TRIP Database - Curated Publications

PMID	Title	Authors	Journal	Year
25295536	TRPM2 mediates ischemic kidney injury and oxidant stress through RAC1.	Gao, G., Wang, W., Tadagavadi, R. K., Briley, N. E., Love, M. I., Miller, B. A., Reeves, W. B.	J Clin Invest	2014
25231975	Casein kinase-mediated phosphorylation of serine 839 is necessary for basolateral localization of the Ca(2)(+)-activated non-selective cation channel TRPM4.	Cerda, O., Caceres, M., Park, K. S., Leiva-Salcedo, E., Romero, A., Varela, D., Trimmer, J. S., Stutzin, A.	Pflugers Arch	2015
25172921	TRPV6 calcium channel translocates to the plasma membrane via Orai1-mediated mechanism and controls cancer cell survival.	Raphael, M., Lehen'kyi, V., Vandenberghe, M., Beck, B., Khalimonchyk, S., Vanden Abeele, F., Farsetti, L., Germain, E., Bokhobza, A., Mihalache, A., Gosset, P., Romanin, C., Clezardin, P., Skryma, R., Prevarskaya, N.	Proc Natl Acad Sci U S A	2014
25139746	Nitric oxide and protein kinase G act on TRPC1 to inhibit 11,12-EET-induced vascular relaxation.	Zhang, P., Ma, Y., Wang, Y., Ma, X., Huang, Y., Li, R. A., Wan, S., Yao, X.	Cardiovasc Res	2014
25130899	Cellular Zinc Levels Are Modulated by TRPML1-TMEM163 Interaction.	Cuajungco, M. P., Basilio, L. C., Silva, J., Hart, T., Tringali, J., Chen, C. C., Biel, M., Grimm, C.	Traffic	2014
25123313	Unique interweaved microtubule scaffold mediates osmosensory transduction via physical interaction with TRPV1.	Prager-Khoutorsky, M., Khoutorsky, A., Bourque, C. W.	Neuron	2014
25114176	TRPV4, TRPC1, and TRPP2 assemble to form a flow-sensitive heteromeric channel.	Du, J., Ma, X., Shen, B., Huang, Y., Birnbaumer, L., Yao, X.	FASEB J	2014
25049082	The phosphatidylinositol(4,5)bisphosphate-binding sequence of transient receptor potential channel canonical 4alpha is critical for its contribution to cardiomyocyte hypertrophy.	Cooley, N., Grubb, D. R., Luo, J., Woodcock, E. A.	Mol Pharmacol	2014
25047048	Depletion of 14-3-3gamma reduces the surface expression of Transient Receptor Potential Melastatin 4b (TRPM4b) Channels and attenuates TRPM4b-mediated glutamate-induced neuronal cell death.	Cho, C. H., Kim, E., Lee, Y. S., Yarishkin, O., Yoo, J. C., Park, J. Y., Hong, S. G., Hwang, E. M.	Mol Brain	2014
25014183	Functional and biochemical interaction between PPARalpha receptors and TRPV1 channels: Potential role in PPARalpha agonists-mediated analgesia.	Ambrosino, P., Soldovieri, M. V., De Maria, M., Russo, C., Taglialatela, M.	Pharmacol Res	2014
25013939	Helminth induced suppression of macrophage activation is correlated with inhibition of calcium channel activity.	Chauhan, A., Sun, Y., Pani, B., Quenumzangbe, F., Sharma, J., Singh, B. B., Mishra, B. B.	PLoS One	2014
25005230	AKAP150-dependent cooperative TRPV4 channel gating is central to endothelium-dependent vasodilation and is disrupted in hypertension.	Sonkusare, S. K., Dalsgaard, T., Bonev, A. D., Hill-Eubanks, D. C., Kotlikoff, M. I., Scott, J. D., Santana, L. F., Nelson, M. T.	Sci Signal	2014
24939696	Following OGD/R, annexin 1 nuclear translocation and subsequent induction of apoptosis in neurons are assisted by myosin IIA in a TRPM7 kinase-dependent manner.	Zhao, Y., Wang, J., Jiang, H., Yu, Z., Li, X., Shi, J.	Mol Neurobiol	2015
24920628	The basal thermal sensitivity of the TRPV1 ion channel is determined by PKCbetaII.	Li, L., Hasan, R., Zhang, X.	J Neurosci	2014
24890824	Transient receptor potential vanilloid 1 activation by dietary capsaicin promotes urinary sodium excretion by inhibiting epithelial sodium channel alpha subunit-mediated sodium reabsorption.	Li, L., Wang, F., Wei, X., Liang, Y., Cui, Y., Gao, F., Zhong, J., Pu, Y., Zhao, Y., Yan, Z., Arendshorst, W. J., Nilius, B., Chen, J., Liu, D., Zhu, Z.	Hypertension	2014
24778429	Local control of TRPV4 channels by AKAP150-targeted PKC in arterial smooth muscle.	Mercado, J., Baylie, R., Navedo, M. F., Yuan, C., Scott, J. D., Nelson, M. T., Brayden, J. E., Santana, L. F.	J Gen Physiol	2014
24740790	Phosphodiesterase 5 inhibition ameliorates angiontensin II-induced podocyte dysmotility via the protein kinase G-mediated downregulation of TRPC6 activity.	Hall, G., Rowell, J., Farinelli, F., Gbadegesin, R. A., Lavin, P., Wu, G., Homstad, A., Malone, A., Lindsey, T., Jiang, R., Spurney, R., Tomaselli, G. F., Kass, D. A., Winn, M. P.	Am J Physiol Renal Physiol	2014
24704446	Reciprocal positive regulation between TRPV6 and NUMB in PTEN-deficient prostate cancer cells.	Kim, S. Y., Hong, C., Wie, J., Kim, E., Kim, B. J., Ha, K., Cho, N. H., Kim, I. G., Jeon, J. H., So, I.	Biochem Biophys Res Commun	2014
24695785	Activation of mu opioid receptors sensitizes transient receptor potential vanilloid type 1 (TRPV1) via beta-arrestin-2-mediated cross-talk.	Rowan, M. P., Bierbower, S. M., Eskander, M. A., Szteyn, K., Por, E. D., Gomez, R., Veldhuis, N., Bunnett, N. W., Jeske, N. A.	PLoS One	2014
24630989	Caspase-11 controls interleukin-1beta release through degradation of TRPC1.	Py, B. F., Jin, M., Desai, B. N., Penumaka, A., Zhu, H., Kober, M., Dietrich, A., Lipinski, M. M., Henry, T., Clapham, D. E., Yuan, J.	Cell Rep	2014
24613381	Heteromeric TRPC3 with TRPC1 formed via its ankyrin repeats regulates the resting cytosolic Ca2+ levels in skeletal muscle.	Woo, J. S., Lee, K. J., Huang, M., Cho, C. H., Lee, E. H.	Biochem Biophys Res Commun	2014
24596097	A disease-causing mutation illuminates the protein membrane topology of the kidney-expressed prohibitin homology (PHB) domain protein podocin.	Schurek, E. M., Volker, L. A., Tax, J., Lamkemeyer, T., Rinschen, M. M., Ungrue, D., Kratz, J. E. 3rd, Sirianant, L., Kunzelmann, K., Chalfie, M., Schermer, B., Benzing, T., Hohne, M.	J Biol Chem	2014
24563462	Trans-activation response (TAR) RNA-binding protein 2 is a novel modulator of transient receptor potential canonical 4 (TRPC4) protein.	Zimmermann, J., Latta, L., Beck, A., Leidinger, P., Fecher-Trost, C., Schlenstedt, G., Meese, E., Wissenbach, U., Flockerzi, V.	J Biol Chem	2014
24509911	Modulation of water efflux through functional interaction between TRPV4 and TMEM16A/anoctamin 1.	Takayama, Y., Shibasaki, K., Suzuki, Y., Yamanaka, A., Tominaga, M.	FASEB J	2014
24464579	Molecular determinants mediating gating of Transient Receptor Potential Canonical (TRPC) channels by stromal interaction molecule 1 (STIM1).	Lee, K. P., Choi, S., Hong, J. H., Ahuja, M., Graham, S., Ma, R., So, I., Shin, D. M., Muallem, S., Yuan, J. P.	J Biol Chem	2014
24459142	Polycystin-1 negatively regulates Polycystin-2 expression via the aggresome/autophagosome pathway.	Cebotaru, V., Cebotaru, L., Kim, H., Chiaravalli, M., Boletta, A., Qian, F., Guggino, W. B.	J Biol Chem	2014
24391909	Role of endogenous ENaC and TRP channels in the myogenic response of rat posterior cerebral arteries.	Kim, E. C., Choi, S. K., Lim, M., Yeon, S. I., Lee, Y. H.	PLoS One	2013
24385424	The TRPM6 kinase domain determines the Mg.ATP sensitivity of TRPM7/M6 heteromeric ion channels.	Zhang, Z., Yu, H., Huang, J., Faouzi, M., Schmitz, C., Penner, R., Fleig, A.	J Biol Chem	2014
24337049	Cooperative interaction of trp melastatin channel transient receptor potential (TRPM2) with its splice variant TRPM2 short variant is essential for endothelial cell apoptosis.	Hecquet, C. M., Zhang, M., Mittal, M., Vogel, S. M., Di, A., Gao, X., Bonini, M. G., Malik, A. B.	Circ Res	2014
