Curated Publications

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PMID Title Authors Journal Year
24269608 The TRPM8 channel forms a complex with the 5-HT1B receptor and phospholipase D that amplifies its reversal of pain hypersensitivity. External Vinuela-Fernandez, I., Sun, L., Jerina, H., Curtis, J., Allchorne, A., Gooding, H., Rosie, R., Holland, P., Tas, B., Mitchell, R., Fleetwood-Walker, S. Neuropharmacology 2014
24157948 Piezo1-dependent stretch-activated channels are inhibited by Polycystin-2 in renal tubular epithelial cells. External Peyronnet, R., Martins, J. R., Duprat, F., Demolombe, S., Arhatte, M., Jodar, M., Tauc, M., Duranton, C., Paulais, M., Teulon, J., Honore, E., Patel, A. EMBO Rep 2013
24147119 TRPV1 channels are functionally coupled with BK(mSlo1) channels in rat dorsal root ganglion (DRG) neurons. External Wu, Y., Liu, Y., Hou, P., Yan, Z., Kong, W., Liu, B., Li, X., Yao, J., Zhang, Y., Qin, F., Ding, J. PLoS One 2013
24114537 Orphan receptor GPR179 forms macromolecular complexes with components of metabotropic signaling cascade in retina ON-bipolar neurons. External Orlandi, C., Cao, Y., Martemyanov, K. A. Invest Ophthalmol Vis Sci 2013
24114458 Inhibition of the Sur1-Trpm4 channel reduces neuroinflammation and cognitive impairment in subarachnoid hemorrhage. External Tosun, C., Kurland, D. B., Mehta, R., Castellani, R. J., deJong, J. L., Kwon, M. S., Woo, S. K., Gerzanich, V., Simard, J. M. Stroke 2013
24036102 Identification of voltage-gated K(+) channel beta 2 (Kvbeta2) subunit as a novel interaction partner of the pain transducer Transient Receptor Potential Vanilloid 1 channel (TRPV1). External Bavassano, C., Marvaldi, L., Langeslag, M., Sarg, B., Lindner, H., Klimaschewski, L., Kress, M., Ferrer-Montiel, A., Knaus, H. G. Biochim Biophys Acta 2013
24022404 Myristoylated alanine-rich C kinase substrate coordinates native TRPC1 channel activation by phosphatidylinositol 4,5-bisphosphate and protein kinase C in vascular smooth muscle. External Shi, J., Birnbaumer, L., Large, W. A., Albert, A. P. FASEB J 2014
24011658 Activation of TRPC4beta by Galphai subunit increases Ca2+ selectivity and controls neurite morphogenesis in cultured hippocampal neuron. External Jeon, J. P., Roh, S. E., Wie, J., Kim, J., Kim, H., Lee, K. P., Yang, D., Jeon, J. H., Cho, N. H., Kim, I. G., Kang, D. E., Kim, H. J., So, I. Cell Calcium 2013
23994313 Transient receptor potential ankyrin-1 (TRPA1) modulates store-operated Ca(2+) entry by regulation of STIM1-Orai1 association. External Albarran, L., Lopez, J. J., Dionisio, N., Smani, T., Salido, G. M., Rosado, J. A. Biochim Biophys Acta 2013
23977387 TRPP2 and TRPV4 form an EGF-activated calcium permeable channel at the apical membrane of renal collecting duct cells. External Zhang, Z. R., Chu, W. F., Song, B., Gooz, M., Zhang, J. N., Yu, C. J., Jiang, S., Baldys, A., Gooz, P., Steele, S., Owsianik, G., Nilius, B., Komlosi, P., Bell, P. D. PLoS One 2013
23911290 Opiates modulate thermosensation by internalizing cold receptor TRPM8. External Shapovalov, G., Gkika, D., Devilliers, M., Kondratskyi, A., Gordienko, D., Busserolles, J., Bokhobza, A., Eschalier, A., Skryma, R., Prevarskaya, N. Cell Rep 2013
23747339 Post-translational loss of renal TRPV5 calcium channel expression, Ca(2+) wasting, and bone loss in experimental colitis. External Radhakrishnan, V. M., Ramalingam, R., Larmonier, C. B., Thurston, R. D., Laubitz, D., Midura-Kiela, M. T., McFadden, R. M., Kuro-O, M., Kiela, P. R., Ghishan, F. K. Gastroenterology 2013
23699529 Mapping the binding site of TRPV1 on AKAP79: implications for inflammatory hyperalgesia. External Btesh, J., Fischer, M. J., Stott, K., McNaughton, P. A. J Neurosci 2013
23686296 Functional transient receptor potential canonical type 1 channels in human atrial myocytes. External Zhang, Y. H., Wu, H. J., Che, H., Sun, H. Y., Cheng, L. C., Li, X., Au, W. K., Tse, H. F., Li, G. R. Pflugers Arch 2013
23671622 Characterization of the S100A1 protein binding site on TRPC6 C-terminus. External Bily, J., Grycova, L., Holendova, B., Jirku, M., Janouskova, H., Bousova, K., Teisinger, J. PLoS One 2013
23645677 Gain-of-function mutations in transient receptor potential C6 (TRPC6) activate extracellular signal-regulated kinases 1/2 (ERK1/2). External Chiluiza, D., Krishna, S., Schumacher, V. A., Schlondorff, J. J Biol Chem 2013
23616546 Disrupting sensitization of transient receptor potential vanilloid subtype 1 inhibits inflammatory hyperalgesia. External Fischer, M. J., Btesh, J., McNaughton, P. A. J Neurosci 2013
23508958 Excitation and modulation of TRPA1, TRPV1, and TRPM8 channel-expressing sensory neurons by the pruritogen chloroquine. External Than, J. Y., Li, L., Hasan, R., Zhang, X. J Biol Chem 2013
23469151 A novel ion channel formed by interaction of TRPML3 with TRPV5. External Guo, Z., Grimm, C., Becker, L., Ricci, A. J., Heller, S. PLoS One 2013
23418601 Systematic screens for proteins that interact with the mucolipidosis type IV protein TRPML1. External Spooner, E., McLaughlin, B. M., Lepow, T., Durns, T. A., Randall, J., Upchurch, C., Miller, K., Campbell, E. M., Fares, H. PLoS One 2013
23395841 The polybasic lysine-rich domain of plasma membrane-resident STIM1 is essential for the modulation of store-operated divalent cation entry by extracellular calcium. External Jardin, I., Dionisio, N., Frischauf, I., Berna-Erro, A., Woodard, G. E., Lopez, J. J., Salido, G. M., Rosado, J. A. Cell Signal 2013
23390129 Hyperphosphorylation of polycystin-2 at a critical residue in disease reveals an essential role for polycystin-1-regulated dephosphorylation. External Streets, A. J., Wessely, O., Peters, D. J., Ong, A. C. Hum Mol Genet 2013
23375350 Regulation of store-operated calcium entry by FK506-binding immunophilins. External Kadeba, P. I., Vasauskas, A. A., Chen, H., Wu, S., Scammell, J. G., Cioffi, D. L. Cell Calcium 2013
23360390 Phosphorylation regulates TRPV1 association with beta-arrestin-2. External Por, E. D., Gomez, R., Akopian, A. N., Jeske, N. A. Biochem J 2013
23345400 Occludin is required for TRPV1-modulated paracellular permeability in the submandibular gland. External Cong, X., Zhang, Y., Yang, N. Y., Li, J., Ding, C., Ding, Q. W., Su, Y. C., Mei, M., Guo, X. H., Wu, L. L., Yu, G. Y. J Cell Sci 2013
23264624 Scaffolding by A-kinase anchoring protein enhances functional coupling between adenylyl cyclase and TRPV1 channel. External Efendiev, R., Bavencoffe, A., Hu, H., Zhu, M. X., Dessauer, C. W. J Biol Chem 2013
23255597 The sulfonylurea receptor 1 (Sur1)-transient receptor potential melastatin 4 (Trpm4) channel. External Woo, S. K., Kwon, M. S., Ivanov, A., Gerzanich, V., Simard, J. M. J Biol Chem 2013
23228564 FKBP52 is involved in the regulation of SOCE channels in the human platelets and MEG 01 cells. External Lopez, E., Berna-Erro, A., Salido, G. M., Rosado, J. A., Redondo, P. C. Biochim Biophys Acta 2013
23212381 Molecular mechanism of the assembly of an acid-sensing receptor ion channel complex. External Yu, Y., Ulbrich, M. H., Li, M. H., Dobbins, S., Zhang, W. K., Tong, L., Isacoff, E. Y., Yang, J. Nat Commun 2012
23171048 SNF8, a member of the ESCRT-II complex, interacts with TRPC6 and enhances its channel activity. External Carrasquillo, R., Tian, D., Krishna, S., Pollak, M. R., Greka, A., Schlondorff, J. BMC Cell Biol 2012
23159249 Recurrent de novo mutations in PACS1 cause defective cranial-neural-crest migration and define a recognizable intellectual-disability syndrome. External Schuurs-Hoeijmakers, J. H., Oh, E. C., Vissers, L. E., Swinkels, M. E., Gilissen, C., Willemsen, M. A., Holvoet, M., Steehouwer, M., Veltman, J. A., de Vries, B. B., van Bokhoven, H., de Brouwer, A. P., Katsanis, N., Devriendt, K., Brunner, H. G. Am J Hum Genet 2012
23142606 Cannabinoid receptor 1 suppresses transient receptor potential vanilloid 1-induced inflammatory responses to corneal injury. External Yang, Y., Yang, H., Wang, Z., Varadaraj, K., Kumari, S. S., Mergler, S., Okada, Y., Saika, S., Kingsley, P. J., Marnett, L. J., Reinach, P. S. Cell Signal 2013
23140583 Regulation of calcium influx and signaling pathway in cancer cells via TRPV6-Numb1 interaction. External Kim, S. Y., Yang, D., Myeong, J., Ha, K., Kim, S. H., Park, E. J., Kim, I. G., Cho, N. H., Lee, K. P., Jeon, J. H., So, I. Cell Calcium 2013
23119017 Integrative binding sites within intracellular termini of TRPV1 receptor. External Grycova, L., Holendova, B., Bumba, L., Bily, J., Jirku, M., Lansky, Z., Teisinger, J. PLoS One 2012
23068106 Different binding property of STIM1 and its novel splice variant STIM1L to Orai1, TRPC3, and TRPC6 channels. External Horinouchi, T., Higashi, T., Higa, T., Terada, K., Mai, Y., Aoyagi, H., Hatate, C., Nepal, P., Horiguchi, M., Harada, T., Miwa, S. Biochem Biophys Res Commun 2012
23045459 An elevation in physical coupling of type 1 inositol 1,4,5-trisphosphate (IP3) receptors to transient receptor potential 3 (TRPC3) channels constricts mesenteric arteries in genetic hypertension. External Adebiyi, A., Thomas-Gatewood, C. M., Leo, M. D., Kidd, M. W., Neeb, Z. P., Jaggar, J. H. Hypertension 2012
23034388 TRPC1 and Orai1 interact with STIM1 and mediate capacitative Ca(2+) entry caused by acute hypoxia in mouse pulmonary arterial smooth muscle cells. External Ng, L. C., O'Neill, K. G., French, D., Airey, J. A., Singer, C. A., Tian, H., Shen, X. M., Hume, J. R. Am J Physiol Cell Physiol 2012
22952227 beta-Arrestin-2 desensitizes the transient receptor potential vanilloid 1 (TRPV1) channel. External Por, E. D., Bierbower, S. M., Berg, K. A., Gomez, R., Akopian, A. N., Wetsel, W. C., Jeske, N. A. J Biol Chem 2012
22932896 Canonical transient receptor potential (TRPC) 1 acts as a negative regulator for vanilloid TRPV6-mediated Ca2+ influx. External Schindl, R., Fritsch, R., Jardin, I., Frischauf, I., Kahr, H., Muik, M., Riedl, M. C., Groschner, K., Romanin, C. J Biol Chem 2012
22789851 Activation of NMDA receptors leads to phosphorylation of TRPV1 S800 by protein kinase C and A-Kinase anchoring protein 150 in rat trigeminal ganglia. External Lee, J., Chung, M. K., Ro, J. Y. Biochem Biophys Res Commun 2012
22778254 Extracellular Ca(2+) sensing in salivary ductal cells. External Bandyopadhyay, B. C., Swaim, W. D., Sarkar, A., Liu, X., Ambudkar, I. S. J Biol Chem 2012
22759789 Identification of Ser/Thr phosphorylation sites in the C2-domain of phospholipase C gamma2 (PLCgamma2) using TRPM7-kinase. External Deason-Towne, F., Perraud, A. L., Schmitz, C. Cell Signal 2012
22750945 Direct inhibition of the cold-activated TRPM8 ion channel by Galphaq. External Zhang, X., Mak, S., Li, L., Parra, A., Denlinger, B., Belmonte, C., McNaughton, P. A. Nat Cell Biol 2012
22640869 Capacitative and non-capacitative signaling complexes in human platelets. External Berna-Erro, A., Galan, C., Dionisio, N., Gomez, L. J., Salido, G. M., Rosado, J. A. Biochim Biophys Acta 2012
22609428 Functional interactions between NMDA receptors and TRPV1 in trigeminal sensory neurons mediate mechanical hyperalgesia in the rat masseter muscle. External Lee, J., Saloman, J. L., Weiland, G., Auh, Q. S., Chung, M. K., Ro, J. Y. Pain 2012
22592407 Polyamines regulate intestinal epithelial restitution through TRPC1-mediated Ca(2)+ signaling by differentially modulating STIM1 and STIM2. External Rao, J. N., Rathor, N., Zhuang, R., Zou, T., Liu, L., Xiao, L., Turner, D. J., Wang, J. Y. Am J Physiol Cell Physiol 2012
22534489 Orai1 determines calcium selectivity of an endogenous TRPC heterotetramer channel. External Cioffi, D. L., Wu, S., Chen, H., Alexeyev, M., St Croix, C. M., Pitt, B. R., Uhlig, S., Stevens, T. Circ Res 2012
