Myosin-5a / TRP channels

Name: Unconventional myosin-Va (Myosin-5a)
Official Symbol: MYO5A provided by HGNC
Function:
Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. May also be required for some polarization process involved in dendrite formation.
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt) Nucleic Acids Res. 40: D71-D75 (2012).
Species External DB Questionmark
Entrez Gene UniprotKB DIP IntAct MINT BioGRID STRING IUPHAR-DB KEGG OMIM
Human
Seq		 4644External Q9Y4I1External DIP-44243NExternal Q9Y4I1External MINT-3388025External 110728External Q9Y4I1External   hsa:4644External 160777External
Mouse
Seq		 17918External Q99104External DIP-29542NExternal Q99104External MINT-243234External 201666External Q99104External   mmu:17918External  
Rat
Seq		 25017External Q9QYF3External DIP-57326NExternal   MINT-7138773External 247098External Q9QYF3External   rno:25017External  
PPI pairs:
Biological Process:
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
Disease:
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
Arrow2 Screening Arrow2 Validation: In vitro validation Arrow2 Validation: In vivo validation Arrow2 Characterization Arrow2 Functional consequence Arrow2 top
Screening Toggle
  Experimental screening Non-experimental screening Reference
TRP channel construct Interactor source
TRP channel Interactor Method Species Region Species Organ/tissue Sample type
TRPC5 Link Myosin-5a Affinity purification-mass spectrometry Endogenous protein Rat Brain Cerebral cortex lysates 16025302
(Link: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
TRP / Interactor

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