24269818	The Ca2+ channel TRPML3 specifically interacts with the mammalian ATG8 homologue GATE16 to regulate autophagy.	Choi, S., Kim, H. J.	Biochem Biophys Res Commun	2014
24269608	The TRPM8 channel forms a complex with the 5-HT1B receptor and phospholipase D that amplifies its reversal of pain hypersensitivity.	Vinuela-Fernandez, I., Sun, L., Jerina, H., Curtis, J., Allchorne, A., Gooding, H., Rosie, R., Holland, P., Tas, B., Mitchell, R., Fleetwood-Walker, S.	Neuropharmacology	2014
24157948	Piezo1-dependent stretch-activated channels are inhibited by Polycystin-2 in renal tubular epithelial cells.	Peyronnet, R., Martins, J. R., Duprat, F., Demolombe, S., Arhatte, M., Jodar, M., Tauc, M., Duranton, C., Paulais, M., Teulon, J., Honore, E., Patel, A.	EMBO Rep	2013
24147119	TRPV1 channels are functionally coupled with BK(mSlo1) channels in rat dorsal root ganglion (DRG) neurons.	Wu, Y., Liu, Y., Hou, P., Yan, Z., Kong, W., Liu, B., Li, X., Yao, J., Zhang, Y., Qin, F., Ding, J.	PLoS One	2013
24146259	Expression and localization of TRPC proteins in rat ventricular myocytes at various developmental stages.	Jiang, Y., Huang, H., Liu, P., Wei, H., Zhao, H., Feng, Y., Wang, W., Niu, W.	Cell Tissue Res	2014
24114537	Orphan receptor GPR179 forms macromolecular complexes with components of metabotropic signaling cascade in retina ON-bipolar neurons.	Orlandi, C., Cao, Y., Martemyanov, K. A.	Invest Ophthalmol Vis Sci	2013
24114458	Inhibition of the Sur1-Trpm4 channel reduces neuroinflammation and cognitive impairment in subarachnoid hemorrhage.	Tosun, C., Kurland, D. B., Mehta, R., Castellani, R. J., deJong, J. L., Kwon, M. S., Woo, S. K., Gerzanich, V., Simard, J. M.	Stroke	2013
24036102	Identification of voltage-gated K(+) channel beta 2 (Kvbeta2) subunit as a novel interaction partner of the pain transducer Transient Receptor Potential Vanilloid 1 channel (TRPV1).	Bavassano, C., Marvaldi, L., Langeslag, M., Sarg, B., Lindner, H., Klimaschewski, L., Kress, M., Ferrer-Montiel, A., Knaus, H. G.	Biochim Biophys Acta	2013
24022404	Myristoylated alanine-rich C kinase substrate coordinates native TRPC1 channel activation by phosphatidylinositol 4,5-bisphosphate and protein kinase C in vascular smooth muscle.	Shi, J., Birnbaumer, L., Large, W. A., Albert, A. P.	FASEB J	2014
24011658	Activation of TRPC4beta by Galphai subunit increases Ca2+ selectivity and controls neurite morphogenesis in cultured hippocampal neuron.	Jeon, J. P., Roh, S. E., Wie, J., Kim, J., Kim, H., Lee, K. P., Yang, D., Jeon, J. H., Cho, N. H., Kim, I. G., Kang, D. E., Kim, H. J., So, I.	Cell Calcium	2013
23994313	Transient receptor potential ankyrin-1 (TRPA1) modulates store-operated Ca(2+) entry by regulation of STIM1-Orai1 association.	Albarran, L., Lopez, J. J., Dionisio, N., Smani, T., Salido, G. M., Rosado, J. A.	Biochim Biophys Acta	2013
23977387	TRPP2 and TRPV4 form an EGF-activated calcium permeable channel at the apical membrane of renal collecting duct cells.	Zhang, Z. R., Chu, W. F., Song, B., Gooz, M., Zhang, J. N., Yu, C. J., Jiang, S., Baldys, A., Gooz, P., Steele, S., Owsianik, G., Nilius, B., Komlosi, P., Bell, P. D.	PLoS One	2013
23911290	Opiates modulate thermosensation by internalizing cold receptor TRPM8.	Shapovalov, G., Gkika, D., Devilliers, M., Kondratskyi, A., Gordienko, D., Busserolles, J., Bokhobza, A., Eschalier, A., Skryma, R., Prevarskaya, N.	Cell Rep	2013
23770672	A TRPC1 protein-dependent pathway regulates osteoclast formation and function.	Ong, E. C., Nesin, V., Long, C. L., Bai, C. X., Guz, J. L., Ivanov, I. P., Abramowitz, J., Birnbaumer, L., Humphrey, M. B., Tsiokas, L.	J Biol Chem	2013
23747339	Post-translational loss of renal TRPV5 calcium channel expression, Ca(2+) wasting, and bone loss in experimental colitis.	Radhakrishnan, V. M., Ramalingam, R., Larmonier, C. B., Thurston, R. D., Laubitz, D., Midura-Kiela, M. T., McFadden, R. M., Kuro-O, M., Kiela, P. R., Ghishan, F. K.	Gastroenterology	2013
23699529	Mapping the binding site of TRPV1 on AKAP79: implications for inflammatory hyperalgesia.	Btesh, J., Fischer, M. J., Stott, K., McNaughton, P. A.	J Neurosci	2013
23690576	Phosphatidylinositol-4,5-biphosphate-dependent rearrangement of TRPV4 cytosolic tails enables channel activation by physiological stimuli.	Garcia-Elias, A., Mrkonjic, S., Pardo-Pastor, C., Inada, H., Hellmich, U. A., Rubio-Moscardo, F., Plata, C., Gaudet, R., Vicente, R., Valverde, M. A.	Proc Natl Acad Sci U S A	2013
23686296	Functional transient receptor potential canonical type 1 channels in human atrial myocytes.	Zhang, Y. H., Wu, H. J., Che, H., Sun, H. Y., Cheng, L. C., Li, X., Au, W. K., Tse, H. F., Li, G. R.	Pflugers Arch	2013
23671622	Characterization of the S100A1 protein binding site on TRPC6 C-terminus.	Bily, J., Grycova, L., Holendova, B., Jirku, M., Janouskova, H., Bousova, K., Teisinger, J.	PLoS One	2013
23645677	Gain-of-function mutations in transient receptor potential C6 (TRPC6) activate extracellular signal-regulated kinases 1/2 (ERK1/2).	Chiluiza, D., Krishna, S., Schumacher, V. A., Schlondorff, J.	J Biol Chem	2013
23616546	Disrupting sensitization of transient receptor potential vanilloid subtype 1 inhibits inflammatory hyperalgesia.	Fischer, M. J., Btesh, J., McNaughton, P. A.	J Neurosci	2013
23508958	Excitation and modulation of TRPA1, TRPV1, and TRPM8 channel-expressing sensory neurons by the pruritogen chloroquine.	Than, J. Y., Li, L., Hasan, R., Zhang, X.	J Biol Chem	2013
23469151	A novel ion channel formed by interaction of TRPML3 with TRPV5.	Guo, Z., Grimm, C., Becker, L., Ricci, A. J., Heller, S.	PLoS One	2013
23418601	Systematic screens for proteins that interact with the mucolipidosis type IV protein TRPML1.	Spooner, E., McLaughlin, B. M., Lepow, T., Durns, T. A., Randall, J., Upchurch, C., Miller, K., Campbell, E. M., Fares, H.	PLoS One	2013
23395841	The polybasic lysine-rich domain of plasma membrane-resident STIM1 is essential for the modulation of store-operated divalent cation entry by extracellular calcium.	Jardin, I., Dionisio, N., Frischauf, I., Berna-Erro, A., Woodard, G. E., Lopez, J. J., Salido, G. M., Rosado, J. A.	Cell Signal	2013
23390129	Hyperphosphorylation of polycystin-2 at a critical residue in disease reveals an essential role for polycystin-1-regulated dephosphorylation.	Streets, A. J., Wessely, O., Peters, D. J., Ong, A. C.	Hum Mol Genet	2013
23375350	Regulation of store-operated calcium entry by FK506-binding immunophilins.	Kadeba, P. I., Vasauskas, A. A., Chen, H., Wu, S., Scammell, J. G., Cioffi, D. L.	Cell Calcium	2013
23360390	Phosphorylation regulates TRPV1 association with beta-arrestin-2.	Por, E. D., Gomez, R., Akopian, A. N., Jeske, N. A.	Biochem J	2013
23345400	Occludin is required for TRPV1-modulated paracellular permeability in the submandibular gland.	Cong, X., Zhang, Y., Yang, N. Y., Li, J., Ding, C., Ding, Q. W., Su, Y. C., Mei, M., Guo, X. H., Wu, L. L., Yu, G. Y.	J Cell Sci	2013
23264624	Scaffolding by A-kinase anchoring protein enhances functional coupling between adenylyl cyclase and TRPV1 channel.	Efendiev, R., Bavencoffe, A., Hu, H., Zhu, M. X., Dessauer, C. W.	J Biol Chem	2013
23255597	The sulfonylurea receptor 1 (Sur1)-transient receptor potential melastatin 4 (Trpm4) channel.	Woo, S. K., Kwon, M. S., Ivanov, A., Gerzanich, V., Simard, J. M.	J Biol Chem	2013
23228564	FKBP52 is involved in the regulation of SOCE channels in the human platelets and MEG 01 cells.	Lopez, E., Berna-Erro, A., Salido, G. M., Rosado, J. A., Redondo, P. C.	Biochim Biophys Acta	2013
