TRPML3 / TRPML2
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Screening
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Experimental screening | Non-experimental screening | Reference | |||||||
TRP channel construct | Interactor source | ||||||||
TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | ||
TRPML3 | TRPML2 | Inference | Prediction | 16606612 |
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click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)

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Validation: In vivo validation
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Assay with endogenous proteins | Assay with overexpressed proteins | Reference | |||||||
Cell or tissue | Cell or tissue | TRP channel construct | Interactor construct | ||||||
TRP channel | Interactor | Method | Species | Region | Species | Region | |||
TRPML3 | TRPML2 | Co-immunofluorescence staining | HEK293 | 19557826 | |||||
TRPML3 | TRPML2 | Co-immunoprecipitation | HEK293 | 19557826 | |||||
TRPML3 | TRPML2 | Co-immunoprecipitation | HEK293 | Human | Full-length (mutation in the pore region) | Human | Full-length (mutation in the pore region) | 20736310 | |
TRPML3 | TRPML2 | Fluorescence resonance energy transfer | HEK293 | Not specified | Full-length | Not specified | Full-length | 23469151 | |
TRPML3 | TRPML2 | Fluorescence resonance energy transfer | HEK293 | Mouse | Full-length | Human | Full-length | 16606612 |
(
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click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)

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Functional consequence
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TRP channel | Interactor | Method | Post-translational modification | Subcellular trafficking | Activity | Reference | |||||
TRPML3 | TRPML2 | Co-immunofluorescence staining | Increase in lysosomal membrane level | 16606612 |
(
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