22518003 Protein kinase G inhibits flow-induced Ca2+ entry into collecting duct cells. External Du, J., Wong, W. Y., Sun, L., Huang, Y., Yao, X. J Am Soc Nephrol 2012
22506990 Homers regulate calcium entry and aggregation in human platelets: a role for Homers in the association between STIM1 and Orai1. External Jardin, I., Albarran, L., Bermejo, N., Salido, G. M., Rosado, J. A. Biochem J 2012
22492541 Calcium/calmodulin-signaling supports TRPV4 activation in osteoclasts and regulates bone mass. External Masuyama, R., Mizuno, A., Komori, H., Kajiya, H., Uekawa, A., Kitaura, H., Okabe, K., Ohyama, K., Komori, T. J Bone Miner Res 2012
22460725 The TRPM8 ion channel comprises direct Gq protein-activating capacity. External Klasen, K., Hollatz, D., Zielke, S., Gisselmann, G., Hatt, H., Wetzel, C. H. Pflugers Arch 2012
22457348 Selective Galphai subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels. External Jeon, J. P., Hong, C., Park, E. J., Jeon, J. H., Cho, N. H., Kim, I. G., Choe, H., Muallem, S., Kim, H. J., So, I. J Biol Chem 2012
22451679 Transforming growth factor-beta1 regulates Cdk5 activity in primary sensory neurons. External Utreras, E., Keller, J., Terse, A., Prochazkova, M., Iadarola, M. J., Kulkarni, A. B. J Biol Chem 2012
22451665 Calmodulin and S100A1 protein interact with N terminus of TRPM3 channel. External Holakovska, B., Grycova, L., Jirku, M., Sulc, M., Bumba, L., Teisinger, J. J Biol Chem 2012
22451268 Implication of AMP-activated protein kinase in transient receptor potential vanilloid type 1-mediated activation of endothelial nitric oxide synthase. External Ching, L. C., Chen, C. Y., Su, K. H., Hou, H. H., Shyue, S. K., Kou, Y. R., Lee, T. S. Mol Med 2012
22446186 Neurotoxin-induced ER stress in mouse dopaminergic neurons involves downregulation of TRPC1 and inhibition of AKT/mTOR signaling. External Selvaraj, S., Sun, Y., Watt, J. A., Wang, S., Lei, S., Birnbaumer, L., Singh, B. B. J Clin Invest 2012
22374181 Importance of transient receptor potential vanilloid 4 (TRPV4) in epidermal barrier function in human skin keratinocytes. External Kida, N., Sokabe, T., Kashio, M., Haruna, K., Mizuno, Y., Suga, Y., Nishikawa, K., Kanamaru, A., Hongo, M., Oba, A., Tominaga, M. Pflugers Arch 2012
22309793 Interaction of transient receptor potential vanilloid 4 with annexin A2 and tubulin beta 5. External Huai, J., Zhang, Y., Liu, Q. M., Ge, H. Y., Arendt-Nielsen, L., Jiang, H., Yue, S. W. Neurosci Lett 2012
22262838 Intact microtubules preserve transient receptor potential vanilloid 1 (TRPV1) functionality through receptor binding. External Storti, B., Bizzarri, R., Cardarelli, F., Beltram, F. J Biol Chem 2012
22226147 The juvenile myoclonic epilepsy-related protein EFHC1 interacts with the redox-sensitive TRPM2 channel linked to cell death. External Katano, M., Numata, T., Aguan, K., Hara, Y., Kiyonaka, S., Yamamoto, S., Miki, T., Sawamura, S., Suzuki, T., Yamakawa, K., Mori, Y. Cell Calcium 2012
22210847 The Ca(2+) sensor stromal interaction molecule 1 (STIM1) is necessary and sufficient for the store-operated Ca(2+) entry function of transient receptor potential canonical (TRPC) 1 and 4 channels in endothelial cells. External Sundivakkam, P. C., Freichel, M., Singh, V., Yuan, J. P., Vogel, S. M., Flockerzi, V., Malik, A. B., Tiruppathi, C. Mol Pharmacol 2012
22201561 Opposite regulatory effects of TRPC1 and TRPC5 on neurite outgrowth in PC12 cells. External Heo, D. K., Chung, W. Y., Park, H. W., Yuan, J. P., Lee, M. G., Kim, J. Y. Cell Signal 2012
22180838 Phosphatidylinositol 4,5-bisphosphate (PIP(2)) controls magnesium gatekeeper TRPM6 activity. External Xie, J., Sun, B., Du, J., Yang, W., Chen, H. C., Overton, J. D., Runnels, L. W., Yue, L. Sci Rep 2011
22174419 Receptor for activated C kinase 1 (RACK1) inhibits function of transient receptor potential (TRP)-type channel Pkd2L1 through physical interaction. External Yang, J., Wang, Q., Zheng, W., Tuli, J., Li, Q., Wu, Y., Hussein, S., Dai, X. Q., Shafiei, S., Li, X. G., Shen, P. Y., Tu, J. C., Chen, X. Z. J Biol Chem 2012
22155451 The proteoglycan syndecan 4 regulates transient receptor potential canonical 6 channels via RhoA/Rho-associated protein kinase signaling. External Liu, Y., Echtermeyer, F., Thilo, F., Theilmeier, G., Schmidt, A., Schulein, R., Jensen, B. L., Loddenkemper, C., Jankowski, V., Marcussen, N., Gollasch, M., Arendshorst, W. J., Tepel, M. Arterioscler Thromb Vasc Biol 2012
22144671 Heteromeric canonical transient receptor potential 1 and 4 channels play a critical role in epileptiform burst firing and seizure-induced neurodegeneration. External Phelan, K. D., Mock, M. M., Kretz, O., Shwe, U. T., Kozhemyakin, M., Greenfield, L. J., Dietrich, A., Birnbaumer, L., Freichel, M., Flockerzi, V., Zheng, F. Mol Pharmacol 2012
22135323 A TRPC5-regulated calcium signaling pathway controls dendrite patterning in the mammalian brain. External Puram, S. V., Riccio, A., Koirala, S., Ikeuchi, Y., Kim, A. H., Corfas, G., Bonni, A. Genes Dev 2011
22101010 Phosphorylation on the Ser 824 residue of TRPV4 prefers to bind with F-actin than with microtubules to expand the cell surface area. External Shin, S. H., Lee, E. J., Hyun, S., Chun, J., Kim, Y., Kang, S. S. Cell Signal 2012
22088247 [Impact of stromal interaction molecule 1 silencing on cell cycle of endothelial progenitor cells]. External Kuang, C. Y., Huang, L., Yu, Y., Deng, M. Y., Wang, K., Qian, D. H. Zhonghua Xin Xue Guan Bing Za Zhi 2011
22027011 A cardiac pathway of cyclic GMP-independent signaling of guanylyl cyclase A, the receptor for atrial natriuretic peptide. External Klaiber, M., Dankworth, B., Kruse, M., Hartmann, M., Nikolaev, V. O., Yang, R. B., Volker, K., Gassner, B., Oberwinkler, H., Feil, R., Freichel, M., Groschner, K., Skryabin, B. V., Frantz, S., Birnbaumer, L., Pongs, O., Kuhn, M. Proc Natl Acad Sci U S A 2011
22001259 Adenylate cyclase/cAMP/protein kinase A signaling pathway inhibits endothelin type A receptor-operated Ca(2)(+) entry mediated via transient receptor potential canonical 6 channels. External Horinouchi, T., Higa, T., Aoyagi, H., Nishiya, T., Terada, K., Miwa, S. J Pharmacol Exp Ther 2012
21996795 Expression and association of TRPC1 with TRPC3 during skeletal myogenesis. External Cheung, K. K., Yeung, S. S., Au, S. W., Lam, L. S., Dai, Z. Q., Li, Y. H., Yeung, E. W. Muscle Nerve 2011
21968068 TRPC1 proteins confer PKC and phosphoinositol activation on native heteromeric TRPC1/C5 channels in vascular smooth muscle: comparative study of wild-type and TRPC1-/- mice. External Shi, J., Ju, M., Abramowitz, J., Large, W. A., Birnbaumer, L., Albert, A. P. FASEB J 2012
21952826 Tissue transglutaminase inhibits the TRPV5-dependent calcium transport in an N-glycosylation-dependent manner. External Boros, S., Xi, Q., Dimke, H., van der Kemp, A. W., Tudpor, K., Verkaart, S., Lee, K. P., Bindels, R. J., Hoenderop, J. G. Cell Mol Life Sci 2012
21906983 Systematic and quantitative assessment of the ubiquitin-modified proteome. External Kim, W., Bennett, E. J., Huttlin, E. L., Guo, A., Li, J., Possemato, A., Sowa, M. E., Rad, R., Rush, J., Comb, M. J., Harper, J. W., Gygi, S. P. Mol Cell 2011
21890473 A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. External Wagner, S. A., Beli, P., Weinert, B. T., Nielsen, M. L., Cox, J., Mann, M., Choudhary, C. Mol Cell Proteomics 2011
21871867 Electrophysiological properties of heteromeric TRPV4-C1 channels. External Ma, X., Nilius, B., Wong, J. W., Huang, Y., Yao, X. Biochim Biophys Acta 2011
21844219 Coexpression and activation of TRPV1 suppress the activity of the KCNQ2/3 channel. External Zhang, X. F., Han, P., Neelands, T. R., McGaraughty, S., Honore, P., Surowy, C. S., Zhang, D. J Gen Physiol 2011
21837266 Mutation of a putative S-nitrosylation site of TRPV4 protein facilitates the channel activates. External Lee, E. J., Shin, S. H., Hyun, S., Chun, J., Kang, S. S. Animal Cells Syst (Seoul) 2011
21832182 TRPM1 forms complexes with nyctalopin in vivo and accumulates in postsynaptic compartment of ON-bipolar neurons in mGluR6-dependent manner. External Cao, Y., Posokhova, E., Martemyanov, K. A. J Neurosci 2011
21799177 Cilostazol suppresses angiotensin II-induced vasoconstriction via protein kinase A-mediated phosphorylation of the transient receptor potential canonical 6 channel. External Nishioka, K., Nishida, M., Ariyoshi, M., Jian, Z., Saiki, S., Hirano, M., Nakaya, M., Sato, Y., Kita, S., Iwamoto, T., Hirano, K., Inoue, R., Kurose, H. Arterioscler Thromb Vasc Biol 2011
21757714 The transient receptor potential (TRP) channel TRPC3 TRP domain and AMP-activated protein kinase binding site are required for TRPC3 activation by erythropoietin. External Hirschler-Laszkiewicz, I., Tong, Q., Waybill, K., Conrad, K., Keefer, K., Zhang, W., Chen, S. J., Cheung, J. Y., Miller, B. A. J Biol Chem 2011
21734298 A role for nyctalopin, a small leucine-rich repeat protein, in localizing the TRP melastatin 1 channel to retinal depolarizing bipolar cell dendrites. External Pearring, J. N., Bojang, P. Jr, Shen, Y., Koike, C., Furukawa, T., Nawy, S., Gregg, R. G. J Neurosci 2011
21672930 A key role of TRPC channels in the regulation of electromechanical activity of the developing heart. External Sabourin, J., Robin, E., Raddatz, E. Cardiovasc Res 2011
21670282 Serine-threonine kinase with-no-lysine 4 (WNK4) controls blood pressure via transient receptor potential canonical 3 (TRPC3) in the vasculature. External Park, H. W., Kim, J. Y., Choi, S. K., Lee, Y. H., Zeng, W., Kim, K. H., Muallem, S., Lee, M. G. Proc Natl Acad Sci U S A 2011
21576356 Molecular mechanisms of calmodulin action on TRPV5 and modulation by parathyroid hormone. External de Groot, T., Kovalevskaya, N. V., Verkaart, S., Schilderink, N., Felici, M., van der Hagen, E. A., Bindels, R. J., Vuister, G. W., Hoenderop, J. G. Mol Cell Biol 2011
21540176 Transient receptor potential mucolipin 1 (TRPML1) and two-pore channels are functionally independent organellar ion channels. External Yamaguchi, S., Jha, A., Li, Q., Soyombo, A. A., Dickinson, G. D., Churamani, D., Brailoiu, E., Patel, S., Muallem, S. J Biol Chem 2011
21493704 Molecular mechanisms of activation of endothelial nitric oxide synthase mediated by transient receptor potential vanilloid type 1. External Ching, L. C., Kou, Y. R., Shyue, S. K., Su, K. H., Wei, J., Cheng, L. C., Yu, Y. B., Pan, C. C., Lee, T. S. Cardiovasc Res 2011
21402151 Functional regulation of transient receptor potential canonical 7 by cGMP-dependent protein kinase Ialpha. External Yuasa, K., Matsuda, T., Tsuji, A. Cell Signal 2011
21307093 Pkd1l1 establishes left-right asymmetry and physically interacts with Pkd2. External Field, S., Riley, K. L., Grimes, D. T., Hilton, H., Simon, M., Powles-Glover, N., Siggers, P., Bogani, D., Greenfield, A., Norris, D. P. Development 2011
21278253 Transient receptor potential melastatin 1 (TRPM1) is an ion-conducting plasma membrane channel inhibited by zinc ions. External Lambert, S., Drews, A., Rizun, O., Wagner, T. F., Lis, A., Mannebach, S., Plant, S., Portz, M., Meissner, M., Philipp, S. E., Oberwinkler, J. J Biol Chem 2011
21262839 An aquaporin-4/transient receptor potential vanilloid 4 (AQP4/TRPV4) complex is essential for cell-volume control in astrocytes. External Benfenati, V., Caprini, M., Dovizio, M., Mylonakou, M. N., Ferroni, S., Ottersen, O. P., Amiry-Moghaddam, M. Proc Natl Acad Sci U S A 2011
21224396 LAPTMs regulate lysosomal function and interact with mucolipin 1: new clues for understanding mucolipidosis type IV. External Vergarajauregui, S., Martina, J. A., Puertollano, R. J Cell Sci 2011