23212381	Molecular mechanism of the assembly of an acid-sensing receptor ion channel complex.	Yu, Y., Ulbrich, M. H., Li, M. H., Dobbins, S., Zhang, W. K., Tong, L., Isacoff, E. Y., Yang, J.	Nat Commun	2012
23171048	SNF8, a member of the ESCRT-II complex, interacts with TRPC6 and enhances its channel activity.	Carrasquillo, R., Tian, D., Krishna, S., Pollak, M. R., Greka, A., Schlondorff, J.	BMC Cell Biol	2012
23159249	Recurrent de novo mutations in PACS1 cause defective cranial-neural-crest migration and define a recognizable intellectual-disability syndrome.	Schuurs-Hoeijmakers, J. H., Oh, E. C., Vissers, L. E., Swinkels, M. E., Gilissen, C., Willemsen, M. A., Holvoet, M., Steehouwer, M., Veltman, J. A., de Vries, B. B., van Bokhoven, H., de Brouwer, A. P., Katsanis, N., Devriendt, K., Brunner, H. G.	Am J Hum Genet	2012
23142606	Cannabinoid receptor 1 suppresses transient receptor potential vanilloid 1-induced inflammatory responses to corneal injury.	Yang, Y., Yang, H., Wang, Z., Varadaraj, K., Kumari, S. S., Mergler, S., Okada, Y., Saika, S., Kingsley, P. J., Marnett, L. J., Reinach, P. S.	Cell Signal	2013
23140583	Regulation of calcium influx and signaling pathway in cancer cells via TRPV6-Numb1 interaction.	Kim, S. Y., Yang, D., Myeong, J., Ha, K., Kim, S. H., Park, E. J., Kim, I. G., Cho, N. H., Lee, K. P., Jeon, J. H., So, I.	Cell Calcium	2013
23119017	Integrative binding sites within intracellular termini of TRPV1 receptor.	Grycova, L., Holendova, B., Bumba, L., Bily, J., Jirku, M., Lansky, Z., Teisinger, J.	PLoS One	2012
23109716	Distinct properties of Ca2+-calmodulin binding to N- and C-terminal regulatory regions of the TRPV1 channel.	Lau, S. Y., Procko, E., Gaudet, R.	J Gen Physiol	2012
23077056	Cyclin-dependent kinase 5 controls TRPV1 membrane trafficking and the heat sensitivity of nociceptors through KIF13B.	Xing, B. M., Yang, Y. R., Du, J. X., Chen, H. J., Qi, C., Huang, Z. H., Zhang, Y., Wang, Y.	J Neurosci	2012
23068106	Different binding property of STIM1 and its novel splice variant STIM1L to Orai1, TRPC3, and TRPC6 channels.	Horinouchi, T., Higashi, T., Higa, T., Terada, K., Mai, Y., Aoyagi, H., Hatate, C., Nepal, P., Horiguchi, M., Harada, T., Miwa, S.	Biochem Biophys Res Commun	2012
23045459	An elevation in physical coupling of type 1 inositol 1,4,5-trisphosphate (IP3) receptors to transient receptor potential 3 (TRPC3) channels constricts mesenteric arteries in genetic hypertension.	Adebiyi, A., Thomas-Gatewood, C. M., Leo, M. D., Kidd, M. W., Neeb, Z. P., Jaggar, J. H.	Hypertension	2012
23034388	TRPC1 and Orai1 interact with STIM1 and mediate capacitative Ca(2+) entry caused by acute hypoxia in mouse pulmonary arterial smooth muscle cells.	Ng, L. C., O'Neill, K. G., French, D., Airey, J. A., Singer, C. A., Tian, H., Shen, X. M., Hume, J. R.	Am J Physiol Cell Physiol	2012
22952227	beta-Arrestin-2 desensitizes the transient receptor potential vanilloid 1 (TRPV1) channel.	Por, E. D., Bierbower, S. M., Berg, K. A., Gomez, R., Akopian, A. N., Wetsel, W. C., Jeske, N. A.	J Biol Chem	2012
22932896	Canonical transient receptor potential (TRPC) 1 acts as a negative regulator for vanilloid TRPV6-mediated Ca2+ influx.	Schindl, R., Fritsch, R., Jardin, I., Frischauf, I., Kahr, H., Muik, M., Riedl, M. C., Groschner, K., Romanin, C.	J Biol Chem	2012
22789851	Activation of NMDA receptors leads to phosphorylation of TRPV1 S800 by protein kinase C and A-Kinase anchoring protein 150 in rat trigeminal ganglia.	Lee, J., Chung, M. K., Ro, J. Y.	Biochem Biophys Res Commun	2012
22778254	Extracellular Ca(2+) sensing in salivary ductal cells.	Bandyopadhyay, B. C., Swaim, W. D., Sarkar, A., Liu, X., Ambudkar, I. S.	J Biol Chem	2012
22759789	Identification of Ser/Thr phosphorylation sites in the C2-domain of phospholipase C gamma2 (PLCgamma2) using TRPM7-kinase.	Deason-Towne, F., Perraud, A. L., Schmitz, C.	Cell Signal	2012
22750945	Direct inhibition of the cold-activated TRPM8 ion channel by Galphaq.	Zhang, X., Mak, S., Li, L., Parra, A., Denlinger, B., Belmonte, C., McNaughton, P. A.	Nat Cell Biol	2012
22640869	Capacitative and non-capacitative signaling complexes in human platelets.	Berna-Erro, A., Galan, C., Dionisio, N., Gomez, L. J., Salido, G. M., Rosado, J. A.	Biochim Biophys Acta	2012
22609428	Functional interactions between NMDA receptors and TRPV1 in trigeminal sensory neurons mediate mechanical hyperalgesia in the rat masseter muscle.	Lee, J., Saloman, J. L., Weiland, G., Auh, Q. S., Chung, M. K., Ro, J. Y.	Pain	2012
22592407	Polyamines regulate intestinal epithelial restitution through TRPC1-mediated Ca(2)+ signaling by differentially modulating STIM1 and STIM2.	Rao, J. N., Rathor, N., Zhuang, R., Zou, T., Liu, L., Xiao, L., Turner, D. J., Wang, J. Y.	Am J Physiol Cell Physiol	2012
22534489	Orai1 determines calcium selectivity of an endogenous TRPC heterotetramer channel.	Cioffi, D. L., Wu, S., Chen, H., Alexeyev, M., St Croix, C. M., Pitt, B. R., Uhlig, S., Stevens, T.	Circ Res	2012
22518003	Protein kinase G inhibits flow-induced Ca2+ entry into collecting duct cells.	Du, J., Wong, W. Y., Sun, L., Huang, Y., Yao, X.	J Am Soc Nephrol	2012
22506990	Homers regulate calcium entry and aggregation in human platelets: a role for Homers in the association between STIM1 and Orai1.	Jardin, I., Albarran, L., Bermejo, N., Salido, G. M., Rosado, J. A.	Biochem J	2012
22492541	Calcium/calmodulin-signaling supports TRPV4 activation in osteoclasts and regulates bone mass.	Masuyama, R., Mizuno, A., Komori, H., Kajiya, H., Uekawa, A., Kitaura, H., Okabe, K., Ohyama, K., Komori, T.	J Bone Miner Res	2012
22460725	The TRPM8 ion channel comprises direct Gq protein-activating capacity.	Klasen, K., Hollatz, D., Zielke, S., Gisselmann, G., Hatt, H., Wetzel, C. H.	Pflugers Arch	2012
22457348	Selective Galphai subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels.	Jeon, J. P., Hong, C., Park, E. J., Jeon, J. H., Cho, N. H., Kim, I. G., Choe, H., Muallem, S., Kim, H. J., So, I.	J Biol Chem	2012
22451679	Transforming growth factor-beta1 regulates Cdk5 activity in primary sensory neurons.	Utreras, E., Keller, J., Terse, A., Prochazkova, M., Iadarola, M. J., Kulkarni, A. B.	J Biol Chem	2012
22451665	Calmodulin and S100A1 protein interact with N terminus of TRPM3 channel.	Holakovska, B., Grycova, L., Jirku, M., Sulc, M., Bumba, L., Teisinger, J.	J Biol Chem	2012
22451268	Implication of AMP-activated protein kinase in transient receptor potential vanilloid type 1-mediated activation of endothelial nitric oxide synthase.	Ching, L. C., Chen, C. Y., Su, K. H., Hou, H. H., Shyue, S. K., Kou, Y. R., Lee, T. S.	Mol Med	2012
22446186	Neurotoxin-induced ER stress in mouse dopaminergic neurons involves downregulation of TRPC1 and inhibition of AKT/mTOR signaling.	Selvaraj, S., Sun, Y., Watt, J. A., Wang, S., Lei, S., Birnbaumer, L., Singh, B. B.	J Clin Invest	2012
22374181	Importance of transient receptor potential vanilloid 4 (TRPV4) in epidermal barrier function in human skin keratinocytes.	Kida, N., Sokabe, T., Kashio, M., Haruna, K., Mizuno, Y., Suga, Y., Nishikawa, K., Kanamaru, A., Hongo, M., Oba, A., Tominaga, M.	Pflugers Arch	2012
22309793	Interaction of transient receptor potential vanilloid 4 with annexin A2 and tubulin beta 5.	Huai, J., Zhang, Y., Liu, Q. M., Ge, H. Y., Arendt-Nielsen, L., Jiang, H., Yue, S. W.	Neurosci Lett	2012
