Screening Toggle
  Experimental screening Non-experimental screening Reference
TRP channel construct Interactor source
TRP channel Interactor Method Species Region Species Organ/tissue Sample type
TRPML3 TRPML1 Inference Prediction 16606612
(Link: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Arrow2 Screening Arrow2 Validation: In vitro validation Arrow2 Validation: In vivo validation Arrow2 Characterization Arrow2 Functional consequence Arrow2 top
Validation: In vivo validation Toggle
  Assay with endogenous proteins Assay with overexpressed proteins Reference
Cell or tissue Cell or tissue TRP channel construct Interactor construct
TRP channel Interactor Method Species Region Species Region
TRPML3 TRPML1 Co-immunofluorescence staining HEK293 19557826
TRPML3 TRPML1 Co-immunofluorescence staining CHO Human Full-length Human Full-length 19885840
TRPML3 TRPML1 Co-immunoprecipitation HEK293 Human Full-length (mutation in the pore region) Human Full-length (mutation in the pore region) 20736310
TRPML3 TRPML1 Co-immunoprecipitation HEK293 Human Full-length Not specified Full-length 19522758
TRPML3 TRPML1 Co-immunoprecipitation HEK293 19557826
TRPML3 TRPML1 Co-immunoprecipitation CHO Human Full-length Human Full-length 19885840
TRPML3 TRPML1 Fluorescence resonance energy transfer HEK293 Mouse Full-length Human Full-length 16606612
(Link: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Arrow2 Screening Arrow2 Validation: In vitro validation Arrow2 Validation: In vivo validation Arrow2 Characterization Arrow2 Functional consequence Arrow2 top
Functional consequence Toggle
TRP channel Interactor Method Post-translational modification Subcellular trafficking Activity Reference
TRPML3 TRPML1 Co-immunofluorescence staining Increase in lysosomal membrane level 16606612
TRPML3 TRPML1 Patch clamp New channel creation 19885840
(Link: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
TRP / Interactor

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