21139048 Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. External Danielsen, J. M., Sylvestersen, K. B., Bekker-Jensen, S., Szklarczyk, D., Poulsen, J. W., Horn, H., Jensen, L. J., Mailand, N., Nielsen, M. L. Mol Cell Proteomics 2011
20926660 Ca2+-dependent desensitization of TRPV2 channels is mediated by hydrolysis of phosphatidylinositol 4,5-bisphosphate. External Mercado, J., Gordon-Shaag, A., Zagotta, W. N., Gordon, S. E. J Neurosci 2010
20811636 The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1. External Giannone, R. J., McDonald, H. W., Hurst, G. B., Shen, R. F., Wang, Y., Liu, Y. PLoS One 2010
20736310 Heteromultimeric TRPML channel assemblies play a crucial role in the regulation of cell viability models and starvation-induced autophagy. External Zeevi, D. A., Lev, S., Frumkin, A., Minke, B., Bach, G. J Cell Sci 2010
20729296 The retinitis pigmentosa protein RP2 interacts with polycystin 2 and regulates cilia-mediated vertebrate development. External Hurd, T., Zhou, W., Jenkins, P., Liu, C. J., Swaroop, A., Khanna, H., Martens, J., Hildebrandt, F., Margolis, B. Hum Mol Genet 2010
20705915 Depletion of intracellular Ca2+ stores stimulates the translocation of vanilloid transient receptor potential 4-c1 heteromeric channels to the plasma membrane. External Ma, X., Cao, J., Luo, J., Nilius, B., Huang, Y., Ambudkar, I. S., Yao, X. Arterioscler Thromb Vasc Biol 2010
20686800 Characterization of calmodulin binding domains in TRPV2 and TRPV5 C-tails. External Holakovska, B., Grycova, L., Bily, J., Teisinger, J. Amino Acids 2011
20682256 Atomic force microscopy reveals the alternating subunit arrangement of the TRPP2-TRPV4 heterotetramer. External Stewart, A. P., Smith, G. D., Sandford, R. N., Edwardson, J. M. Biophys J 2010
20660561 TRPC6 channels stimulated by angiotensin II are inhibited by TRPC1/C5 channel activity through a Ca2+- and PKC-dependent mechanism in native vascular myocytes. External Shi, J., Ju, M., Saleh, S. N., Albert, A. P., Large, W. A. J Physiol 2010
20650893 Arresting a transient receptor potential (TRP) channel: beta-arrestin 1 mediates ubiquitination and functional down-regulation of TRPV4. External Shukla, A. K., Kim, J., Ahn, S., Xiao, K., Shenoy, S. K., Liedtke, W., Lefkowitz, R. J. J Biol Chem 2010
20538909 Interaction between PKD1L3 and PKD2L1 through their transmembrane domains is required for localization of PKD2L1 at taste pores in taste cells of circumvallate and foliate papillae. External Ishimaru, Y., Katano, Y., Yamamoto, K., Akiba, M., Misaka, T., Roberts, R. W., Asakura, T., Matsunami, H., Abe, K. FASEB J 2010
20492691 The TRPC2 channel forms protein-protein interactions with Homer and RTP in the rat vomeronasal organ. External Mast, T. G., Brann, J. H., Fadool, D. A. BMC Neurosci 2010
20488539 Effect of cell swelling on ER/PM junctional interactions and channel assembly involved in SOCE. External Liu, X., Ong, H. L., Pani, B., Johnson, K., Swaim, W. B., Singh, B., Ambudkar, I. Cell Calcium 2010
20413591 The TRPV4 channel contributes to intercellular junction formation in keratinocytes. External Sokabe, T., Fukumi-Tominaga, T., Yonemura, S., Mizuno, A., Tominaga, M. J Biol Chem 2010
20403327 TRP channel regulates EGFR signaling in hair morphogenesis and skin barrier formation. External Cheng, X., Jin, J., Hu, L., Shen, D., Dong, X. P., Samie, M. A., Knoff, J., Eisinger, B., Liu, M. L., Huang, S. M., Caterina, M. J., Dempsey, P., Michael, L. E., Dlugosz, A. A., Andrews, N. C., Clapham, D. E., Xu, H. Cell 2010
20378853 Isoform-selective physical coupling of TRPC3 channels to IP3 receptors in smooth muscle cells regulates arterial contractility. External Adebiyi, A., Zhao, G., Narayanan, D., Thomas-Gatewood, C. M., Bannister, J. P., Jaggar, J. H. Circ Res 2010
20375013 Polycystin-2 activation by inositol 1,4,5-trisphosphate-induced Ca2+ release requires its direct association with the inositol 1,4,5-trisphosphate receptor in a signaling microdomain. External Sammels, E., Devogelaere, B., Mekahli, D., Bultynck, G., Missiaen, L., Parys, J. B., Cai, Y., Somlo, S., De Smedt, H. J Biol Chem 2010
20351294 TRPC channels are necessary mediators of pathologic cardiac hypertrophy. External Wu, X., Eder, P., Chang, B., Molkentin, J. D. Proc Natl Acad Sci U S A 2010
20346379 Involvement of Rab9 and Rab11 in the intracellular trafficking of TRPC6. External Cayouette, S., Bousquet, S. M., Francoeur, N., Dupre, E., Monet, M., Gagnon, H., Guedri, Y. B., Lavoie, C., Boulay, G. Biochim Biophys Acta 2010
20231274 Contribution of TRPV1-TRPA1 interaction to the single channel properties of the TRPA1 channel. External Staruschenko, A., Jeske, N. A., Akopian, A. N. J Biol Chem 2010
20194530 Expression and association of TRPC subtypes with Orai1 and STIM1 in human parathyroid. External Lu, M., Branstrom, R., Berglund, E., Hoog, A., Bjorklund, P., Westin, G., Larsson, C., Farnebo, L. O., Forsberg, L. J Mol Endocrinol 2010
20179142 GABAA receptor associated protein (GABARAP) modulates TRPV1 expression and channel function and desensitization. External Lainez, S., Valente, P., Ontoria-Oviedo, I., Estevez-Herrera, J., Camprubi-Robles, M., Ferrer-Montiel, A., Planells-Cases, R. FASEB J 2010
20179100 Ca2+ influx and protein scaffolding via TRPC3 sustain PKCbeta and ERK activation in B cells. External Numaga, T., Nishida, M., Kiyonaka, S., Kato, K., Katano, M., Mori, E., Kurosaki, T., Inoue, R., Hikida, M., Putney, J. W. Jr, Mori, Y. J Cell Sci 2010
20164195 The phospholipid-binding protein SESTD1 is a novel regulator of the transient receptor potential channels TRPC4 and TRPC5. External Miehe, S., Bieberstein, A., Arnould, I., Ihdene, O., Rutten, H., Strubing, C. J Biol Chem 2010
20107112 Role of cAMP/PKA signaling cascade in vasopressin-induced trafficking of TRPC3 channels in principal cells of the collecting duct. External Goel, M., Zuo, C. D., Schilling, W. P. Am J Physiol Renal Physiol 2010
20095964 S165F mutation of junctophilin 2 affects Ca2+ signalling in skeletal muscle. External Woo, J. S., Hwang, J. H., Ko, J. K., Weisleder, N., Kim do, H., Ma, J., Lee, E. H. Biochem J 2010
20093626 Functional role of vanilloid transient receptor potential 4-canonical transient receptor potential 1 complex in flow-induced Ca2+ influx. External Ma, X., Qiu, S., Luo, J., Ma, Y., Ngai, C. Y., Shen, B., Wong, C. O., Huang, Y., Yao, X. Arterioscler Thromb Vasc Biol 2010
20022948 TRPC3 regulates agonist-stimulated Ca2+ mobilization by mediating the interaction between type I inositol 1,4,5-trisphosphate receptor, RACK1, and Orai1. External Woodard, G. E., Lopez, J. J., Jardin, I., Salido, G. M., Rosado, J. A. J Biol Chem 2010
19996314 Cell-cell contact formation governs Ca2+ signaling by TRPC4 in the vascular endothelium: evidence for a regulatory TRPC4-beta-catenin interaction. External Graziani, A., Poteser, M., Heupel, W. M., Schleifer, H., Krenn, M., Drenckhahn, D., Romanin, C., Baumgartner, W., Groschner, K. J Biol Chem 2010
19945390 Peptidyl-prolyl isomerase FKBP52 controls chemotropic guidance of neuronal growth cones via regulation of TRPC1 channel opening. External Shim, S., Yuan, J. P., Kim, J. Y., Zeng, W., Huang, G., Milshteyn, A., Kern, D., Muallem, S., Ming, G. L., Worley, P. F. Neuron 2009
19932145 The interactions of the C-terminal region of the TRPC6 channel with calmodulin. External Friedlova, E., Grycova, L., Holakovska, B., Silhan, J., Janouskova, H., Sulc, M., Obsilova, V., Obsil, T., Teisinger, J. Neurochem Int 2010
19897728 Activation of TRPC1 by STIM1 in ER-PM microdomains involves release of the channel from its scaffold caveolin-1. External Pani, B., Ong, H. L., Brazer, S. C., Liu, X., Rauser, K., Singh, B. B., Ambudkar, I. S. Proc Natl Acad Sci U S A 2009
19885840 Functional multimerization of mucolipin channel proteins. External Curcio-Morelli, C., Zhang, P., Venugopal, B., Charles, F. A., Browning, M. F., Cantiello, H. F., Slaugenhaupt, S. A. J Cell Physiol 2010
19879844 Polycystin-1 and -2 dosage regulates pressure sensing. External Sharif-Naeini, R., Folgering, J. H., Bichet, D., Duprat, F., Lauritzen, I., Arhatte, M., Jodar, M., Dedman, A., Chatelain, F. C., Schulte, U., Retailleau, K., Loufrani, L., Patel, A., Sachs, F., Delmas, P., Peters, D. J., Honore, E. Cell 2009
19864432 Differential regulation of TRPV1, TRPV3, and TRPV4 sensitivity through a conserved binding site on the ankyrin repeat domain. External Phelps, C. B., Wang, R. R., Choo, S. S., Gaudet, R. J Biol Chem 2010
19864416 Identification of the penta-EF-hand protein ALG-2 as a Ca2+-dependent interactor of mucolipin-1. External Vergarajauregui, S., Martina, J. A., Puertollano, R. J Biol Chem 2009
19850920 The transient receptor potential channels TRPP2 and TRPC1 form a heterotetramer with a 2:2 stoichiometry and an alternating subunit arrangement. External Kobori, T., Smith, G. D., Sandford, R., Edwardson, J. M. J Biol Chem 2009
19812035 A pathogenic C terminus-truncated polycystin-2 mutant enhances receptor-activated Ca2+ entry via association with TRPC3 and TRPC7. External Miyagi, K., Kiyonaka, S., Yamada, K., Miki, T., Mori, E., Kato, K., Numata, T., Sawaguchi, Y., Numaga, T., Kimura, T., Kanai, Y., Kawano, M., Wakamori, M., Nomura, H., Koni, I., Yamagishi, M., Mori, Y. J Biol Chem 2009
19812031 Regulation of TRPC1 and TRPC4 cation channels requires an alpha1-syntrophin-dependent complex in skeletal mouse myotubes. External Sabourin, J., Lamiche, C., Vandebrouck, A., Magaud, C., Rivet, J., Cognard, C., Bourmeyster, N., Constantin, B. J Biol Chem 2009
19801576 PRKCSH/80K-H, the protein mutated in polycystic liver disease, protects polycystin-2/TRPP2 against HERP-mediated degradation. External Gao, H., Wang, Y., Wegierski, T., Skouloudaki, K., Putz, M., Fu, X., Engel, C., Boehlke, C., Peng, H., Kuehn, E. W., Kim, E., Kramer-Zucker, A., Walz, G. Hum Mol Genet 2010
19726544 Analysis of the cytoplasmic interaction between polycystin-1 and polycystin-2. External Casuscelli, J., Schmidt, S., DeGray, B., Petri, E. T., Celic, A., Folta-Stogniew, E., Ehrlich, B. E., Boggon, T. J. Am J Physiol Renal Physiol 2009
19689790 Abnormal expression, localization and interaction of canonical transient receptor potential ion channels in human breast cancer cell lines and tissues: a potential target for breast cancer diagnosis and therapy. External Aydar, E., Yeo, S., Djamgoz, M., Palmer, C. Cancer Cell Int 2009
19557826 A potentially dynamic lysosomal role for the endogenous TRPML proteins. External Zeevi, D. A., Frumkin, A., Offen-Glasner, V., Kogot-Levin, A., Bach, G. J Pathol 2009
19556541 Structural and molecular basis of the assembly of the TRPP2/PKD1 complex. External Yu, Y., Ulbrich, M. H., Li, M. H., Buraei, Z., Chen, X. Z., Ong, A. C., Tong, L., Isacoff, E. Y., Yang, J. Proc Natl Acad Sci U S A 2009
19522758 The Ca(2+) channel TRPML3 regulates membrane trafficking and autophagy. External Kim, H. J., Soyombo, A. A., Tjon-Kon-Sang, S., So, I., Muallem, S. Traffic 2009
19502552 Inhibition of TRPC1/TRPC3 by PKG contributes to NO-mediated vasorelaxation. External Chen, J., Crossland, R. F., Noorani, M. M., Marrelli, S. P. Am J Physiol Heart Circ Physiol 2009
19351713 Regulation of transient receptor potential canonical channel 1 (TRPC1) by sphingosine 1-phosphate in C2C12 myoblasts and its relevance for a role of mechanotransduction in skeletal muscle differentiation. External Formigli, L., Sassoli, C., Squecco, R., Bini, F., Martinesi, M., Chellini, F., Luciani, G., Sbrana, F., Zecchi-Orlandini, S., Francini, F., Meacci, E. J Cell Sci 2009
19332490 TRPC1 and STIM1 mediate capacitative Ca2+ entry in mouse pulmonary arterial smooth muscle cells. External Ng, L. C., McCormack, M. D., Airey, J. A., Singer, C. A., Keller, P. S., Shen, X. M., Hume, J. R. J Physiol 2009