22262838	Intact microtubules preserve transient receptor potential vanilloid 1 (TRPV1) functionality through receptor binding.	Storti, B., Bizzarri, R., Cardarelli, F., Beltram, F.	J Biol Chem	2012
22226147	The juvenile myoclonic epilepsy-related protein EFHC1 interacts with the redox-sensitive TRPM2 channel linked to cell death.	Katano, M., Numata, T., Aguan, K., Hara, Y., Kiyonaka, S., Yamamoto, S., Miki, T., Sawamura, S., Suzuki, T., Yamakawa, K., Mori, Y.	Cell Calcium	2012
22210847	The Ca(2+) sensor stromal interaction molecule 1 (STIM1) is necessary and sufficient for the store-operated Ca(2+) entry function of transient receptor potential canonical (TRPC) 1 and 4 channels in endothelial cells.	Sundivakkam, P. C., Freichel, M., Singh, V., Yuan, J. P., Vogel, S. M., Flockerzi, V., Malik, A. B., Tiruppathi, C.	Mol Pharmacol	2012
22201561	Opposite regulatory effects of TRPC1 and TRPC5 on neurite outgrowth in PC12 cells.	Heo, D. K., Chung, W. Y., Park, H. W., Yuan, J. P., Lee, M. G., Kim, J. Y.	Cell Signal	2012
22180838	Phosphatidylinositol 4,5-bisphosphate (PIP(2)) controls magnesium gatekeeper TRPM6 activity.	Xie, J., Sun, B., Du, J., Yang, W., Chen, H. C., Overton, J. D., Runnels, L. W., Yue, L.	Sci Rep	2011
22174419	Receptor for activated C kinase 1 (RACK1) inhibits function of transient receptor potential (TRP)-type channel Pkd2L1 through physical interaction.	Yang, J., Wang, Q., Zheng, W., Tuli, J., Li, Q., Wu, Y., Hussein, S., Dai, X. Q., Shafiei, S., Li, X. G., Shen, P. Y., Tu, J. C., Chen, X. Z.	J Biol Chem	2012
22155451	The proteoglycan syndecan 4 regulates transient receptor potential canonical 6 channels via RhoA/Rho-associated protein kinase signaling.	Liu, Y., Echtermeyer, F., Thilo, F., Theilmeier, G., Schmidt, A., Schulein, R., Jensen, B. L., Loddenkemper, C., Jankowski, V., Marcussen, N., Gollasch, M., Arendshorst, W. J., Tepel, M.	Arterioscler Thromb Vasc Biol	2012
22144671	Heteromeric canonical transient receptor potential 1 and 4 channels play a critical role in epileptiform burst firing and seizure-induced neurodegeneration.	Phelan, K. D., Mock, M. M., Kretz, O., Shwe, U. T., Kozhemyakin, M., Greenfield, L. J., Dietrich, A., Birnbaumer, L., Freichel, M., Flockerzi, V., Zheng, F.	Mol Pharmacol	2012
22135323	A TRPC5-regulated calcium signaling pathway controls dendrite patterning in the mammalian brain.	Puram, S. V., Riccio, A., Koirala, S., Ikeuchi, Y., Kim, A. H., Corfas, G., Bonni, A.	Genes Dev	2011
22101010	Phosphorylation on the Ser 824 residue of TRPV4 prefers to bind with F-actin than with microtubules to expand the cell surface area.	Shin, S. H., Lee, E. J., Hyun, S., Chun, J., Kim, Y., Kang, S. S.	Cell Signal	2012
22088247	[Impact of stromal interaction molecule 1 silencing on cell cycle of endothelial progenitor cells].	Kuang, C. Y., Huang, L., Yu, Y., Deng, M. Y., Wang, K., Qian, D. H.	Zhonghua Xin Xue Guan Bing Za Zhi	2011
22027011	A cardiac pathway of cyclic GMP-independent signaling of guanylyl cyclase A, the receptor for atrial natriuretic peptide.	Klaiber, M., Dankworth, B., Kruse, M., Hartmann, M., Nikolaev, V. O., Yang, R. B., Volker, K., Gassner, B., Oberwinkler, H., Feil, R., Freichel, M., Groschner, K., Skryabin, B. V., Frantz, S., Birnbaumer, L., Pongs, O., Kuhn, M.	Proc Natl Acad Sci U S A	2011
22001259	Adenylate cyclase/cAMP/protein kinase A signaling pathway inhibits endothelin type A receptor-operated Ca(2)(+) entry mediated via transient receptor potential canonical 6 channels.	Horinouchi, T., Higa, T., Aoyagi, H., Nishiya, T., Terada, K., Miwa, S.	J Pharmacol Exp Ther	2012
21996795	Expression and association of TRPC1 with TRPC3 during skeletal myogenesis.	Cheung, K. K., Yeung, S. S., Au, S. W., Lam, L. S., Dai, Z. Q., Li, Y. H., Yeung, E. W.	Muscle Nerve	2011
21968068	TRPC1 proteins confer PKC and phosphoinositol activation on native heteromeric TRPC1/C5 channels in vascular smooth muscle: comparative study of wild-type and TRPC1-/- mice.	Shi, J., Ju, M., Abramowitz, J., Large, W. A., Birnbaumer, L., Albert, A. P.	FASEB J	2012
21952826	Tissue transglutaminase inhibits the TRPV5-dependent calcium transport in an N-glycosylation-dependent manner.	Boros, S., Xi, Q., Dimke, H., van der Kemp, A. W., Tudpor, K., Verkaart, S., Lee, K. P., Bindels, R. J., Hoenderop, J. G.	Cell Mol Life Sci	2012
21906983	Systematic and quantitative assessment of the ubiquitin-modified proteome.	Kim, W., Bennett, E. J., Huttlin, E. L., Guo, A., Li, J., Possemato, A., Sowa, M. E., Rad, R., Rush, J., Comb, M. J., Harper, J. W., Gygi, S. P.	Mol Cell	2011
21890473	A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.	Wagner, S. A., Beli, P., Weinert, B. T., Nielsen, M. L., Cox, J., Mann, M., Choudhary, C.	Mol Cell Proteomics	2011
21871867	Electrophysiological properties of heteromeric TRPV4-C1 channels.	Ma, X., Nilius, B., Wong, J. W., Huang, Y., Yao, X.	Biochim Biophys Acta	2011
21844219	Coexpression and activation of TRPV1 suppress the activity of the KCNQ2/3 channel.	Zhang, X. F., Han, P., Neelands, T. R., McGaraughty, S., Honore, P., Surowy, C. S., Zhang, D.	J Gen Physiol	2011
21837266	Mutation of a putative S-nitrosylation site of TRPV4 protein facilitates the channel activates.	Lee, E. J., Shin, S. H., Hyun, S., Chun, J., Kang, S. S.	Animal Cells Syst (Seoul)	2011
21832182	TRPM1 forms complexes with nyctalopin in vivo and accumulates in postsynaptic compartment of ON-bipolar neurons in mGluR6-dependent manner.	Cao, Y., Posokhova, E., Martemyanov, K. A.	J Neurosci	2011
21799177	Cilostazol suppresses angiotensin II-induced vasoconstriction via protein kinase A-mediated phosphorylation of the transient receptor potential canonical 6 channel.	Nishioka, K., Nishida, M., Ariyoshi, M., Jian, Z., Saiki, S., Hirano, M., Nakaya, M., Sato, Y., Kita, S., Iwamoto, T., Hirano, K., Inoue, R., Kurose, H.	Arterioscler Thromb Vasc Biol	2011
21757714	The transient receptor potential (TRP) channel TRPC3 TRP domain and AMP-activated protein kinase binding site are required for TRPC3 activation by erythropoietin.	Hirschler-Laszkiewicz, I., Tong, Q., Waybill, K., Conrad, K., Keefer, K., Zhang, W., Chen, S. J., Cheung, J. Y., Miller, B. A.	J Biol Chem	2011
21734298	A role for nyctalopin, a small leucine-rich repeat protein, in localizing the TRP melastatin 1 channel to retinal depolarizing bipolar cell dendrites.	Pearring, J. N., Bojang, P. Jr, Shen, Y., Koike, C., Furukawa, T., Nawy, S., Gregg, R. G.	J Neurosci	2011
21672930	A key role of TRPC channels in the regulation of electromechanical activity of the developing heart.	Sabourin, J., Robin, E., Raddatz, E.	Cardiovasc Res	2011
21670282	Serine-threonine kinase with-no-lysine 4 (WNK4) controls blood pressure via transient receptor potential canonical 3 (TRPC3) in the vasculature.	Park, H. W., Kim, J. Y., Choi, S. K., Lee, Y. H., Zeng, W., Kim, K. H., Muallem, S., Lee, M. G.	Proc Natl Acad Sci U S A	2011
21576356	Molecular mechanisms of calmodulin action on TRPV5 and modulation by parathyroid hormone.	de Groot, T., Kovalevskaya, N. V., Verkaart, S., Schilderink, N., Felici, M., van der Hagen, E. A., Bindels, R. J., Vuister, G. W., Hoenderop, J. G.	Mol Cell Biol	2011
21540176	Transient receptor potential mucolipin 1 (TRPML1) and two-pore channels are functionally independent organellar ion channels.	Yamaguchi, S., Jha, A., Li, Q., Soyombo, A. A., Dickinson, G. D., Churamani, D., Brailoiu, E., Patel, S., Muallem, S.	J Biol Chem	2011
