TRPP1 / TRPC1

Interaction: TRPP1Detail / TRPC1Detail
Arrow2 Screening Arrow2 Validation: In vitro validation Arrow2 Validation: In vivo validation Arrow2 Characterization Arrow2 Functional consequence Arrow2 top
Screening Toggle
  Experimental screening Non-experimental screening Reference
TRP channel construct Interactor source
TRP channel Interactor Method Species Region Species Organ/tissue Sample type
TRPP1 TRPC1 Inference Prediction 10097141
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Arrow2 Screening Arrow2 Validation: In vitro validation Arrow2 Validation: In vivo validation Arrow2 Characterization Arrow2 Functional consequence Arrow2 top
Validation: In vitro validation Toggle
  Assay with recombinant proteins Reference
TRP channel construct Interactor construct
TRP channel Interactor Method Species Region Expression system Species Region Expression system
TRPP1 TRPC1 Fusion protein-pull down assay Human 680-968 In vitro translation Human 662-750 E. coli 10097141
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Arrow2 Screening Arrow2 Validation: In vitro validation Arrow2 Validation: In vivo validation Arrow2 Characterization Arrow2 Functional consequence Arrow2 top
Validation: In vivo validation Toggle
  Assay with endogenous proteins Assay with overexpressed proteins Reference
Cell or tissue Cell or tissue TRP channel construct Interactor construct
TRP channel Interactor Method Species Region Species Region
TRPP1 TRPC1 Co-immunofluorescence staining HEK293 tsA 201 Human Full-length Human Full-length 19850920
TRPP1 TRPC1 Co-immunofluorescence staining mIMCD-3 18323855
TRPP1 TRPC1 Co-immunofluorescence staining HEK293T Human Full-length Human Full-length 10097141
TRPP1 TRPC1 Co-immunoprecipitation HEK293T Not specified Not specified Human Full-length 14530267
TRPP1 TRPC1 Co-immunoprecipitation Human glomerular mesangial cell Not used Human Full-length 18256307
TRPP1 TRPC1 Co-immunoprecipitation HEK293 Human Full-length Mouse Full-length 19812035
TRPP1 TRPC1 Co-immunoprecipitation HEK293 tsA 201 Human Full-length Human Full-length 19850920
TRPP1 TRPC1 Co-immunoprecipitation Rat kidney tissue 18323855
TRPP1 TRPC1 Co-immunoprecipitation HEK293 tsA 201 Human Full-length Human Full-length 20682256
TRPP1 TRPC1 Co-immunoprecipitation HEK293T Human Full-length Human Full-length 10097141
(Link: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Arrow2 Screening Arrow2 Validation: In vitro validation Arrow2 Validation: In vivo validation Arrow2 Characterization Arrow2 Functional consequence Arrow2 top
Characterization Toggle
  Binding region mapping Stoichiometry Affinity (Kd) Reference
TRP channel Interactor
TRP channel Interactor Method Species Region Species Region
TRPP1 TRPC1 Atomic force microscopy(AFM) analysis 2:2 19850920
TRPP1 TRPC1 Atomic force microscopy(AFM) analysis 2:2 19193631
TRPP1 TRPC1 Co-immunoprecipitation Human 1-643 Human Not determined 10097141
TRPP1 TRPC1 Co-immunoprecipitation Human 679-968 Human Not determined 10097141
TRPP1 TRPC1 Yeast two-hybrid Human 822-895 Human 639-750 10097141
(Link: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Arrow2 Screening Arrow2 Validation: In vitro validation Arrow2 Validation: In vivo validation Arrow2 Characterization Arrow2 Functional consequence Arrow2 top
Functional consequence Toggle
TRP channel Interactor Method Post-translational modification Subcellular trafficking Activity Reference
TRPP1 TRPC1 Patch clamp New channel creation 18323855
(Link: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
TRP / Interactor

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