19329436 Regulation of the epithelial Mg2+ channel TRPM6 by estrogen and the associated repressor protein of estrogen receptor activity (REA). External Cao, G., van der Wijst, J., van der Kemp, A., van Zeeland, F., Bindels, R. J., Hoenderop, J. G. J Biol Chem 2009
19307462 Interaction between TRPC1/TRPC4 assembly and STIM1 contributes to store-operated Ca2+ entry in mesangial cells. External Sours-Brothers, S., Ding, M., Graham, S., Ma, R. Exp Biol Med (Maywood) 2009
19295174 Endogenous expression of TRPV5 and TRPV6 calcium channels in human leukemia K562 cells. External Semenova, S. B., Vassilieva, I. O., Fomina, A. F., Runov, A. L., Negulyaev, Y. A. Am J Physiol Cell Physiol 2009
19289841 Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound. External Kiyonaka, S., Kato, K., Nishida, M., Mio, K., Numaga, T., Sawaguchi, Y., Yoshida, T., Wakamori, M., Mori, E., Numata, T., Ishii, M., Takemoto, H., Ojida, A., Watanabe, K., Uemura, A., Kurose, H., Morii, T., Kobayashi, T., Sato, Y., Sato, C., Hamachi, I., Mori, Y. Proc Natl Acad Sci U S A 2009
19277847 Glutamate at position 227 of junctophilin-2 is involved in binding to TRPC3. External Woo, J. S., Hwang, J. H., Ko, J. K., Kim do, H., Ma, J., Lee, E. H. Mol Cell Biochem 2009
19260825 Dynamic interaction of hTRPC6 with the Orai1-STIM1 complex or hTRPC3 mediates its role in capacitative or non-capacitative Ca(2+) entry pathways. External Jardin, I., Gomez, L. J., Salido, G. M., Rosado, J. A. Biochem J 2009
19228695 Native Store-operated Ca2+ Influx Requires the Channel Function of Orai1 and TRPC1. External Kim, M. S., Zeng, W., Yuan, J. P., Shin, D. M., Worley, P. F., Muallem, S. J Biol Chem 2009
19228120 Identification of dimer interactions required for the catalytic activity of the TRPM7 alpha-kinase domain. External Crawley, S. W., Cote, G. P. Biochem J 2009
19223122 Cross-inhibition between native and recombinant TRPV1 and P2X(3) receptors. External Stanchev, D., Blosa, M., Milius, D., Gerevich, Z., Rubini, P., Schmalzing, G., Eschrich, K., Schaefer, M., Wirkner, K., Illes, P. Pain 2009
19193631 The multimeric structure of polycystin-2 (TRPP2): structural-functional correlates of homo- and hetero-multimers with TRPC1. External Zhang, P., Luo, Y., Chasan, B., Gonzalez-Perrett, S., Montalbetti, N., Timpanaro, G. A., Cantero Mdel, R., Ramos, A. J., Goldmann, W. H., Zhou, J., Cantiello, H. F. Hum Mol Genet 2009
19168436 TRPC1 associates with BK(Ca) channel to form a signal complex in vascular smooth muscle cells. External Kwan, H. Y., Shen, B., Ma, X., Kwok, Y. C., Huang, Y., Man, Y. B., Yu, S., Yao, X. Circ Res 2009
19155296 Transient receptor potential type vanilloid 1 suppresses skin carcinogenesis. External Bode, A. M., Cho, Y. Y., Zheng, D., Zhu, F., Ericson, M. E., Ma, W. Y., Yao, K., Dong, Z. Cancer Res 2009
19117012 Chaperone-mediated autophagy is defective in mucolipidosis type IV. External Venugopal, B., Mesires, N. T., Kennedy, J. C., Curcio-Morelli, C., Laplante, J. M., Dice, J. F., Slaugenhaupt, S. A. J Cell Physiol 2009
19074769 TRPC3 activation by erythropoietin is modulated by TRPC6. External Hirschler-Laszkiewicz, I., Tong, Q., Conrad, K., Zhang, W., Flint, W. W., Barber, A. J., Barber, D. L., Cheung, J. Y., Miller, B. A. J Biol Chem 2009
19052258 Caveolin-1 scaffold domain interacts with TRPC1 and IP3R3 to regulate Ca2+ store release-induced Ca2+ entry in endothelial cells. External Sundivakkam, P. C., Kwiatek, A. M., Sharma, T. T., Minshall, R. D., Malik, A. B., Tiruppathi, C. Am J Physiol Cell Physiol 2009
19052171 Canonical transient receptor potential channel (TRPC)3 and TRPC6 associate with large-conductance Ca2+-activated K+ (BKCa) channels: role in BKCa trafficking to the surface of cultured podocytes. External Kim, E. Y., Alvarez-Baron, C. P., Dryer, S. E. Mol Pharmacol 2009
19033444 Tyrosine phosphorylation modulates the activity of TRPV4 in response to defined stimuli. External Wegierski, T., Lewandrowski, U., Muller, B., Sickmann, A., Walz, G. J Biol Chem 2009
19027987 Functional interaction of the cation channel transient receptor potential vanilloid 4 (TRPV4) and actin in volume regulation. External Becker, D., Bereiter-Hahn, J., Jendrach, M. Eur J Cell Biol 2009
18836075 Syntaxin 5 regulates the endoplasmic reticulum channel-release properties of polycystin-2. External Geng, L., Boehmerle, W., Maeda, Y., Okuhara, D. Y., Tian, X., Yu, Z., Choe, C. U., Anyatonwu, G. I., Ehrlich, B. E., Somlo, S. Proc Natl Acad Sci U S A 2008
18826956 IP3 receptor binds to and sensitizes TRPV4 channel to osmotic stimuli via a calmodulin-binding site. External Garcia-Elias, A., Lorenzo, I. M., Vicente, R., Valverde, M. A. J Biol Chem 2008
18802106 Secretogranin III directs secretory vesicle biogenesis in mast cells in a manner dependent upon interaction with chromogranin A. External Prasad, P., Yanagihara, A. A., Small-Howard, A. L., Turner, H., Stokes, A. J. J Immunol 2008
18802022 Interactions, functions, and independence of plasma membrane STIM1 and TRPC1 in vascular smooth muscle cells. External Li, J., Sukumar, P., Milligan, C. J., Kumar, B., Ma, Z. Y., Munsch, C. M., Jiang, L. H., Porter, K. E., Beech, D. J. Circ Res 2008
18782757 Polycystin-2 expression is regulated by a PC2-binding domain in the intracellular portion of fibrocystin. External Kim, I., Li, C., Liang, D., Chen, X. Z., Coffy, R. J., Ma, J., Zhao, P., Wu, G. J Biol Chem 2008
18755685 TRPC3 controls agonist-stimulated intracellular Ca2+ release by mediating the interaction between inositol 1,4,5-trisphosphate receptor and RACK1. External Bandyopadhyay, B. C., Ong, H. L., Lockwich, T. P., Liu, X., Paria, B. C., Singh, B. B., Ambudkar, I. S. J Biol Chem 2008
18701070 Proinflammatory mediators modulate the heat-activated ion channel TRPV1 via the scaffolding protein AKAP79/150. External Zhang, X., Li, L., McNaughton, P. A. Neuron 2008
18695040 TRPP2 and TRPV4 form a polymodal sensory channel complex. External Kottgen, M., Buchholz, B., Garcia-Gonzalez, M. A., Kotsis, F., Fu, X., Doerken, M., Boehlke, C., Steffl, D., Tauber, R., Wegierski, T., Nitschke, R., Suzuki, M., Kramer-Zucker, A., Germino, G. G., Watnick, T., Prenen, J., Nilius, B., Kuehn, E. W., Walz, G. J Cell Biol 2008
18664456 Polycystin-2 down-regulates cell proliferation via promoting PERK-dependent phosphorylation of eIF2alpha. External Liang, G., Yang, J., Wang, Z., Li, Q., Tang, Y., Chen, X. Z. Hum Mol Genet 2008
18644792 Orai1 mediates the interaction between STIM1 and hTRPC1 and regulates the mode of activation of hTRPC1-forming Ca2+ channels. External Jardin, I., Lopez, J. J., Salido, G. M., Rosado, J. A. J Biol Chem 2008
18617565 Nitric oxide-cGMP-protein kinase G pathway negatively regulates vascular transient receptor potential channel TRPC6. External Takahashi, S., Lin, H., Geshi, N., Mori, Y., Kawarabayashi, Y., Takami, N., Mori, M. X., Honda, A., Inoue, R. J Physiol 2008
18606998 Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1. External Cha, S. K., Ortega, B., Kurosu, H., Rosenblatt, K. P., Kuro-O, M., Huang, C. L. Proc Natl Acad Sci U S A 2008
18544631 TRPC1 binds to caveolin-3 and is regulated by Src kinase - role in Duchenne muscular dystrophy. External Gervasio, O. L., Whitehead, N. P., Yeung, E. W., Phillips, W. D., Allen, D. G. J Cell Sci 2008
18535624 Off-response property of an acid-activated cation channel complex PKD1L3-PKD2L1. External Inada, H., Kawabata, F., Ishimaru, Y., Fushiki, T., Matsunami, H., Tominaga, M. EMBO Rep 2008
18502908 ATP/UTP activate cation-permeable channels with TRPC3/7 properties in rat cardiomyocytes. External Alvarez, J., Coulombe, A., Cazorla, O., Ugur, M., Rauzier, J. M., Magyar, J., Mathieu, E. L., Boulay, G., Souto, R., Bideaux, P., Salazar, G., Rassendren, F., Lacampagne, A., Fauconnier, J., Vassort, G. Am J Physiol Heart Circ Physiol 2008
18495742 The beta-glucuronidase klotho exclusively activates the epithelial Ca2+ channels TRPV5 and TRPV6. External Lu, P., Boros, S., Chang, Q., Bindels, R. J., Hoenderop, J. G. Nephrol Dial Transplant 2008
18463244 Protein kinase A anchoring via AKAP150 is essential for TRPV1 modulation by forskolin and prostaglandin E2 in mouse sensory neurons. External Schnizler, K., Shutov, L. P., Van Kanegan, M. J., Merrill, M. A., Nichols, B., McKnight, G. S., Strack, S., Hell, J. W., Usachev, Y. M. J Neurosci 2008
18455988 Pirt, a phosphoinositide-binding protein, functions as a regulatory subunit of TRPV1. External Kim, A. Y., Tang, Z., Liu, Q., Patel, K. N., Maag, D., Geng, Y., Dong, X. Cell 2008
18445599 The human TRPV6 channel protein is associated with cyclophilin B in human placenta. External Stumpf, T., Zhang, Q., Hirnet, D., Lewandrowski, U., Sickmann, A., Wissenbach, U., Dorr, J., Lohr, C., Deitmer, J. W., Fecher-Trost, C. J Biol Chem 2008
18430726 Lipid rafts determine clustering of STIM1 in endoplasmic reticulum-plasma membrane junctions and regulation of store-operated Ca2+ entry (SOCE). External Pani, B., Ong, H. L., Liu, X., Rauser, K., Ambudkar, I. S., Singh, B. B. J Biol Chem 2008
18392847 Identification of Nipsnap1 as a novel auxiliary protein inhibiting TRPV6 activity. External Schoeber, J. P., Topala, C. N., Lee, K. P., Lambers, T. T., Ricard, G., van der Kemp, A. W., Huynen, M. A., Hoenderop, J. G., Bindels, R. J. Pflugers Arch 2008
18381233 A-kinase anchoring protein mediates TRPV1 thermal hyperalgesia through PKA phosphorylation of TRPV1. External Jeske, N. A., Diogenes, A., Ruparel, N. B., Fehrenbacher, J. C., Henry, M., Akopian, A. N., Hargreaves, K. M. Pain 2008
18378772 IP3 sensitizes TRPV4 channel to the mechano- and osmotransducing messenger 5'-6'-epoxyeicosatrienoic acid. External Fernandes, J., Lorenzo, I. M., Andrade, Y. N., Garcia-Elias, A., Serra, S. A., Fernandez-Fernandez, J. M., Valverde, M. A. J Cell Biol 2008
18356201 Diverse properties of store-operated TRPC channels activated by protein kinase C in vascular myocytes. External Saleh, S. N., Albert, A. P., Peppiatt-Wildman, C. M., Large, W. A. J Physiol 2008
18326500 Functional requirement for Orai1 in store-operated TRPC1-STIM1 channels. External Cheng, K. T., Liu, X., Ong, H. L., Ambudkar, I. S. J Biol Chem 2008
18323855 Formation of a new receptor-operated channel by heteromeric assembly of TRPP2 and TRPC1 subunits. External Bai, C. X., Giamarchi, A., Rodat-Despoix, L., Padilla, F., Downs, T., Tsiokas, L., Delmas, P. EMBO Rep 2008
18287061 Functional interactions among Orai1, TRPCs, and STIM1 suggest a STIM-regulated heteromeric Orai/TRPC model for SOCE/Icrac channels. External Liao, Y., Erxleben, C., Abramowitz, J., Flockerzi, V., Zhu, M. X., Armstrong, D. L., Birnbaumer, L. Proc Natl Acad Sci U S A 2008
18276585 TRPC3 is the erythropoietin-regulated calcium channel in human erythroid cells. External Tong, Q., Hirschler-Laszkiewicz, I., Zhang, W., Conrad, K., Neagley, D. W., Barber, D. L., Cheung, J. Y., Miller, B. A. J Biol Chem 2008
18273441 Kidney injury molecule 1 (Kim1) is a novel ciliary molecule and interactor of polycystin 2. External Kuehn, E. W., Hirt, M. N., John, A. K., Muehlenhardt, P., Boehlke, C., Putz, M., Kramer-Zucker, A. G., Bashkurov, M., van de Weyer, P. S., Kotsis, F., Walz, G. Biochem Biophys Res Commun 2007
18268005 Mice lacking Homer 1 exhibit a skeletal myopathy characterized by abnormal transient receptor potential channel activity. External Stiber, J. A., Zhang, Z. S., Burch, J., Eu, J. P., Zhang, S., Truskey, G. A., Seth, M., Yamaguchi, N., Meissner, G., Shah, R., Worley, P. F., Williams, R. S., Rosenberg, P. B. Mol Cell Biol 2008