21493704	Molecular mechanisms of activation of endothelial nitric oxide synthase mediated by transient receptor potential vanilloid type 1.	Ching, L. C., Kou, Y. R., Shyue, S. K., Su, K. H., Wei, J., Cheng, L. C., Yu, Y. B., Pan, C. C., Lee, T. S.	Cardiovasc Res	2011
21402151	Functional regulation of transient receptor potential canonical 7 by cGMP-dependent protein kinase Ialpha.	Yuasa, K., Matsuda, T., Tsuji, A.	Cell Signal	2011
21307093	Pkd1l1 establishes left-right asymmetry and physically interacts with Pkd2.	Field, S., Riley, K. L., Grimes, D. T., Hilton, H., Simon, M., Powles-Glover, N., Siggers, P., Bogani, D., Greenfield, A., Norris, D. P.	Development	2011
21278253	Transient receptor potential melastatin 1 (TRPM1) is an ion-conducting plasma membrane channel inhibited by zinc ions.	Lambert, S., Drews, A., Rizun, O., Wagner, T. F., Lis, A., Mannebach, S., Plant, S., Portz, M., Meissner, M., Philipp, S. E., Oberwinkler, J.	J Biol Chem	2011
21262839	An aquaporin-4/transient receptor potential vanilloid 4 (AQP4/TRPV4) complex is essential for cell-volume control in astrocytes.	Benfenati, V., Caprini, M., Dovizio, M., Mylonakou, M. N., Ferroni, S., Ottersen, O. P., Amiry-Moghaddam, M.	Proc Natl Acad Sci U S A	2011
21224396	LAPTMs regulate lysosomal function and interact with mucolipin 1: new clues for understanding mucolipidosis type IV.	Vergarajauregui, S., Martina, J. A., Puertollano, R.	J Cell Sci	2011
21139048	Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level.	Danielsen, J. M., Sylvestersen, K. B., Bekker-Jensen, S., Szklarczyk, D., Poulsen, J. W., Horn, H., Jensen, L. J., Mailand, N., Nielsen, M. L.	Mol Cell Proteomics	2011
20926660	Ca2+-dependent desensitization of TRPV2 channels is mediated by hydrolysis of phosphatidylinositol 4,5-bisphosphate.	Mercado, J., Gordon-Shaag, A., Zagotta, W. N., Gordon, S. E.	J Neurosci	2010
20811636	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	Giannone, R. J., McDonald, H. W., Hurst, G. B., Shen, R. F., Wang, Y., Liu, Y.	PLoS One	2010
20736310	Heteromultimeric TRPML channel assemblies play a crucial role in the regulation of cell viability models and starvation-induced autophagy.	Zeevi, D. A., Lev, S., Frumkin, A., Minke, B., Bach, G.	J Cell Sci	2010
20729296	The retinitis pigmentosa protein RP2 interacts with polycystin 2 and regulates cilia-mediated vertebrate development.	Hurd, T., Zhou, W., Jenkins, P., Liu, C. J., Swaroop, A., Khanna, H., Martens, J., Hildebrandt, F., Margolis, B.	Hum Mol Genet	2010
20705915	Depletion of intracellular Ca2+ stores stimulates the translocation of vanilloid transient receptor potential 4-c1 heteromeric channels to the plasma membrane.	Ma, X., Cao, J., Luo, J., Nilius, B., Huang, Y., Ambudkar, I. S., Yao, X.	Arterioscler Thromb Vasc Biol	2010
20686800	Characterization of calmodulin binding domains in TRPV2 and TRPV5 C-tails.	Holakovska, B., Grycova, L., Bily, J., Teisinger, J.	Amino Acids	2011
20682256	Atomic force microscopy reveals the alternating subunit arrangement of the TRPP2-TRPV4 heterotetramer.	Stewart, A. P., Smith, G. D., Sandford, R. N., Edwardson, J. M.	Biophys J	2010
20660561	TRPC6 channels stimulated by angiotensin II are inhibited by TRPC1/C5 channel activity through a Ca2+- and PKC-dependent mechanism in native vascular myocytes.	Shi, J., Ju, M., Saleh, S. N., Albert, A. P., Large, W. A.	J Physiol	2010
20650893	Arresting a transient receptor potential (TRP) channel: beta-arrestin 1 mediates ubiquitination and functional down-regulation of TRPV4.	Shukla, A. K., Kim, J., Ahn, S., Xiao, K., Shenoy, S. K., Liedtke, W., Lefkowitz, R. J.	J Biol Chem	2010
20538909	Interaction between PKD1L3 and PKD2L1 through their transmembrane domains is required for localization of PKD2L1 at taste pores in taste cells of circumvallate and foliate papillae.	Ishimaru, Y., Katano, Y., Yamamoto, K., Akiba, M., Misaka, T., Roberts, R. W., Asakura, T., Matsunami, H., Abe, K.	FASEB J	2010
20492691	The TRPC2 channel forms protein-protein interactions with Homer and RTP in the rat vomeronasal organ.	Mast, T. G., Brann, J. H., Fadool, D. A.	BMC Neurosci	2010
20488539	Effect of cell swelling on ER/PM junctional interactions and channel assembly involved in SOCE.	Liu, X., Ong, H. L., Pani, B., Johnson, K., Swaim, W. B., Singh, B., Ambudkar, I.	Cell Calcium	2010
20413591	The TRPV4 channel contributes to intercellular junction formation in keratinocytes.	Sokabe, T., Fukumi-Tominaga, T., Yonemura, S., Mizuno, A., Tominaga, M.	J Biol Chem	2010
20403327	TRP channel regulates EGFR signaling in hair morphogenesis and skin barrier formation.	Cheng, X., Jin, J., Hu, L., Shen, D., Dong, X. P., Samie, M. A., Knoff, J., Eisinger, B., Liu, M. L., Huang, S. M., Caterina, M. J., Dempsey, P., Michael, L. E., Dlugosz, A. A., Andrews, N. C., Clapham, D. E., Xu, H.	Cell	2010
20378853	Isoform-selective physical coupling of TRPC3 channels to IP3 receptors in smooth muscle cells regulates arterial contractility.	Adebiyi, A., Zhao, G., Narayanan, D., Thomas-Gatewood, C. M., Bannister, J. P., Jaggar, J. H.	Circ Res	2010
20375013	Polycystin-2 activation by inositol 1,4,5-trisphosphate-induced Ca2+ release requires its direct association with the inositol 1,4,5-trisphosphate receptor in a signaling microdomain.	Sammels, E., Devogelaere, B., Mekahli, D., Bultynck, G., Missiaen, L., Parys, J. B., Cai, Y., Somlo, S., De Smedt, H.	J Biol Chem	2010
20351294	TRPC channels are necessary mediators of pathologic cardiac hypertrophy.	Wu, X., Eder, P., Chang, B., Molkentin, J. D.	Proc Natl Acad Sci U S A	2010
20346379	Involvement of Rab9 and Rab11 in the intracellular trafficking of TRPC6.	Cayouette, S., Bousquet, S. M., Francoeur, N., Dupre, E., Monet, M., Gagnon, H., Guedri, Y. B., Lavoie, C., Boulay, G.	Biochim Biophys Acta	2010
20231274	Contribution of TRPV1-TRPA1 interaction to the single channel properties of the TRPA1 channel.	Staruschenko, A., Jeske, N. A., Akopian, A. N.	J Biol Chem	2010
20194530	Expression and association of TRPC subtypes with Orai1 and STIM1 in human parathyroid.	Lu, M., Branstrom, R., Berglund, E., Hoog, A., Bjorklund, P., Westin, G., Larsson, C., Farnebo, L. O., Forsberg, L.	J Mol Endocrinol	2010
20179142	GABAA receptor associated protein (GABARAP) modulates TRPV1 expression and channel function and desensitization.	Lainez, S., Valente, P., Ontoria-Oviedo, I., Estevez-Herrera, J., Camprubi-Robles, M., Ferrer-Montiel, A., Planells-Cases, R.	FASEB J	2010
20179100	Ca2+ influx and protein scaffolding via TRPC3 sustain PKCbeta and ERK activation in B cells.	Numaga, T., Nishida, M., Kiyonaka, S., Kato, K., Katano, M., Mori, E., Kurosaki, T., Inoue, R., Hikida, M., Putney, J. W. Jr, Mori, Y.	J Cell Sci	2010
20164195	The phospholipid-binding protein SESTD1 is a novel regulator of the transient receptor potential channels TRPC4 and TRPC5.	Miehe, S., Bieberstein, A., Arnould, I., Ihdene, O., Rutten, H., Strubing, C.	J Biol Chem	2010
20107112	Role of cAMP/PKA signaling cascade in vasopressin-induced trafficking of TRPC3 channels in principal cells of the collecting duct.	Goel, M., Zuo, C. D., Schilling, W. P.	Am J Physiol Renal Physiol	2010
20095964	S165F mutation of junctophilin 2 affects Ca2+ signalling in skeletal muscle.	Woo, J. S., Hwang, J. H., Ko, J. K., Weisleder, N., Kim do, H., Ma, J., Lee, E. H.	Biochem J	2010
