Nipsnap1 / TRP channels

Name: Protein NipSnap homolog 1 (Nipsnap1)
Official Symbol: NIPSNAP1 provided by HGNC
Function:
Source: Reorganizing the protein space at the Universal Protein Resource (UniProt) Nucleic Acids Res. 40: D71-D75 (2012).
Species External DB Questionmark
Entrez Gene UniprotKB DIP IntAct MINT BioGRID STRING IUPHAR-DB KEGG OMIM
Human
Seq
8508External Q9BPW8External DIP-33563NExternal Q9BPW8External MINT-1405060External 114080External Q9BPW8External   hsa:8508External 603249External
Mouse
Seq
18082External O55125External DIP-32183NExternal O55125External MINT-1859805External 201774External O55125External   mmu:18082External  
Rat
Seq
360971External Q5EBA4External DIP-37126NExternal Q5EBA4External   262337External Q5EBA4External   rno:360971External  
PPI pairs:
Biological Process: No information in Gene Ontology
Source: The Gene Ontology Consortium. Gene ontology: tool for the unification of biology. Nat. Genet.. May 2000;25(1):25-9.
World Wide Web URL: http://www.geneontology.org/
Disease: No information in OMIM
Source: Online Mendelian Inheritance in Man, OMIM®. McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University (Baltimore, MD), May, 2012.
World Wide Web URL: http://omim.org/
Screening Toggle
  Experimental screening Non-experimental screening Reference
TRP channel construct Interactor source
TRP channel Interactor Method Species Region Species Organ/tissue Sample type
TRPV5 Link Nipsnap1 Inference Prediction 18392847
TRPV6 Link Nipsnap1 Inference Prediction 18392847
(Link: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Validation: In vitro validation Toggle
  Assay with recombinant proteins Reference
TRP channel construct Interactor construct
TRP channel Interactor Method Species Region Expression system Species Region Expression system
TRPV6 Link Nipsnap1 Fusion protein-pull down assay Mouse 577-607 E. coli Not specified Full-length E. coli 18392847
(Link: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Validation: In vivo validation Toggle
  Assay with endogenous proteins Assay with overexpressed proteins Reference
Cell or tissue Cell or tissue TRP channel construct Interactor construct
TRP channel Interactor Method Species Region Species Region
TRPV5 Link Nipsnap1 Co-immunoprecipitation HEK293 Rabbit Full-length Not specified Full-length 18392847
TRPV6 Link Nipsnap1 Co-immunoprecipitation HEK293 Mouse Full-length Not specified Full-length 18392847
(Link: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Characterization Toggle
  Binding region mapping Stoichiometry Affinity (Kd) Reference
TRP channel Interactor
TRP channel Interactor Method Species Region Species Region
TRPV6 Link Nipsnap1 Fusion protein-pull down assay Mouse 83-118 Not specified Not determined 18392847
(Link: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
Functional consequence Toggle
TRP channel Interactor Method Post-translational modification Subcellular trafficking Activity Reference
TRPV6 Link Nipsnap1 Patch clamp Inhibition 18392847
(Link: click the arrow icon to show interactions only between the corresponding TRP channel and the interactor)
TRP / Interactor

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