18262493 TRPM4b channel suppresses store-operated Ca2+ entry by a novel protein-protein interaction with the TRPC3 channel. External Park, J. Y., Hwang, E. M., Yarishkin, O., Seo, J. H., Kim, E., Yoo, J., Yi, G. S., Kim, D. G., Park, N., Ha, C. M., La, J. H., Kang, D., Han, J., Oh, U., Hong, S. G. Biochem Biophys Res Commun 2008
18261457 Interaction with dopamine D2 receptor enhances expression of transient receptor potential channel 1 at the cell surface. External Hannan, M. A., Kabbani, N., Paspalas, C. D., Levenson, R. Biochim Biophys Acta 2008
18258429 RACK1 inhibits TRPM6 activity via phosphorylation of the fused alpha-kinase domain. External Cao, G., Thebault, S., van der Wijst, J., van der Kemp, A., Lasonder, E., Bindels, R. J., Hoenderop, J. G. Curr Biol 2008
18256307 Mediation of angiotensin II-induced Ca2+ signaling by polycystin 2 in glomerular mesangial cells. External Du, J., Ding, M., Sours-Brothers, S., Graham, S., Ma, R. Am J Physiol Renal Physiol 2008
18249094 Functional relevance of the de novo coupling between hTRPC1 and type II IP3 receptor in store-operated Ca2+ entry in human platelets. External Jardin, I., Lopez, J. J., Salido, G. M., Rosado, J. A. Cell Signal 2008
18235101 Nek8 regulates the expression and localization of polycystin-1 and polycystin-2. External Sohara, E., Luo, Y., Zhang, J., Manning, D. K., Beier, D. R., Zhou, J. J Am Soc Nephrol 2008
18235088 Fibrocystin/polyductin modulates renal tubular formation by regulating polycystin-2 expression and function. External Kim, I., Fu, Y., Hui, K., Moeckel, G., Mai, W., Li, C., Liang, D., Zhao, P., Ma, J., Chen, X. Z., George, A. L. Jr, Coffey, R. J., Feng, Z. P., Wu, G. J Am Soc Nephrol 2008
18234883 Interaction of transient receptor potential vanilloid 4, integrin, and SRC tyrosine kinase in mechanical hyperalgesia. External Alessandri-Haber, N., Dina, O. A., Joseph, E. K., Reichling, D. B., Levine, J. D. J Neurosci 2008
18215135 TRPC3-interacting triadic proteins in skeletal muscle. External Woo, J. S., Kim do, H., Allen, P. D., Lee, E. H. Biochem J 2008
18205297 Analysis of TRPC3-interacting proteins by tandem mass spectrometry. External Lockwich, T., Pant, J., Makusky, A., Jankowska-Stephens, E., Kowalak, J. A., Markey, S. P., Ambudkar, I. S. J Proteome Res 2008
18191041 Intracellular Ca2+ store depletion induces the formation of macromolecular complexes involving hTRPC1, hTRPC6, the type II IP3 receptor and SERCA3 in human platelets. External Redondo, P. C., Jardin, I., Lopez, J. J., Salido, G. M., Rosado, J. A. Biochim Biophys Acta 2008
18187190 The annexin 2-S100A10 complex and its association with TRPV6 is regulated by cAMP/PKA/CnA in airway and gut epithelia. External Borthwick, L. A., Neal, A., Hobson, L., Gerke, V., Robson, L., Muimo, R. Cell Calcium 2008
18178578 Polycystin-2 is regulated by endoplasmic reticulum-associated degradation. External Liang, G., Li, Q., Tang, Y., Kokame, K., Kikuchi, T., Wu, G., Chen, X. Z. Hum Mol Genet 2008
18174177 Stimulus-specific modulation of the cation channel TRPV4 by PACSIN 3. External D'hoedt, D., Owsianik, G., Prenen, J., Cuajungco, M. P., Grimm, C., Heller, S., Voets, T., Nilius, B. J Biol Chem 2008
18068335 SERCA2b and 3 play a regulatory role in store-operated calcium entry in human platelets. External Redondo, P. C., Salido, G. M., Pariente, J. A., Sage, S. O., Rosado, J. A. Cell Signal 2008
18063480 Interaction between protein kinase D1 and transient receptor potential V1 in primary sensory neurons is involved in heat hypersensitivity. External Zhu, H., Yang, Y., Zhang, H., Han, Y., Li, Y., Zhang, Y., Yin, D., He, Q., Zhao, Z., Blumberg, P. M., Han, J., Wang, Y. Pain 2008
18048348 The spectrin cytoskeleton influences the surface expression and activation of human transient receptor potential channel 4 channels. External Odell, A. F., Van Helden, D. F., Scott, J. L. J Biol Chem 2008
17988215 Mucolipin 1 channel activity is regulated by protein kinase A-mediated phosphorylation. External Vergarajauregui, S., Oberdick, R., Kiselyov, K., Puertollano, R. Biochem J 2008
17944866 Direct binding of alpha-actinin enhances TRPP3 channel activity. External Li, Q., Dai, X. Q., Shen, P. Y., Wu, Y., Long, W., Chen, C. X., Hussain, Z., Wang, S., Chen, X. Z. J Neurochem 2007
17932042 OS-9 regulates the transit and polyubiquitination of TRPV4 in the endoplasmic reticulum. External Wang, Y., Fu, X., Gaiser, S., Kottgen, M., Kramer-Zucker, A., Walz, G., Wegierski, T. J Biol Chem 2007
17913834 Association of VASP with TRPC4 in PKG-mediated inhibition of the store-operated calcium response in mesangial cells. External Wang, X., Pluznick, J. L., Settles, D. C., Sansom, S. C. Am J Physiol Renal Physiol 2007
17892531 hTRPC1-associated alpha-actinin, and not hTRPC1 itself, is tyrosine phosphorylated during human platelet activation. External Redondo, P. C., Harper, A. G., Harper, M. T., Brownlow, S. L., Rosado, J. A., Sage, S. O. J Thromb Haemost 2007
17850865 RNF24, a new TRPC interacting protein, causes the intracellular retention of TRPC. External Lussier, M. P., Lepage, P. K., Bousquet, S. M., Boulay, G. Cell Calcium 2008
17699554 Vasopressin-induced membrane trafficking of TRPC3 and AQP2 channels in cells of the rat renal collecting duct. External Goel, M., Sinkins, W. G., Zuo, C. D., Hopfer, U., Schilling, W. P. Am J Physiol Renal Physiol 2007
17684020 Snapin, a new regulator of receptor signaling, augments alpha1A-adrenoceptor-operated calcium influx through TRPC6. External Suzuki, F., Morishima, S., Tanaka, T., Muramatsu, I. J Biol Chem 2007
17681754 Dual role of tubulin-cytoskeleton in store-operated calcium entry in human platelets. External Redondo, P. C., Harper, A. G., Sage, S. O., Rosado, J. A. Cell Signal 2007
17645868 PDZ domain-containing protein as a physiological modulator of TRPV6. External Kim, H. J., Yang, D. K., So, I. Biochem Biophys Res Commun 2007
17636028 TAZ promotes PC2 degradation through a SCFbeta-Trcp E3 ligase complex. External Tian, Y., Kolb, R., Hong, J. H., Carroll, J., Li, D., You, J., Bronson, R., Yaffe, M. B., Zhou, J., Benjamin, T. Mol Cell Biol 2007
17624425 The first ankyrin-like repeat is the minimum indispensable key structure for functional assembly of homo- and heteromeric TRPC4/TRPC5 channels. External Schindl, R., Frischauf, I., Kahr, H., Fritsch, R., Krenn, M., Derndl, A., Vales, E., Muik, M., Derler, I., Groschner, K., Romanin, C. Cell Calcium 2008
17620599 Functional specialization of beta-arrestin interactions revealed by proteomic analysis. External Xiao, K., McClatchy, D. B., Shukla, A. K., Zhao, Y., Chen, M., Shenoy, S. K., Yates, J. R. 3rd, Lefkowitz, R. J. Proc Natl Acad Sci U S A 2007
17486119 STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels. External Yuan, J. P., Zeng, W., Huang, G. N., Worley, P. F., Muallem, S. Nat Cell Biol 2007
17416589 Genetic evidence supporting caveolae microdomain regulation of calcium entry in endothelial cells. External Murata, T., Lin, M. I., Stan, R. V., Bauer, P. M., Yu, J., Sessa, W. C. J Biol Chem 2007
17404231 Regulation of ryanodine receptor-dependent calcium signaling by polycystin-2. External Anyatonwu, G. I., Estrada, M., Tian, X., Somlo, S., Ehrlich, B. E. Proc Natl Acad Sci U S A 2007
17360584 Orai proteins interact with TRPC channels and confer responsiveness to store depletion. External Liao, Y., Erxleben, C., Yildirim, E., Abramowitz, J., Armstrong, D. L., Birnbaumer, L. Proc Natl Acad Sci U S A 2007
17298389 Identification and characterisation of novel tubulin-binding motifs located within the C-terminus of TRPV1. External Goswami, C., Hucho, T. B., Hucho, F. J Neurochem 2007
17283055 Fibrocystin/polyductin, found in the same protein complex with polycystin-2, regulates calcium responses in kidney epithelia. External Wang, S., Zhang, J., Nauli, S. M., Li, X., Starremans, P. G., Luo, Y., Roberts, K. A., Zhou, J. Mol Cell Biol 2007
17251321 Regulation of TRP channel TRPM2 by the tyrosine phosphatase PTPL1. External Zhang, W., Tong, Q., Conrad, K., Wozney, J., Cheung, J. Y., Miller, B. A. Am J Physiol Cell Physiol 2007
17224452 Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx. Evidence for similarities in store-operated and calcium release-activated calcium channel components. External Ong, H. L., Cheng, K. T., Liu, X., Bandyopadhyay, B. C., Paria, B. C., Soboloff, J., Pani, B., Gwack, Y., Srikanth, S., Singh, B. B., Gill, D. L., Ambudkar, I. S. J Biol Chem 2007
17202249 Regulation of capacitative calcium entries by alpha1-syntrophin: association of TRPC1 with dystrophin complex and the PDZ domain of alpha1-syntrophin. External Vandebrouck, A., Sabourin, J., Rivet, J., Balghi, H., Sebille, S., Kitzis, A., Raymond, G., Cognard, C., Bourmeyster, N., Constantin, B. FASEB J 2007
17197020 Identification of tyrosines in the putative regulatory site of the Ca2+ channel TRPV6. External Sternfeld, L., Anderie, I., Schmid, A., Al-Shaldi, H., Krause, E., Magg, T., Schreiner, D., Hofer, H. W., Schulz, I. Cell Calcium 2007
17194758 Cyclin-dependent kinase 5 modulates nociceptive signaling through direct phosphorylation of transient receptor potential vanilloid 1. External Pareek, T. K., Keller, J., Kesavapany, S., Agarwal, N., Kuner, R., Pant, H. C., Iadarola, M. J., Brady, R. O., Kulkarni, A. B. Proc Natl Acad Sci U S A 2007
17156765 Insulin potentiates TRPC3-mediated cation currents in normal but not in insulin-resistant mouse cardiomyocytes. External Fauconnier, J., Lanner, J. T., Sultan, A., Zhang, S. J., Katz, A., Bruton, J. D., Westerblad, H. Cardiovasc Res 2007
17129578 Phospholipase C-dependent control of cardiac calcium homeostasis involves a TRPC3-NCX1 signaling complex. External Eder, P., Probst, D., Rosker, C., Poteser, M., Wolinski, H., Kohlwein, S. D., Romanin, C., Groschner, K. Cardiovasc Res 2007
17110928 The HECT ubiquitin ligase AIP4 regulates the cell surface expression of select TRP channels. External Wegierski, T., Hill, K., Schaefer, M., Walz, G. EMBO J 2006
17088214 The TRPM7 ion channel functions in cholinergic synaptic vesicles and affects transmitter release. External Krapivinsky, G., Mochida, S., Krapivinsky, L., Cibulsky, S. M., Clapham, D. E. Neuron 2006
17074976 Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane. External Stein, A. T., Ufret-Vincenty, C. A., Hua, L., Santana, L. F., Gordon, S. E. J Gen Physiol 2006
17012351 TRPC3 channels colocalize with Na+/Ca2+ exchanger and Na+ pump in axial component of transverse-axial tubular system of rat ventricle. External Goel, M., Zuo, C. D., Sinkins, W. G., Schilling, W. P. Am J Physiol Heart Circ Physiol 2007
17008358 Kinesin-2 mediates physical and functional interactions between polycystin-2 and fibrocystin. External Wu, Y., Dai, X. Q., Li, Q., Chen, C. X., Mai, W., Hussain, Z., Long, W., Montalbetti, N., Li, G., Glynne, R., Wang, S., Cantiello, H. F., Wu, G., Chen, X. Z. Hum Mol Genet 2006
16959851 Dynamic but not constitutive association of calmodulin with rat TRPV6 channels enables fine tuning of Ca2+-dependent inactivation. External Derler, I., Hofbauer, M., Kahr, H., Fritsch, R., Muik, M., Kepplinger, K., Hack, M. E., Moritz, S., Schindl, R., Groschner, K., Romanin, C. J Physiol 2006
16950792 Polycystin-2 cation channel function is under the control of microtubular structures in primary cilia of renal epithelial cells. External Li, Q., Montalbetti, N., Wu, Y., Ramos, A., Raychowdhury, M. K., Chen, X. Z., Cantiello, H. F. J Biol Chem 2006
16916799 Identification of two domains involved in the assembly of transient receptor potential canonical channels. External Lepage, P. K., Lussier, M. P., Barajas-Martinez, H., Bousquet, S. M., Blanchard, A. P., Francoeur, N., Dumaine, R., Boulay, G. J Biol Chem 2006