20093626	Functional role of vanilloid transient receptor potential 4-canonical transient receptor potential 1 complex in flow-induced Ca2+ influx.	Ma, X., Qiu, S., Luo, J., Ma, Y., Ngai, C. Y., Shen, B., Wong, C. O., Huang, Y., Yao, X.	Arterioscler Thromb Vasc Biol	2010
20022948	TRPC3 regulates agonist-stimulated Ca2+ mobilization by mediating the interaction between type I inositol 1,4,5-trisphosphate receptor, RACK1, and Orai1.	Woodard, G. E., Lopez, J. J., Jardin, I., Salido, G. M., Rosado, J. A.	J Biol Chem	2010
19996314	Cell-cell contact formation governs Ca2+ signaling by TRPC4 in the vascular endothelium: evidence for a regulatory TRPC4-beta-catenin interaction.	Graziani, A., Poteser, M., Heupel, W. M., Schleifer, H., Krenn, M., Drenckhahn, D., Romanin, C., Baumgartner, W., Groschner, K.	J Biol Chem	2010
19945390	Peptidyl-prolyl isomerase FKBP52 controls chemotropic guidance of neuronal growth cones via regulation of TRPC1 channel opening.	Shim, S., Yuan, J. P., Kim, J. Y., Zeng, W., Huang, G., Milshteyn, A., Kern, D., Muallem, S., Ming, G. L., Worley, P. F.	Neuron	2009
19932145	The interactions of the C-terminal region of the TRPC6 channel with calmodulin.	Friedlova, E., Grycova, L., Holakovska, B., Silhan, J., Janouskova, H., Sulc, M., Obsilova, V., Obsil, T., Teisinger, J.	Neurochem Int	2010
19897728	Activation of TRPC1 by STIM1 in ER-PM microdomains involves release of the channel from its scaffold caveolin-1.	Pani, B., Ong, H. L., Brazer, S. C., Liu, X., Rauser, K., Singh, B. B., Ambudkar, I. S.	Proc Natl Acad Sci U S A	2009
19885840	Functional multimerization of mucolipin channel proteins.	Curcio-Morelli, C., Zhang, P., Venugopal, B., Charles, F. A., Browning, M. F., Cantiello, H. F., Slaugenhaupt, S. A.	J Cell Physiol	2010
19879844	Polycystin-1 and -2 dosage regulates pressure sensing.	Sharif-Naeini, R., Folgering, J. H., Bichet, D., Duprat, F., Lauritzen, I., Arhatte, M., Jodar, M., Dedman, A., Chatelain, F. C., Schulte, U., Retailleau, K., Loufrani, L., Patel, A., Sachs, F., Delmas, P., Peters, D. J., Honore, E.	Cell	2009
19864432	Differential regulation of TRPV1, TRPV3, and TRPV4 sensitivity through a conserved binding site on the ankyrin repeat domain.	Phelps, C. B., Wang, R. R., Choo, S. S., Gaudet, R.	J Biol Chem	2010
19864416	Identification of the penta-EF-hand protein ALG-2 as a Ca2+-dependent interactor of mucolipin-1.	Vergarajauregui, S., Martina, J. A., Puertollano, R.	J Biol Chem	2009
19850920	The transient receptor potential channels TRPP2 and TRPC1 form a heterotetramer with a 2:2 stoichiometry and an alternating subunit arrangement.	Kobori, T., Smith, G. D., Sandford, R., Edwardson, J. M.	J Biol Chem	2009
19812035	A pathogenic C terminus-truncated polycystin-2 mutant enhances receptor-activated Ca2+ entry via association with TRPC3 and TRPC7.	Miyagi, K., Kiyonaka, S., Yamada, K., Miki, T., Mori, E., Kato, K., Numata, T., Sawaguchi, Y., Numaga, T., Kimura, T., Kanai, Y., Kawano, M., Wakamori, M., Nomura, H., Koni, I., Yamagishi, M., Mori, Y.	J Biol Chem	2009
19812031	Regulation of TRPC1 and TRPC4 cation channels requires an alpha1-syntrophin-dependent complex in skeletal mouse myotubes.	Sabourin, J., Lamiche, C., Vandebrouck, A., Magaud, C., Rivet, J., Cognard, C., Bourmeyster, N., Constantin, B.	J Biol Chem	2009
19801576	PRKCSH/80K-H, the protein mutated in polycystic liver disease, protects polycystin-2/TRPP2 against HERP-mediated degradation.	Gao, H., Wang, Y., Wegierski, T., Skouloudaki, K., Putz, M., Fu, X., Engel, C., Boehlke, C., Peng, H., Kuehn, E. W., Kim, E., Kramer-Zucker, A., Walz, G.	Hum Mol Genet	2010
19726544	Analysis of the cytoplasmic interaction between polycystin-1 and polycystin-2.	Casuscelli, J., Schmidt, S., DeGray, B., Petri, E. T., Celic, A., Folta-Stogniew, E., Ehrlich, B. E., Boggon, T. J.	Am J Physiol Renal Physiol	2009
19689790	Abnormal expression, localization and interaction of canonical transient receptor potential ion channels in human breast cancer cell lines and tissues: a potential target for breast cancer diagnosis and therapy.	Aydar, E., Yeo, S., Djamgoz, M., Palmer, C.	Cancer Cell Int	2009
19557826	A potentially dynamic lysosomal role for the endogenous TRPML proteins.	Zeevi, D. A., Frumkin, A., Offen-Glasner, V., Kogot-Levin, A., Bach, G.	J Pathol	2009
19556541	Structural and molecular basis of the assembly of the TRPP2/PKD1 complex.	Yu, Y., Ulbrich, M. H., Li, M. H., Buraei, Z., Chen, X. Z., Ong, A. C., Tong, L., Isacoff, E. Y., Yang, J.	Proc Natl Acad Sci U S A	2009
19522758	The Ca(2+) channel TRPML3 regulates membrane trafficking and autophagy.	Kim, H. J., Soyombo, A. A., Tjon-Kon-Sang, S., So, I., Muallem, S.	Traffic	2009
19502552	Inhibition of TRPC1/TRPC3 by PKG contributes to NO-mediated vasorelaxation.	Chen, J., Crossland, R. F., Noorani, M. M., Marrelli, S. P.	Am J Physiol Heart Circ Physiol	2009
19351713	Regulation of transient receptor potential canonical channel 1 (TRPC1) by sphingosine 1-phosphate in C2C12 myoblasts and its relevance for a role of mechanotransduction in skeletal muscle differentiation.	Formigli, L., Sassoli, C., Squecco, R., Bini, F., Martinesi, M., Chellini, F., Luciani, G., Sbrana, F., Zecchi-Orlandini, S., Francini, F., Meacci, E.	J Cell Sci	2009
19332490	TRPC1 and STIM1 mediate capacitative Ca2+ entry in mouse pulmonary arterial smooth muscle cells.	Ng, L. C., McCormack, M. D., Airey, J. A., Singer, C. A., Keller, P. S., Shen, X. M., Hume, J. R.	J Physiol	2009
19329436	Regulation of the epithelial Mg2+ channel TRPM6 by estrogen and the associated repressor protein of estrogen receptor activity (REA).	Cao, G., van der Wijst, J., van der Kemp, A., van Zeeland, F., Bindels, R. J., Hoenderop, J. G.	J Biol Chem	2009
19307462	Interaction between TRPC1/TRPC4 assembly and STIM1 contributes to store-operated Ca2+ entry in mesangial cells.	Sours-Brothers, S., Ding, M., Graham, S., Ma, R.	Exp Biol Med (Maywood)	2009
19295174	Endogenous expression of TRPV5 and TRPV6 calcium channels in human leukemia K562 cells.	Semenova, S. B., Vassilieva, I. O., Fomina, A. F., Runov, A. L., Negulyaev, Y. A.	Am J Physiol Cell Physiol	2009
19289841	Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound.	Kiyonaka, S., Kato, K., Nishida, M., Mio, K., Numaga, T., Sawaguchi, Y., Yoshida, T., Wakamori, M., Mori, E., Numata, T., Ishii, M., Takemoto, H., Ojida, A., Watanabe, K., Uemura, A., Kurose, H., Morii, T., Kobayashi, T., Sato, Y., Sato, C., Hamachi, I., Mori, Y.	Proc Natl Acad Sci U S A	2009
19277847	Glutamate at position 227 of junctophilin-2 is involved in binding to TRPC3.	Woo, J. S., Hwang, J. H., Ko, J. K., Kim do, H., Ma, J., Lee, E. H.	Mol Cell Biochem	2009
19260825	Dynamic interaction of hTRPC6 with the Orai1-STIM1 complex or hTRPC3 mediates its role in capacitative or non-capacitative Ca(2+) entry pathways.	Jardin, I., Gomez, L. J., Salido, G. M., Rosado, J. A.	Biochem J	2009
19228695	Native Store-operated Ca2+ Influx Requires the Channel Function of Orai1 and TRPC1.	Kim, M. S., Zeng, W., Yuan, J. P., Shin, D. M., Worley, P. F., Muallem, S.	J Biol Chem	2009
19228120	Identification of dimer interactions required for the catalytic activity of the TRPM7 alpha-kinase domain.	Crawley, S. W., Cote, G. P.	Biochem J	2009
19223122	Cross-inhibition between native and recombinant TRPV1 and P2X(3) receptors.	Stanchev, D., Blosa, M., Milius, D., Gerevich, Z., Rubini, P., Schmalzing, G., Eschrich, K., Schaefer, M., Wirkner, K., Illes, P.	Pain	2009
