TRPP2 / PKD1L3/Polycystin-1L3

Interaction: TRPP2Detail / PKD1L3/Polycystin-1L3Detail
Screening Toggle
  Experimental screening Non-experimental screening Reference
TRP channel construct Interactor source
TRP channel Interactor Method Species Region Species Organ/tissue Sample type
TRPP2 PKD1L3/Polycystin-1L3 Inference Prediction 16891422
(Link: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Validation: In vivo validation Toggle
  Assay with endogenous proteins Assay with overexpressed proteins Reference
Cell or tissue Cell or tissue TRP channel construct Interactor construct
TRP channel Interactor Method Species Region Species Region
TRPP2 PKD1L3/Polycystin-1L3 Co-immunofluorescence staining Mouse taste cell 16891422
TRPP2 PKD1L3/Polycystin-1L3 Co-immunoprecipitation Xenopus oocyte Human Full-length Human Full-length 23212381
TRPP2 PKD1L3/Polycystin-1L3 Co-immunoprecipitation HEK293T Mouse Full-length Mouse Full-length 18535624
TRPP2 PKD1L3/Polycystin-1L3 Co-immunoprecipitation HEK293T Mouse Full-length Mouse Full-length 16891422
TRPP2 PKD1L3/Polycystin-1L3 Co-immunoprecipitation HEK293T Mouse Full-length Mouse Full-length 20538909
(Link: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Characterization Toggle
  Binding region mapping Stoichiometry Affinity (Kd) Reference
TRP channel Interactor
TRP channel Interactor Method Species Region Species Region
TRPP2 PKD1L3/Polycystin-1L3 Co-immunoprecipitation Mouse Full-length Mouse 1594-2151 16891422
TRPP2 PKD1L3/Polycystin-1L3 Co-immunoprecipitation Mouse Not determined Mouse 1896-2040 20538909
TRPP2 PKD1L3/Polycystin-1L3 Single-molecule photobleaching 3:1 23212381
(Link: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Functional consequence Toggle
TRP channel Interactor Method Post-translational modification Subcellular trafficking Activity Reference
TRPP2 PKD1L3/Polycystin-1L3 Co-immunofluorescence staining Increase in plasma membrane level 20538909
TRPP2 PKD1L3/Polycystin-1L3 Patch clamp New channel creation 23212381
TRPP2 PKD1L3/Polycystin-1L3 Patch clamp New channel creation 18535624
(Link: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
TRP / Interactor

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