16906149 STIM1 carboxyl-terminus activates native SOC, I(crac) and TRPC1 channels. External Huang, G. N., Zeng, W., Kim, J. Y., Yuan, J. P., Han, L., Muallem, S., Worley, P. F. Nat Cell Biol 2006
16905188 Signaling proteins in raft-like microdomains are essential for Ca2+ wave propagation in glial cells. External Weerth, S. H., Holtzclaw, L. A., Russell, J. T. Cell Calcium 2007
16899571 Pregnancy-enhanced store-operated Ca2+ channel function in uterine artery endothelial cells is associated with enhanced agonist-specific transient receptor potential channel 3-inositol 1,4,5-trisphosphate receptor 2 interaction. External Gifford, S. M., Yi, F. X., Bird, I. M. J Endocrinol 2006
16895908 RGS2 inhibits the epithelial Ca2+ channel TRPV6. External Schoeber, J. P., Topala, C. N., Wang, X., Diepens, R. J., Lambers, T. T., Hoenderop, J. G., Bindels, R. J. J Biol Chem 2006
16891422 Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor. External Ishimaru, Y., Inada, H., Kubota, M., Zhuang, H., Tominaga, M., Matsunami, H. Proc Natl Acad Sci U S A 2006
16887806 Homer 1 mediates store- and inositol 1,4,5-trisphosphate receptor-dependent translocation and retrieval of TRPC3 to the plasma membrane. External Kim, J. Y., Zeng, W., Kiselyov, K., Yuan, J. P., Dehoff, M. H., Mikoshiba, K., Worley, P. F., Muallem, S. J Biol Chem 2006
16875688 Identification and characterization of GSRP-56, a novel Golgi-localized spectrin repeat-containing protein. External Kobayashi, Y., Katanosaka, Y., Iwata, Y., Matsuoka, M., Shigekawa, M., Wakabayashi, S. Exp Cell Res 2006
16870612 Interaction of STIM1 with endogenously expressed human canonical TRP1 upon depletion of intracellular Ca2+ stores. External Lopez, J. J., Salido, G. M., Pariente, J. A., Rosado, J. A. J Biol Chem 2006
16822931 Caveolin-1 regulates store-operated Ca2+ influx by binding of its scaffolding domain to transient receptor potential channel-1 in endothelial cells. External Kwiatek, A. M., Minshall, R. D., Cool, D. R., Skidgel, R. A., Malik, A. B., Tiruppathi, C. Mol Pharmacol 2006
16818374 Interaction between TRPC channel subunits in endothelial cells. External Antoniotti, S., Fiorio Pla, A., Barral, S., Scalabrino, O., Munaron, L., Lovisolo, D. J Recept Signal Transduct Res 2006
16763551 Calbindin-D28K dynamically controls TRPV5-mediated Ca2+ transport. External Lambers, T. T., Mahieu, F., Oancea, E., Hoofd, L., de Lange, F., Mensenkamp, A. R., Voets, T., Nilius, B., Clapham, D. E., Hoenderop, J. G., Bindels, R. J. EMBO J 2006
16627472 PACSINs bind to the TRPV4 cation channel. PACSIN 3 modulates the subcellular localization of TRPV4. External Cuajungco, M. P., Grimm, C., Oshima, K., D'hoedt, D., Nilius, B., Mensenkamp, A. R., Bindels, R. J., Plomann, M., Heller, S. J Biol Chem 2006
16609150 More than colocalizing with polycystin-1, polycystin-L is in the centrosome. External Bui-Xuan, E. F., Li, Q., Chen, X. Z., Boucher, C. A., Sandford, R., Zhou, J., Basora, N. Am J Physiol Renal Physiol 2006
16606612 Lysosomal localization of TRPML3 depends on TRPML2 and the mucolipidosis-associated protein TRPML1. External Venkatachalam, K., Hofmann, T., Montell, C. J Biol Chem 2006
16571723 A role for AQP5 in activation of TRPV4 by hypotonicity: concerted involvement of AQP5 and TRPV4 in regulation of cell volume recovery. External Liu, X., Bandyopadhyay, B. C., Nakamoto, T., Singh, B., Liedtke, W., Melvin, J. E., Ambudkar, I. J Biol Chem 2006
16565876 Interaction of the epithelial Ca2+ channels TRPV5 and TRPV6 with the intestine- and kidney-enriched PDZ protein NHERF4. External van de Graaf, S. F., Hoenderop, J. G., van der Kemp, A. W., Gisler, S. M., Bindels, R. J. Pflugers Arch 2006
16537542 TRPC3 and TRPC4 associate to form a redox-sensitive cation channel. Evidence for expression of native TRPC3-TRPC4 heteromeric channels in endothelial cells. External Poteser, M., Graziani, A., Rosker, C., Eder, P., Derler, I., Kahr, H., Zhu, M. X., Romanin, C., Groschner, K. J Biol Chem 2006
16510717 TRPV1 recapitulates native capsaicin receptor in sensory neurons in association with Fas-associated factor 1. External Kim, S., Kang, C., Shin, C. Y., Hwang, S. W., Yang, Y. D., Shim, W. S., Park, M. Y., Kim, E., Kim, M., Kim, B. M., Cho, H., Shin, Y., Oh, U. J Neurosci 2006
16500902 Structural characterization of the split pleckstrin homology domain in phospholipase C-gamma1 and its interaction with TRPC3. External Wen, W., Yan, J., Zhang, M. J Biol Chem 2006
16500080 TRPA1 is a substrate for de-ubiquitination by the tumor suppressor CYLD. External Stokes, A., Wakano, C., Koblan-Huberson, M., Adra, C. N., Fleig, A., Turner, H. Cell Signal 2006
16469785 Calcium-sensing mechanism in TRPC5 channels contributing to retardation of neurite outgrowth. External Hui, H., McHugh, D., Hannan, M., Zeng, F., Xu, S. Z., Khan, S. U., Levenson, R., Beech, D. J., Weiss, J. L. J Physiol 2006
16461353 Regulation of the transient receptor potential channel TRPM2 by the Ca2+ sensor calmodulin. External Tong, Q., Zhang, W., Conrad, K., Mostoller, K., Cheung, J. Y., Peterson, B. Z., Miller, B. A. J Biol Chem 2006
16418302 Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. External Sours, S., Du, J., Chu, S., Ding, M., Zhou, X. J., Ma, R. Am J Physiol Renal Physiol 2006
16407977 TRPM7, a novel regulator of actomyosin contractility and cell adhesion. External Clark, K., Langeslag, M., van Leeuwen, B., Ran, L., Ryazanov, A. G., Figdor, C. G., Moolenaar, W. H., Jalink, K., van Leeuwen, F. N. EMBO J 2006
16407161 Role of Src in C3 transient receptor potential channel function and evidence for a heterogeneous makeup of receptor- and store-operated Ca2+ entry channels. External Kawasaki, B. T., Liao, Y., Birnbaumer, L. Proc Natl Acad Sci U S A 2006
16380433 Identification of BSPRY as a novel auxiliary protein inhibiting TRPV5 activity. External van de Graaf, S. F., van der Kemp, A. W., van den Berg, D., van Oorschot, M., Hoenderop, J. G., Bindels, R. J. J Am Soc Nephrol 2006
16354700 Direct interaction with Rab11a targets the epithelial Ca2+ channels TRPV5 and TRPV6 to the plasma membrane. External van de Graaf, S. F., Chang, Q., Mensenkamp, A. R., Hoenderop, J. G., Bindels, R. J. Mol Cell Biol 2006
16352746 The immunophilin FKBP52 inhibits the activity of the epithelial Ca2+ channel TRPV5. External Gkika, D., Topala, C. N., Hoenderop, J. G., Bindels, R. J. Am J Physiol Renal Physiol 2006
16319926 NGF rapidly increases membrane expression of TRPV1 heat-gated ion channels. External Zhang, X., Huang, J., McNaughton, P. A. EMBO J 2005
16311606 Polycystin-1 and polycystin-2 regulate the cell cycle through the helix-loop-helix inhibitor Id2. External Li, X., Luo, Y., Starremans, P. G., McNamara, C. A., Pei, Y., Zhou, J. Nat Cell Biol 2005
16270640 Transient receptor potential protein subunit assembly and membrane distribution in human platelets. External Brownlow, S. L., Sage, S. O. Thromb Haemost 2005
16254212 Activation of the endothelial store-operated ISOC Ca2+ channel requires interaction of protein 4.1 with TRPC4. External Cioffi, D. L., Wu, S., Alexeyev, M., Goodman, S. R., Zhu, M. X., Stevens, T. Circ Res 2005
16239475 The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel. External Chang, Q., Hoefs, S., van der Kemp, A. W., Topala, C. N., Bindels, R. J., Hoenderop, J. G. Science 2005
16237318 Heteromerization and colocalization of TrpV1 and TrpV2 in mammalian cell lines and rat dorsal root ganglia. External Rutter, A. R., Ma, Q. P., Leveridge, M., Bonnert, T. P. Neuroreport 2005
16223735 Polycystin 2 interacts with type I inositol 1,4,5-trisphosphate receptor to modulate intracellular Ca2+ signaling. External Li, Y., Wright, J. M., Qian, F., Germino, G. G., Guggino, W. B. J Biol Chem 2005
16189514 Towards a proteome-scale map of the human protein-protein interaction network. External Rual, J. F., Venkatesan, K., Hao, T., Hirozane-Kishikawa, T., Dricot, A., Li, N., Berriz, G. F., Gibbons, F. D., Dreze, M., Ayivi-Guedehoussou, N., Klitgord, N., Simon, C., Boxem, M., Milstein, S., Rosenberg, J., Goldberg, D. S., Zhang, L. V., Wong, S. L., Franklin, G., Li, S., Albala, J. S., Lim, J., Fraughton, C., Llamosas, E., Cevik, S., Bex, C., Lamesch, P., Sikorski, R. S., Vandenhaute, J., Zoghbi, H. Y., Smolyar, A., Bosak, S., Sequerra, R., Doucette-Stamm, L., Cusick, M. E., Hill, D. E., Roth, F. P., Vidal, M. Nature 2005
16169070 A human protein-protein interaction network: a resource for annotating the proteome. External Stelzl, U., Worm, U., Lalowski, M., Haenig, C., Brembeck, F. H., Goehler, H., Stroedicke, M., Zenkner, M., Schoenherr, A., Koeppen, S., Timm, J., Mintzlaff, S., Abraham, C., Bock, N., Kietzmann, S., Goedde, A., Toksoz, E., Droege, A., Krobitsch, S., Korn, B., Birchmeier, W., Lehrach, H., Wanker, E. E. Cell 2005
16153633 Junctate, an inositol 1,4,5-triphosphate receptor associated protein, is present in rodent sperm and binds TRPC2 and TRPC5 but not TRPC1 channels. External Stamboulian, S., Moutin, M. J., Treves, S., Pochon, N., Grunwald, D., Zorzato, F., De Waard, M., Ronjat, M., Arnoult, C. Dev Biol 2005
16144838 Epidermal growth factor induces tyrosine phosphorylation, membrane insertion, and activation of transient receptor potential channel 4. External Odell, A. F., Scott, J. L., Van Helden, D. F. J Biol Chem 2005
16135816 PKD2 functions as an epidermal growth factor-activated plasma membrane channel. External Ma, R., Li, W. P., Rundle, D., Kong, J., Akbarali, H. I., Tsiokas, L. Mol Cell Biol 2005
16115206 Extensive co-localization and heteromultimer formation of the vanilloid receptor-like protein TRPV2 and the capsaicin receptor TRPV1 in the adult rat cerebral cortex. External Liapi, A., Wood, J. N. Eur J Neurosci 2005
16025302 Proteomic analysis of TRPC5- and TRPC6-binding partners reveals interaction with the plasmalemmal Na(+)/K(+)-ATPase. External Goel, M., Sinkins, W., Keightley, A., Kinter, M., Schilling, W. P. Pflugers Arch 2005
15994335 Activation of M1 muscarinic acetylcholine receptors stimulates the formation of a multiprotein complex centered on TRPC6 channels. External Kim, J. Y., Saffen, D. J Biol Chem 2005
15987684 Calmodulin and calcium interplay in the modulation of TRPC5 channel activity. Identification of a novel C-terminal domain for calcium/calmodulin-mediated facilitation. External Ordaz, B., Tang, J., Xiao, R., Salgado, A., Sampieri, A., Zhu, M. X., Vaca, L. J Biol Chem 2005
15972814 Endogenous TRPC1, TRPC3, and TRPC7 proteins combine to form native store-operated channels in HEK-293 cells. External Zagranichnaya, T. K., Wu, X., Villereal, M. L. J Biol Chem 2005
15935109 Plasma membrane localization and function of TRPC1 is dependent on its interaction with beta-tubulin in retinal epithelium cells. External Bollimuntha, S., Cornatzer, E., Singh, B. B. Vis Neurosci 2005
15924139 TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function. External Reiser, J., Polu, K. R., Moller, C. C., Kenlan, P., Altintas, M. M., Wei, C., Faul, C., Herbert, S., Villegas, I., Avila-Casado, C., McGee, M., Sugimoto, H., Brown, D., Kalluri, R., Mundel, P., Smith, P. L., Clapham, D. E., Pollak, M. R. Nat Genet 2005
15895247 Inhibition of TRPC5 channels by Ca2+-binding protein 1 in Xenopus oocytes. External Kinoshita-Kawada, M., Tang, J., Xiao, R., Kaneko, S., Foskett, J. K., Zhu, M. X. Pflugers Arch 2005
15894168 Tyrosine phosphatase PTP1B interacts with TRPV6 in vivo and plays a role in TRPV6-mediated calcium influx in HEK293 cells. External Sternfeld, L., Krause, E., Schmid, A., Anderie, I., Latas, A., Al-Shaldi, H., Kohl, A., Evers, K., Hofer, H. W., Schulz, I. Cell Signal 2005
15883036 Identification of a protein that interacts with the vanilloid receptor. External Lee, S. Y. Biochem Biophys Res Commun 2005