19193631	The multimeric structure of polycystin-2 (TRPP2): structural-functional correlates of homo- and hetero-multimers with TRPC1.	Zhang, P., Luo, Y., Chasan, B., Gonzalez-Perrett, S., Montalbetti, N., Timpanaro, G. A., Cantero Mdel, R., Ramos, A. J., Goldmann, W. H., Zhou, J., Cantiello, H. F.	Hum Mol Genet	2009
19168436	TRPC1 associates with BK(Ca) channel to form a signal complex in vascular smooth muscle cells.	Kwan, H. Y., Shen, B., Ma, X., Kwok, Y. C., Huang, Y., Man, Y. B., Yu, S., Yao, X.	Circ Res	2009
19155296	Transient receptor potential type vanilloid 1 suppresses skin carcinogenesis.	Bode, A. M., Cho, Y. Y., Zheng, D., Zhu, F., Ericson, M. E., Ma, W. Y., Yao, K., Dong, Z.	Cancer Res	2009
19117012	Chaperone-mediated autophagy is defective in mucolipidosis type IV.	Venugopal, B., Mesires, N. T., Kennedy, J. C., Curcio-Morelli, C., Laplante, J. M., Dice, J. F., Slaugenhaupt, S. A.	J Cell Physiol	2009
19074769	TRPC3 activation by erythropoietin is modulated by TRPC6.	Hirschler-Laszkiewicz, I., Tong, Q., Conrad, K., Zhang, W., Flint, W. W., Barber, A. J., Barber, D. L., Cheung, J. Y., Miller, B. A.	J Biol Chem	2009
19052258	Caveolin-1 scaffold domain interacts with TRPC1 and IP3R3 to regulate Ca2+ store release-induced Ca2+ entry in endothelial cells.	Sundivakkam, P. C., Kwiatek, A. M., Sharma, T. T., Minshall, R. D., Malik, A. B., Tiruppathi, C.	Am J Physiol Cell Physiol	2009
19052171	Canonical transient receptor potential channel (TRPC)3 and TRPC6 associate with large-conductance Ca2+-activated K+ (BKCa) channels: role in BKCa trafficking to the surface of cultured podocytes.	Kim, E. Y., Alvarez-Baron, C. P., Dryer, S. E.	Mol Pharmacol	2009
19033444	Tyrosine phosphorylation modulates the activity of TRPV4 in response to defined stimuli.	Wegierski, T., Lewandrowski, U., Muller, B., Sickmann, A., Walz, G.	J Biol Chem	2009
19027987	Functional interaction of the cation channel transient receptor potential vanilloid 4 (TRPV4) and actin in volume regulation.	Becker, D., Bereiter-Hahn, J., Jendrach, M.	Eur J Cell Biol	2009
18836075	Syntaxin 5 regulates the endoplasmic reticulum channel-release properties of polycystin-2.	Geng, L., Boehmerle, W., Maeda, Y., Okuhara, D. Y., Tian, X., Yu, Z., Choe, C. U., Anyatonwu, G. I., Ehrlich, B. E., Somlo, S.	Proc Natl Acad Sci U S A	2008
18826956	IP3 receptor binds to and sensitizes TRPV4 channel to osmotic stimuli via a calmodulin-binding site.	Garcia-Elias, A., Lorenzo, I. M., Vicente, R., Valverde, M. A.	J Biol Chem	2008
18802106	Secretogranin III directs secretory vesicle biogenesis in mast cells in a manner dependent upon interaction with chromogranin A.	Prasad, P., Yanagihara, A. A., Small-Howard, A. L., Turner, H., Stokes, A. J.	J Immunol	2008
18802022	Interactions, functions, and independence of plasma membrane STIM1 and TRPC1 in vascular smooth muscle cells.	Li, J., Sukumar, P., Milligan, C. J., Kumar, B., Ma, Z. Y., Munsch, C. M., Jiang, L. H., Porter, K. E., Beech, D. J.	Circ Res	2008
18782757	Polycystin-2 expression is regulated by a PC2-binding domain in the intracellular portion of fibrocystin.	Kim, I., Li, C., Liang, D., Chen, X. Z., Coffy, R. J., Ma, J., Zhao, P., Wu, G.	J Biol Chem	2008
18755685	TRPC3 controls agonist-stimulated intracellular Ca2+ release by mediating the interaction between inositol 1,4,5-trisphosphate receptor and RACK1.	Bandyopadhyay, B. C., Ong, H. L., Lockwich, T. P., Liu, X., Paria, B. C., Singh, B. B., Ambudkar, I. S.	J Biol Chem	2008
18701070	Proinflammatory mediators modulate the heat-activated ion channel TRPV1 via the scaffolding protein AKAP79/150.	Zhang, X., Li, L., McNaughton, P. A.	Neuron	2008
18695040	TRPP2 and TRPV4 form a polymodal sensory channel complex.	Kottgen, M., Buchholz, B., Garcia-Gonzalez, M. A., Kotsis, F., Fu, X., Doerken, M., Boehlke, C., Steffl, D., Tauber, R., Wegierski, T., Nitschke, R., Suzuki, M., Kramer-Zucker, A., Germino, G. G., Watnick, T., Prenen, J., Nilius, B., Kuehn, E. W., Walz, G.	J Cell Biol	2008
18664456	Polycystin-2 down-regulates cell proliferation via promoting PERK-dependent phosphorylation of eIF2alpha.	Liang, G., Yang, J., Wang, Z., Li, Q., Tang, Y., Chen, X. Z.	Hum Mol Genet	2008
18644792	Orai1 mediates the interaction between STIM1 and hTRPC1 and regulates the mode of activation of hTRPC1-forming Ca2+ channels.	Jardin, I., Lopez, J. J., Salido, G. M., Rosado, J. A.	J Biol Chem	2008
18617565	Nitric oxide-cGMP-protein kinase G pathway negatively regulates vascular transient receptor potential channel TRPC6.	Takahashi, S., Lin, H., Geshi, N., Mori, Y., Kawarabayashi, Y., Takami, N., Mori, M. X., Honda, A., Inoue, R.	J Physiol	2008
18606998	Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1.	Cha, S. K., Ortega, B., Kurosu, H., Rosenblatt, K. P., Kuro-O, M., Huang, C. L.	Proc Natl Acad Sci U S A	2008
18544631	TRPC1 binds to caveolin-3 and is regulated by Src kinase - role in Duchenne muscular dystrophy.	Gervasio, O. L., Whitehead, N. P., Yeung, E. W., Phillips, W. D., Allen, D. G.	J Cell Sci	2008
18535624	Off-response property of an acid-activated cation channel complex PKD1L3-PKD2L1.	Inada, H., Kawabata, F., Ishimaru, Y., Fushiki, T., Matsunami, H., Tominaga, M.	EMBO Rep	2008
18502908	ATP/UTP activate cation-permeable channels with TRPC3/7 properties in rat cardiomyocytes.	Alvarez, J., Coulombe, A., Cazorla, O., Ugur, M., Rauzier, J. M., Magyar, J., Mathieu, E. L., Boulay, G., Souto, R., Bideaux, P., Salazar, G., Rassendren, F., Lacampagne, A., Fauconnier, J., Vassort, G.	Am J Physiol Heart Circ Physiol	2008
18495742	The beta-glucuronidase klotho exclusively activates the epithelial Ca2+ channels TRPV5 and TRPV6.	Lu, P., Boros, S., Chang, Q., Bindels, R. J., Hoenderop, J. G.	Nephrol Dial Transplant	2008
18463244	Protein kinase A anchoring via AKAP150 is essential for TRPV1 modulation by forskolin and prostaglandin E2 in mouse sensory neurons.	Schnizler, K., Shutov, L. P., Van Kanegan, M. J., Merrill, M. A., Nichols, B., McKnight, G. S., Strack, S., Hell, J. W., Usachev, Y. M.	J Neurosci	2008
18455988	Pirt, a phosphoinositide-binding protein, functions as a regulatory subunit of TRPV1.	Kim, A. Y., Tang, Z., Liu, Q., Patel, K. N., Maag, D., Geng, Y., Dong, X.	Cell	2008
18445599	The human TRPV6 channel protein is associated with cyclophilin B in human placenta.	Stumpf, T., Zhang, Q., Hirnet, D., Lewandrowski, U., Sickmann, A., Wissenbach, U., Dorr, J., Lohr, C., Deitmer, J. W., Fecher-Trost, C.	J Biol Chem	2008
18430726	Lipid rafts determine clustering of STIM1 in endoplasmic reticulum-plasma membrane junctions and regulation of store-operated Ca2+ entry (SOCE).	Pani, B., Ong, H. L., Liu, X., Rauser, K., Ambudkar, I. S., Singh, B. B.	J Biol Chem	2008
18392847	Identification of Nipsnap1 as a novel auxiliary protein inhibiting TRPV6 activity.	Schoeber, J. P., Topala, C. N., Lee, K. P., Lambers, T. T., Ricard, G., van der Kemp, A. W., Huynen, M. A., Hoenderop, J. G., Bindels, R. J.	Pflugers Arch	2008
18381233	A-kinase anchoring protein mediates TRPV1 thermal hyperalgesia through PKA phosphorylation of TRPV1.	Jeske, N. A., Diogenes, A., Ruparel, N. B., Fehrenbacher, J. C., Henry, M., Akopian, A. N., Hargreaves, K. M.	Pain	2008
