TRPV2 / RGA/RAG1AP1
Interaction:
TRPV2
/
RGA/RAG1AP1
/
RGA/RAG1AP1
 Screening
Validation: In vitro validation
Validation: In vivo validation
Characterization
Functional consequence
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Screening
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| Experimental screening | Non-experimental screening | Reference | |||||||
| TRP channel construct | Interactor source | ||||||||
| TRP channel | Interactor | Method | Species | Region | Species | Organ/tissue | Sample type | ||
| TRPV2 | RGA/RAG1AP1 | Yeast two-hybrid | Rat | N-terminus | Rat | Brain | cDNA library | 14991772 | |
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:
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:
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|
Screening
Validation: In vitro validation
Validation: In vivo validation
Characterization
Functional consequence
|
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|
| Validation: In vivo validation
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| Assay with endogenous proteins | Assay with overexpressed proteins | Reference | |||||||
| Cell or tissue | Cell or tissue | TRP channel construct | Interactor construct | ||||||
| TRP channel | Interactor | Method | Species | Region | Species | Region | |||
| TRPV2 | RGA/RAG1AP1 | Co-immunofluorescence staining | HEK293 | Rat | Full-length | Mouse | Full-length | 14991772 | |
| TRPV2 | RGA/RAG1AP1 | Co-immunoprecipitation | RBL-2H3 | Not used | Mouse | Full-length | 14991772 | ||
| TRPV2 | RGA/RAG1AP1 | Co-immunoprecipitation | HEK293 | Rat | Full-length | Mouse | Full-length | 14991772 | |
| TRPV2 | RGA/RAG1AP1 | Co-immunoprecipitation | RBL-2H3 | 15547947 | |||||
| TRPV2 | RGA/RAG1AP1 | Co-immunoprecipitation | HEK293 | Rat | Full-length | Human | Full-length | 15547947 | |
(:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
|
Screening
Validation: In vitro validation
Validation: In vivo validation
Characterization
Functional consequence
|
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|
| Functional consequence
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| TRP channel | Interactor | Method | Post-translational modification | Subcellular trafficking | Activity | Reference | |||||
| TRPV2 | RGA/RAG1AP1 | Cell surface biotinylation | Increase in plasma membrane level | 15547947 | |||||||
(:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
:
click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)