15843396 Alpha-actinin associates with polycystin-2 and regulates its channel activity. External Li, Q., Montalbetti, N., Shen, P. Y., Dai, X. Q., Cheeseman, C. I., Karpinski, E., Wu, G., Cantiello, H. F., Chen, X. Z. Hum Mol Genet 2005
15834157 Molecular analysis of a store-operated and 2-acetyl-sn-glycerol-sensitive non-selective cation channel. Heteromeric assembly of TRPC1-TRPC3. External Liu, X., Bandyopadhyay, B. C., Singh, B. B., Groschner, K., Ambudkar, I. S. J Biol Chem 2005
15758179 Canonical transient receptor potential 1 plays a role in basic fibroblast growth factor (bFGF)/FGF receptor-1-induced Ca2+ entry and embryonic rat neural stem cell proliferation. External Fiorio Pla, A., Maric, D., Brazer, S. C., Giacobini, P., Liu, X., Chang, Y. H., Ambudkar, I. S., Barker, J. L. J Neurosci 2005
15757897 MxA, a member of the dynamin superfamily, interacts with the ankyrin-like repeat domain of TRPC. External Lussier, M. P., Cayouette, S., Lepage, P. K., Bernier, C. L., Francoeur, N., St-Hilaire, M., Pinard, M., Boulay, G. J Biol Chem 2005
15744307 Phospholipase Cgamma1 controls surface expression of TRPC3 through an intermolecular PH domain. External van Rossum, D. B., Patterson, R. L., Sharma, S., Barrow, R. K., Kornberg, M., Gill, D. L., Snyder, S. H. Nature 2005
15713749 Homo- and heteromeric assembly of TRPV channel subunits. External Hellwig, N., Albrecht, N., Harteneck, C., Schultz, G., Schaefer, M. J Cell Sci 2005
15692563 Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation. External Kottgen, M., Benzing, T., Simmen, T., Tauber, R., Buchholz, B., Feliciangeli, S., Huber, T. B., Schermer, B., Kramer-Zucker, A., Hopker, K., Simmen, K. C., Tschucke, C. C., Sandford, R., Kim, E., Thomas, G., Walz, G. EMBO J 2005
15665527 Requirement of PDZ domains for the stimulation of the epithelial Ca2+ channel TRPV5 by the NHE regulating factor NHERF2 and the serum and glucocorticoid inducible kinase SGK1. External Palmada, M., Poppendieck, S., Embark, H. M., van de Graaf, S. F., Boehmer, C., Bindels, R. J., Lang, F. Cell Physiol Biochem 2005
15654973 Phospholipase cgamma1 is required for activation of store-operated channels in human keratinocytes. External Tu, C. L., Chang, W., Bikle, D. D. J Invest Dermatol 2005
15623527 Apical localization of a functional TRPC3/TRPC6-Ca2+-signaling complex in polarized epithelial cells. Role in apical Ca2+ influx. External Bandyopadhyay, B. C., Swaim, W. D., Liu, X., Redman, R. S., Patterson, R. L., Ambudkar, I. S. J Biol Chem 2005
15590898 Expression of TRPC4 channel protein that interacts with NHERF-2 in rat descending vasa recta. External Lee-Kwon, W., Wade, J. B., Zhang, Z., Pallone, T. L., Weinman, E. J. Am J Physiol Cell Physiol 2005
15590641 Regulation of the Ca2+ sensitivity of the nonselective cation channel TRPM4. External Nilius, B., Prenen, J., Tang, J., Wang, C., Owsianik, G., Janssens, A., Voets, T., Zhu, M. X. J Biol Chem 2005
15569253 Identification and characterization of a Ca2+ -sensitive interaction of the vanilloid receptor TRPV1 with tubulin. External Goswami, C., Dreger, M., Jahnel, R., Bogen, O., Gillen, C., Hucho, F. J Neurochem 2004
15548533 Genomic organization and functional analysis of murine PKD2L1. External Murakami, M., Ohba, T., Xu, F., Shida, S., Satoh, E., Ono, K., Miyoshi, I., Watanabe, H., Ito, H., Iijima, T. J Biol Chem 2005
15547947 Formation of a physiological complex between TRPV2 and RGA protein promotes cell surface expression of TRPV2. External Stokes, A. J., Wakano, C., Del Carmen, K. A., Koblan-Huberson, M., Turner, H. J Cell Biochem 2005
15540229 Canonical transient receptor potential channel 4 (TRPC4) co-localizes with the scaffolding protein ZO-1 in human fetal astrocytes in culture. External Song, X., Zhao, Y., Narcisse, L., Duffy, H., Kress, Y., Lee, S., Brosnan, C. F. Glia 2005
15537648 Orexin-A-induced Ca2+ entry: evidence for involvement of trpc channels and protein kinase C regulation. External Larsson, K. P., Peltonen, H. M., Bart, G., Louhivuori, L. M., Penttonen, A., Antikainen, M., Kukkonen, J. P., Akerman, K. E. J Biol Chem 2005
15485879 Phosphorylation of annexin I by TRPM7 channel-kinase. External Dorovkov, M. V., Ryazanov, A. G. J Biol Chem 2004
15471852 Interaction between protein kinase Cmu and the vanilloid receptor type 1. External Wang, Y., Kedei, N., Wang, M., Wang, Q. J., Huppler, A. R., Toth, A., Tran, R., Blumberg, P. M. J Biol Chem 2004
15385169 Enkurin is a novel calmodulin and TRPC channel binding protein in sperm. External Sutton, K. A., Jungnickel, M. K., Wang, Y., Cullen, K., Lambert, S., Florman, H. M. Dev Biol 2004
15337773 Pericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assembly. External Jurczyk, A., Gromley, A., Redick, S., San Agustin, J., Witman, G., Pazour, G. J., Peters, D. J., Doxsey, S. J Cell Biol 2004
15329338 Erythropoietin-modulated calcium influx through TRPC2 is mediated by phospholipase Cgamma and IP3R. External Tong, Q., Chu, X., Cheung, J. Y., Conrad, K., Stahl, R., Barber, D. L., Mignery, G., Miller, B. A. Am J Physiol Cell Physiol 2004
15327778 VAMP2-dependent exocytosis regulates plasma membrane insertion of TRPC3 channels and contributes to agonist-stimulated Ca2+ influx. External Singh, B. B., Lockwich, T. P., Bandyopadhyay, B. C., Liu, X., Bollimuntha, S., Brazer, S. C., Combs, C., Das, S., Leenders, A. G., Sheng, Z. H., Knepper, M. A., Ambudkar, S. V., Ambudkar, I. S. Mol Cell 2004
15302852 Junctate is a key element in calcium entry induced by activation of InsP3 receptors and/or calcium store depletion. External Treves, S., Franzini-Armstrong, C., Moccagatta, L., Arnoult, C., Grasso, C., Schrum, A., Ducreux, S., Zhu, M. X., Mikoshiba, K., Girard, T., Smida-Rezgui, S., Ronjat, M., Zorzato, F. J Cell Biol 2004
15249591 A TRPV2-PKA signaling module for transduction of physical stimuli in mast cells. External Stokes, A. J., Shimoda, L. M., Koblan-Huberson, M., Adra, C. N., Turner, H. J Exp Med 2004
15199065 Association of immunophilins with mammalian TRPC channels. External Sinkins, W. G., Goel, M., Estacion, M., Schilling, W. P. J Biol Chem 2004
15194699 PIGEA-14, a novel coiled-coil protein affecting the intracellular distribution of polycystin-2. External Hidaka, S., Konecke, V., Osten, L., Witzgall, R. J Biol Chem 2004
15188402 Proteins associated with type II bone morphogenetic protein receptor (BMPR-II) and identified by two-dimensional gel electrophoresis and mass spectrometry. External Hassel, S., Eichner, A., Yakymovych, M., Hellman, U., Knaus, P., Souchelnytskyi, S. Proteomics 2004
15123714 PKD2 interacts and co-localizes with mDia1 to mitotic spindles of dividing cells: role of mDia1 IN PKD2 localization to mitotic spindles. External Rundle, D. R., Gorbsky, G., Tsiokas, L. J Biol Chem 2004
15123711 Regulation of the mouse epithelial Ca2(+) channel TRPV6 by the Ca(2+)-sensor calmodulin. External Lambers, T. T., Weidema, A. F., Nilius, B., Hoenderop, J. G., Bindels, R. J. J Biol Chem 2004
15121806 A role for SNAP-25 but not VAMPs in store-mediated Ca2+ entry in human platelets. External Redondo, P. C., Harper, A. G., Salido, G. M., Pariente, J. A., Sage, S. O., Rosado, J. A. J Physiol 2004
15104175 TRPC channel interactions with calmodulin and IP3 receptors. External Zhu, M. X., Tang, J. Novartis Found Symp 2004
15100231 80K-H as a new Ca2+ sensor regulating the activity of the epithelial Ca2+ channel transient receptor potential cation channel V5 (TRPV5). External Gkika, D., Mahieu, F., Nilius, B., Hoenderop, J. G., Bindels, R. J. J Biol Chem 2004
15084474 Modulation of TRPV1 by nonreceptor tyrosine kinase, c-Src kinase. External Jin, X., Morsy, N., Winston, J., Pasricha, P. J., Garrett, K., Akbarali, H. I. Am J Physiol Cell Physiol 2004
15066994 Regulated exocytosis contributes to protein kinase C potentiation of vanilloid receptor activity. External Morenilla-Palao, C., Planells-Cases, R., Garcia-Sanz, N., Ferrer-Montiel, A. J Biol Chem 2004
15060061 The N-terminal extracellular domain is required for polycystin-1-dependent channel activity. External Babich, V., Zeng, W. Z., Yeh, B. I., Ibraghimov-Beskrovnaya, O., Cai, Y., Somlo, S., Huang, C. L. J Biol Chem 2004
14991772 RGA protein associates with a TRPV ion channel during biosynthesis and trafficking. External Barnhill, J. C., Stokes, A. J., Koblan-Huberson, M., Shimoda, L. M., Muraguchi, A., Adra, C. N., Turner, H. J Cell Biochem 2004
14983059 Regulation of canonical transient receptor potential isoform 3 (TRPC3) channel by protein kinase G. External Kwan, H. Y., Huang, Y., Yao, X. Proc Natl Acad Sci U S A 2004
14976260 Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia. External Chubanov, V., Waldegger, S., Mederos y Schnitzler, M., Vitzthum, H., Sassen, M. C., Seyberth, H. W., Konrad, M., Gudermann, T. Proc Natl Acad Sci U S A 2004
14761972 Regulation of TRPC6 channel activity by tyrosine phosphorylation. External Hisatsune, C., Kuroda, Y., Nakamura, K., Inoue, T., Nakamura, T., Michikawa, T., Mizutani, A., Mikoshiba, K. J Biol Chem 2004
14736881 Ca(2+) signaling by TRPC3 involves Na(+) entry and local coupling to the Na(+)/Ca(2+) exchanger. External Rosker, C., Graziani, A., Lukas, M., Eder, P., Zhu, M. X., Romanin, C., Groschner, K. J Biol Chem 2004
14699131 Interaction of TRPC2 and TRPC6 in erythropoietin modulation of calcium influx. External Chu, X., Tong, Q., Cheung, J. Y., Wozney, J., Conrad, K., Mazack, V., Zhang, W., Stahl, R., Barber, D. L., Miller, B. A. J Biol Chem 2004
14699077 Ca2+/calmodulin modulates TRPV1 activation by capsaicin. External Rosenbaum, T., Gordon-Shaag, A., Munari, M., Gordon, S. E. J Gen Physiol 2004
14614461 Activation of the TRPC1 cation channel by metabotropic glutamate receptor mGluR1. External Kim, S. J., Kim, Y. S., Yuan, J. P., Petralia, R. S., Worley, P. F., Linden, D. J. Nature 2003
14551243 Cholesterol depletion impairs vascular reactivity to endothelin-1 by reducing store-operated Ca2+ entry dependent on TRPC1. External Bergdahl, A., Gomez, M. F., Dreja, K., Xu, S. Z., Adner, M., Beech, D. J., Broman, J., Hellstrand, P., Sward, K. Circ Res 2003
14530267 Inhibitor of myogenic family, a novel suppressor of store-operated currents through an interaction with TRPC1. External Ma, R., Rundle, D., Jacks, J., Koch, M., Downs, T., Tsiokas, L. J Biol Chem 2003
14523239 Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1). External Bhave, G., Hu, H. J., Glauner, K. S., Zhu, W., Wang, H., Brasier, D. J., Oxford, G. S., Gereau, R. W. 4th Proc Natl Acad Sci U S A 2003
14517216 Microtubule-associated [corrected] protein 7 increases the membrane expression of transient receptor potential vanilloid 4 (TRPV4). External Suzuki, M., Hirao, A., Mizuno, A. J Biol Chem 2003
14505576 Homer binds TRPC family channels and is required for gating of TRPC1 by IP3 receptors. External Yuan, J. P., Kiselyov, K., Shin, D. M., Chen, J., Shcheynikov, N., Kang, S. H., Dehoff, M. H., Schwarz, M. K., Seeburg, P. H., Muallem, S., Worley, P. F. Cell 2003
12970180 Amplification of receptor signalling by Ca2+ entry-mediated translocation and activation of PLCgamma2 in B lymphocytes. External Nishida, M., Sugimoto, K., Hara, Y., Mori, E., Morii, T., Kurosaki, T., Mori, Y. EMBO J 2003
12937304 Analysis of the polycystins in aortic vascular smooth muscle cells. External Qian, Q., Li, M., Cai, Y., Ward, C. J., Somlo, S., Harris, P. C., Torres, V. E. J Am Soc Nephrol 2003
12858178 TRPC5 is a regulator of hippocampal neurite length and growth cone morphology. External Greka, A., Navarro, B., Oancea, E., Duggan, A., Clapham, D. E. Nat Neurosci 2003
12857742 Formation of novel TRPC channels by complex subunit interactions in embryonic brain. External Strubing, C., Krapivinsky, G., Krapivinsky, L., Clapham, D. E. J Biol Chem 2003
12840011 Polycystin-1 distribution is modulated by polycystin-2 expression in mammalian cells. External Grimm, D. H., Cai, Y., Chauvet, V., Rajendran, V., Zeltner, R., Geng, L., Avner, E. D., Sweeney, W., Somlo, S., Caplan, M. J. J Biol Chem 2003
12809519 Troponin I binds polycystin-L and inhibits its calcium-induced channel activation. External Li, Q., Liu, Y., Shen, P. Y., Dai, X. Q., Wang, S., Smillie, L. B., Sandford, R., Chen, X. Z. Biochemistry 2003
12808128 Structural determinant of TRPV1 desensitization interacts with calmodulin. External Numazaki, M., Tominaga, T., Takeuchi, K., Murayama, N., Toyooka, H., Tominaga, M. Proc Natl Acad Sci U S A 2003
12766172 RhoA interaction with inositol 1,4,5-trisphosphate receptor and transient receptor potential channel-1 regulates Ca2+ entry. Role in signaling increased endothelial permeability. External Mehta, D., Ahmmed, G. U., Paria, B. C., Holinstat, M., Voyno-Yasenetskaya, T., Tiruppathi, C., Minshall, R. D., Malik, A. B. J Biol Chem 2003
12765696 The TRPV6 gene, cDNA and protein. External Hirnet, D., Olausson, J., Fecher-Trost, C., Bodding, M., Nastainczyk, W., Wissenbach, U., Flockerzi, V., Freichel, M. Cell Calcium 2003
12732636 Caveolin-1 contributes to assembly of store-operated Ca2+ influx channels by regulating plasma membrane localization of TRPC1. External Brazer, S. C., Singh, B. B., Liu, X., Swaim, W., Ambudkar, I. S. J Biol Chem 2003
12724311 Ca2+-dependent potentiation of the nonselective cation channel TRPV4 is mediated by a C-terminal calmodulin binding site. External Strotmann, R., Schultz, G., Plant, T. D. J Biol Chem 2003
12660155 Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex. External van de Graaf, S. F., Hoenderop, J. G., Gkika, D., Lamers, D., Prenen, J., Rescher, U., Gerke, V., Staub, O., Nilius, B., Bindels, R. J. EMBO J 2003
12601176 The mouse C-type transient receptor potential 2 (TRPC2) channel: alternative splicing and calmodulin binding to its N terminus. External Yildirim, E., Dietrich, A., Birnbaumer, L. Proc Natl Acad Sci U S A 2003
12574114 Homo- and heterotetrameric architecture of the epithelial Ca2+ channels TRPV5 and TRPV6. External Hoenderop, J. G., Voets, T., Hoefs, S., Weidema, F., Prenen, J., Nilius, B., Bindels, R. J. EMBO J 2003
12538589 Regulation of a transient receptor potential (TRP) channel by tyrosine phosphorylation. SRC family kinase-dependent tyrosine phosphorylation of TRPV4 on TYR-253 mediates its response to hypotonic stress. External Xu, H., Zhao, H., Tian, W., Yoshida, K., Roullet, J. B., Cohen, D. M. J Biol Chem 2003
12527301 Polycystin-2 associates with tropomyosin-1, an actin microfilament component. External Li, Q., Dai, Y., Guo, L., Liu, Y., Hao, C., Wu, G., Basora, N., Michalak, M., Chen, X. Z. J Mol Biol 2003
12525172 Polycystin-2 interacts with troponin I, an angiogenesis inhibitor. External Li, Q., Shen, P. Y., Wu, G., Chen, X. Z. Biochemistry 2003
12472899 Type-specific inositol 1,4,5-trisphosphate receptor localization in the vomeronasal organ and its interaction with a transient receptor potential channel, TRPC2. External Brann, J. H., Dennis, J. C., Morrison, E. E., Fadool, D. A. J Neurochem 2002
12437926 Phospholipase C-gamma is required for agonist-induced Ca2+ entry. External Patterson, R. L., van Rossum, D. B., Ford, D. L., Hurt, K. J., Bae, S. S., Suh, P. G., Kurosaki, T., Snyder, S. H., Gill, D. L. Cell 2002
12379180 Ca(2+)-calmodulin regulates receptor-operated Ca(2+) entry activity of TRPC6 in HEK-293 cells. External Boulay, G. Cell Calcium 2002
12377790 Selective association of TRPC channel subunits in rat brain synaptosomes. External Goel, M., Sinkins, W. G., Schilling, W. P. J Biol Chem 2002
12196544 Endogenously expressed Trp1 is involved in store-mediated Ca2+ entry by conformational coupling in human platelets. External Rosado, J. A., Brownlow, S. L., Sage, S. O. J Biol Chem 2002
12194871 cAMP-dependent protein kinase regulates desensitization of the capsaicin receptor (VR1) by direct phosphorylation. External Bhave, G., Zhu, W., Wang, H., Brasier, D. J., Oxford, G. S., Gereau, R. W. 4th Neuron 2002
12167663 Erythropoietin modulates calcium influx through TRPC2. External Chu, X., Cheung, J. Y., Barber, D. L., Birnbaumer, L., Rothblum, L. I., Conrad, K., Abrasonis, V., Chan, Y. M., Stahl, R., Carey, D. J., Miller, B. A. J Biol Chem 2002
12154080 The PDZ-interacting domain of TRPC4 controls its localization and surface expression in HEK293 cells. External Mery, L., Strauss, B., Dufour, J. F., Krause, K. H., Hoth, M. J Cell Sci 2002
12077606 TRPV3 is a temperature-sensitive vanilloid receptor-like protein. External Smith, G. D., Gunthorpe, M. J., Kelsell, R. E., Hayes, P. D., Reilly, P., Facer, P., Wright, J. E., Jerman, J. C., Walhin, J. P., Ooi, L., Egerton, J., Charles, K. J., Smart, D., Randall, A. D., Anand, P., Davis, J. B. Nature 2002
12032305 Subunit composition of mammalian transient receptor potential channels in living cells. External Hofmann, T., Schaefer, M., Schultz, G., Gudermann, T. Proc Natl Acad Sci U S A 2002
11983166 Calmodulin regulates Ca(2+)-dependent feedback inhibition of store-operated Ca(2+) influx by interaction with a site in the C terminus of TrpC1. External Singh, B. B., Liu, X., Tang, J., Zhu, M. X., Ambudkar, I. S. Mol Cell 2002
11941371 The TRPM7 channel is inactivated by PIP(2) hydrolysis. External Runnels, L. W., Yue, L., Clapham, D. E. Nat Cell Biol 2002
11901144 Identification, characterization, and localization of a novel kidney polycystin-1-polycystin-2 complex. External Newby, L. J., Streets, A. J., Zhao, Y., Harris, P. C., Ward, C. J., Ong, A. C. J Biol Chem 2002
11884385 Direct phosphorylation of capsaicin receptor VR1 by protein kinase Cepsilon and identification of two target serine residues. External Numazaki, M., Tominaga, T., Toyooka, H., Tominaga, M. J Biol Chem 2002
11524429 Stabilization of cortical actin induces internalization of transient receptor potential 3 (Trp3)-associated caveolar Ca2+ signaling complex and loss of Ca2+ influx without disruption of Trp3-inositol trisphosphate receptor association. External Lockwich, T., Singh, B. B., Liu, X., Ambudkar, I. S. J Biol Chem 2001
11418861 Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition. External Chuang, H. H., Prescott, E. D., Kong, H., Shields, S., Jordt, S. E., Basbaum, A. I., Chao, M. V., Julius, D. Nature 2001
11336651 Activation of store-mediated calcium entry by secretion-like coupling between the inositol 1,4,5-trisphosphate receptor type II and human transient receptor potential (hTrp1) channels in human platelets. External Rosado, J. A., Sage, S. O. Biochem J 2001
11311128 The transient receptor potential, TRP4, cation channel is a novel member of the family of calmodulin binding proteins. External Trost, C., Bergs, C., Himmerkus, N., Flockerzi, V. Biochem J 2001
11301024 TRPC1 and TRPC5 form a novel cation channel in mammalian brain. External Strubing, C., Krapivinsky, G., Krapivinsky, L., Clapham, D. E. Neuron 2001
11290752 Identification of common binding sites for calmodulin and inositol 1,4,5-trisphosphate receptors on the carboxyl termini of trp channels. External Tang, J., Lin, Y., Zhang, Z., Tikunova, S., Birnbaumer, L., Zhu, M. X. J Biol Chem 2001
11248124 Competitive regulation of CaT-like-mediated Ca2+ entry by protein kinase C and calmodulin. External Niemeyer, B. A., Bergs, C., Wissenbach, U., Flockerzi, V., Trost, C. Proc Natl Acad Sci U S A 2001
11248050 Activation of Trp3 by inositol 1,4,5-trisphosphate receptors through displacement of inhibitory calmodulin from a common binding domain. External Zhang, Z., Tang, J., Tikunova, S., Johnson, J. D., Chen, Z., Qin, N., Dietrich, A., Stefani, E., Birnbaumer, L., Zhu, M. X. Proc Natl Acad Sci U S A 2001
11163362 Alternative splice variants of hTrp4 differentially interact with the C-terminal portion of the inositol 1,4,5-trisphosphate receptors. External Mery, L., Magnino, F., Schmidt, K., Krause, K. H., Dufour, J. F. FEBS Lett 2001
11161216 TRP-PLIK, a bifunctional protein with kinase and ion channel activities. External Runnels, L. W., Yue, L., Clapham, D. E. Science 2001
11140688 Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents. External Hanaoka, K., Qian, F., Boletta, A., Bhunia, A. K., Piontek, K., Tsiokas, L., Sukhatme, V. P., Guggino, W. B., Germino, G. G. Nature 2000
10983988 Gating of store-operated channels by conformational coupling to ryanodine receptors. External Kiselyov, K. I., Shin, D. M., Wang, Y., Pessah, I. N., Allen, P. D., Muallem, S. Mol Cell 2000
10980202 Association of mammalian trp4 and phospholipase C isozymes with a PDZ domain-containing protein, NHERF. External Tang, Y., Tang, J., Chen, Z., Trost, C., Flockerzi, V., Li, M., Ramesh, V., Zhu, M. X. J Biol Chem 2000
10980191 Expression of truncated transient receptor potential protein 1alpha (Trp1alpha ): evidence that the Trp1 C terminus modulates store-operated Ca2+ entry. External Singh, B. B., Liu, X., Ambudkar, I. S. J Biol Chem 2000
10970773 Coupling between inositol 1,4,5-trisphosphate receptors and human transient receptor potential channel 1 when intracellular Ca2+ stores are depleted. External Rosado, J. A., Sage, S. O. Biochem J 2000
10913159 In vivo interaction of the adapter protein CD2-associated protein with the type 2 polycystic kidney disease protein, polycystin-2. External Lehtonen, S., Ora, A., Olkkonen, V. M., Geng, L., Zerial, M., Somlo, S., Lehtonen, E. J Biol Chem 2000
10882720 Coassembly of Trp1 and Trp3 proteins generates diacylglycerol- and Ca2+-sensitive cation channels. External Lintschinger, B., Balzer-Geldsetzer, M., Baskaran, T., Graier, W. F., Romanin, C., Zhu, M. X., Groschner, K. J Biol Chem 2000
10766822 Assembly of Trp1 in a signaling complex associated with caveolin-scaffolding lipid raft domains. External Lockwich, T. P., Liu, X., Singh, B. B., Jadlowiec, J., Weiland, S., Ambudkar, I. S. J Biol Chem 2000
10760273 The polycystic kidney disease protein PKD2 interacts with Hax-1, a protein associated with the actin cytoskeleton. External Gallagher, A. R., Cedzich, A., Gretz, N., Somlo, S., Witzgall, R. Proc Natl Acad Sci U S A 2000
10677043 Activation of a TRPC3-dependent cation current through the neurotrophin BDNF. External Li, H. S., Xu, X. Z., Montell, C. Neuron 1999
10611319 Modulation of Ca(2+) entry by polypeptides of the inositol 1,4, 5-trisphosphate receptor (IP3R) that bind transient receptor potential (TRP): evidence for roles of TRP and IP3R in store depletion-activated Ca(2+) entry. External Boulay, G., Brown, D. M., Qin, N., Jiang, M., Dietrich, A., Zhu, M. X., Chen, Z., Birnbaumer, M., Mikoshiba, K., Birnbaumer, L. Proc Natl Acad Sci U S A 1999
10518223 The N-terminal domain of the IP3 receptor gates store-operated hTrp3 channels. External Kiselyov, K., Mignery, G. A., Zhu, M. X., Muallem, S. Mol Cell 1999
10097141 Specific association of the gene product of PKD2 with the TRPC1 channel. External Tsiokas, L., Arnould, T., Zhu, C., Kim, E., Walz, G., Sukhatme, V. P. Proc Natl Acad Sci U S A 1999
9215637 Coassembly of TRP and TRPL produces a distinct store-operated conductance. External Xu, X. Z., Li, H. S., Guggino, W. B., Montell, C. Cell 1997
9192675 Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2. External Tsiokas, L., Kim, E., Arnould, T., Sukhatme, V. P., Walz, G. Proc Natl Acad Sci U S A 1997
9171830 PKD1 interacts with PKD2 through a probable coiled-coil domain. External Qian, F., Germino, F. J., Cai, Y., Zhang, X., Somlo, S., Germino, G. G. Nat Genet 1997
TRP / Interactor

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