18378772	IP3 sensitizes TRPV4 channel to the mechano- and osmotransducing messenger 5'-6'-epoxyeicosatrienoic acid.	Fernandes, J., Lorenzo, I. M., Andrade, Y. N., Garcia-Elias, A., Serra, S. A., Fernandez-Fernandez, J. M., Valverde, M. A.	J Cell Biol	2008
18356201	Diverse properties of store-operated TRPC channels activated by protein kinase C in vascular myocytes.	Saleh, S. N., Albert, A. P., Peppiatt-Wildman, C. M., Large, W. A.	J Physiol	2008
18326500	Functional requirement for Orai1 in store-operated TRPC1-STIM1 channels.	Cheng, K. T., Liu, X., Ong, H. L., Ambudkar, I. S.	J Biol Chem	2008
18323855	Formation of a new receptor-operated channel by heteromeric assembly of TRPP2 and TRPC1 subunits.	Bai, C. X., Giamarchi, A., Rodat-Despoix, L., Padilla, F., Downs, T., Tsiokas, L., Delmas, P.	EMBO Rep	2008
18287061	Functional interactions among Orai1, TRPCs, and STIM1 suggest a STIM-regulated heteromeric Orai/TRPC model for SOCE/Icrac channels.	Liao, Y., Erxleben, C., Abramowitz, J., Flockerzi, V., Zhu, M. X., Armstrong, D. L., Birnbaumer, L.	Proc Natl Acad Sci U S A	2008
18276585	TRPC3 is the erythropoietin-regulated calcium channel in human erythroid cells.	Tong, Q., Hirschler-Laszkiewicz, I., Zhang, W., Conrad, K., Neagley, D. W., Barber, D. L., Cheung, J. Y., Miller, B. A.	J Biol Chem	2008
18273441	Kidney injury molecule 1 (Kim1) is a novel ciliary molecule and interactor of polycystin 2.	Kuehn, E. W., Hirt, M. N., John, A. K., Muehlenhardt, P., Boehlke, C., Putz, M., Kramer-Zucker, A. G., Bashkurov, M., van de Weyer, P. S., Kotsis, F., Walz, G.	Biochem Biophys Res Commun	2007
18268005	Mice lacking Homer 1 exhibit a skeletal myopathy characterized by abnormal transient receptor potential channel activity.	Stiber, J. A., Zhang, Z. S., Burch, J., Eu, J. P., Zhang, S., Truskey, G. A., Seth, M., Yamaguchi, N., Meissner, G., Shah, R., Worley, P. F., Williams, R. S., Rosenberg, P. B.	Mol Cell Biol	2008
18262493	TRPM4b channel suppresses store-operated Ca2+ entry by a novel protein-protein interaction with the TRPC3 channel.	Park, J. Y., Hwang, E. M., Yarishkin, O., Seo, J. H., Kim, E., Yoo, J., Yi, G. S., Kim, D. G., Park, N., Ha, C. M., La, J. H., Kang, D., Han, J., Oh, U., Hong, S. G.	Biochem Biophys Res Commun	2008
18261457	Interaction with dopamine D2 receptor enhances expression of transient receptor potential channel 1 at the cell surface.	Hannan, M. A., Kabbani, N., Paspalas, C. D., Levenson, R.	Biochim Biophys Acta	2008
18258429	RACK1 inhibits TRPM6 activity via phosphorylation of the fused alpha-kinase domain.	Cao, G., Thebault, S., van der Wijst, J., van der Kemp, A., Lasonder, E., Bindels, R. J., Hoenderop, J. G.	Curr Biol	2008
18256307	Mediation of angiotensin II-induced Ca2+ signaling by polycystin 2 in glomerular mesangial cells.	Du, J., Ding, M., Sours-Brothers, S., Graham, S., Ma, R.	Am J Physiol Renal Physiol	2008
18249094	Functional relevance of the de novo coupling between hTRPC1 and type II IP3 receptor in store-operated Ca2+ entry in human platelets.	Jardin, I., Lopez, J. J., Salido, G. M., Rosado, J. A.	Cell Signal	2008
18235101	Nek8 regulates the expression and localization of polycystin-1 and polycystin-2.	Sohara, E., Luo, Y., Zhang, J., Manning, D. K., Beier, D. R., Zhou, J.	J Am Soc Nephrol	2008
18235088	Fibrocystin/polyductin modulates renal tubular formation by regulating polycystin-2 expression and function.	Kim, I., Fu, Y., Hui, K., Moeckel, G., Mai, W., Li, C., Liang, D., Zhao, P., Ma, J., Chen, X. Z., George, A. L. Jr, Coffey, R. J., Feng, Z. P., Wu, G.	J Am Soc Nephrol	2008
18234883	Interaction of transient receptor potential vanilloid 4, integrin, and SRC tyrosine kinase in mechanical hyperalgesia.	Alessandri-Haber, N., Dina, O. A., Joseph, E. K., Reichling, D. B., Levine, J. D.	J Neurosci	2008
18215135	TRPC3-interacting triadic proteins in skeletal muscle.	Woo, J. S., Kim do, H., Allen, P. D., Lee, E. H.	Biochem J	2008
18205297	Analysis of TRPC3-interacting proteins by tandem mass spectrometry.	Lockwich, T., Pant, J., Makusky, A., Jankowska-Stephens, E., Kowalak, J. A., Markey, S. P., Ambudkar, I. S.	J Proteome Res	2008
18191041	Intracellular Ca2+ store depletion induces the formation of macromolecular complexes involving hTRPC1, hTRPC6, the type II IP3 receptor and SERCA3 in human platelets.	Redondo, P. C., Jardin, I., Lopez, J. J., Salido, G. M., Rosado, J. A.	Biochim Biophys Acta	2008
18187190	The annexin 2-S100A10 complex and its association with TRPV6 is regulated by cAMP/PKA/CnA in airway and gut epithelia.	Borthwick, L. A., Neal, A., Hobson, L., Gerke, V., Robson, L., Muimo, R.	Cell Calcium	2008
18178578	Polycystin-2 is regulated by endoplasmic reticulum-associated degradation.	Liang, G., Li, Q., Tang, Y., Kokame, K., Kikuchi, T., Wu, G., Chen, X. Z.	Hum Mol Genet	2008
18174177	Stimulus-specific modulation of the cation channel TRPV4 by PACSIN 3.	D'hoedt, D., Owsianik, G., Prenen, J., Cuajungco, M. P., Grimm, C., Heller, S., Voets, T., Nilius, B.	J Biol Chem	2008
18068335	SERCA2b and 3 play a regulatory role in store-operated calcium entry in human platelets.	Redondo, P. C., Salido, G. M., Pariente, J. A., Sage, S. O., Rosado, J. A.	Cell Signal	2008
18063480	Interaction between protein kinase D1 and transient receptor potential V1 in primary sensory neurons is involved in heat hypersensitivity.	Zhu, H., Yang, Y., Zhang, H., Han, Y., Li, Y., Zhang, Y., Yin, D., He, Q., Zhao, Z., Blumberg, P. M., Han, J., Wang, Y.	Pain	2008
18048348	The spectrin cytoskeleton influences the surface expression and activation of human transient receptor potential channel 4 channels.	Odell, A. F., Van Helden, D. F., Scott, J. L.	J Biol Chem	2008
17988215	Mucolipin 1 channel activity is regulated by protein kinase A-mediated phosphorylation.	Vergarajauregui, S., Oberdick, R., Kiselyov, K., Puertollano, R.	Biochem J	2008
17944866	Direct binding of alpha-actinin enhances TRPP3 channel activity.	Li, Q., Dai, X. Q., Shen, P. Y., Wu, Y., Long, W., Chen, C. X., Hussain, Z., Wang, S., Chen, X. Z.	J Neurochem	2007
17932042	OS-9 regulates the transit and polyubiquitination of TRPV4 in the endoplasmic reticulum.	Wang, Y., Fu, X., Gaiser, S., Kottgen, M., Kramer-Zucker, A., Walz, G., Wegierski, T.	J Biol Chem	2007
17913834	Association of VASP with TRPC4 in PKG-mediated inhibition of the store-operated calcium response in mesangial cells.	Wang, X., Pluznick, J. L., Settles, D. C., Sansom, S. C.	Am J Physiol Renal Physiol	2007
17892531	hTRPC1-associated alpha-actinin, and not hTRPC1 itself, is tyrosine phosphorylated during human platelet activation.	Redondo, P. C., Harper, A. G., Harper, M. T., Brownlow, S. L., Rosado, J. A., Sage, S. O.	J Thromb Haemost	2007
17850865	RNF24, a new TRPC interacting protein, causes the intracellular retention of TRPC.	Lussier, M. P., Lepage, P. K., Bousquet, S. M., Boulay, G.	Cell Calcium	2008
17699554	Vasopressin-induced membrane trafficking of TRPC3 and AQP2 channels in cells of the rat renal collecting duct.	Goel, M., Sinkins, W. G., Zuo, C. D., Hopfer, U., Schilling, W. P.	Am J Physiol Renal Physiol	2007
17684020	Snapin, a new regulator of receptor signaling, augments alpha1A-adrenoceptor-operated calcium influx through TRPC6.	Suzuki, F., Morishima, S., Tanaka, T., Muramatsu, I.	J Biol Chem	2007
17681754	Dual role of tubulin-cytoskeleton in store-operated calcium entry in human platelets.	Redondo, P. C., Harper, A. G., Sage, S. O., Rosado, J. A.	Cell Signal	2007
17645868	PDZ domain-containing protein as a physiological modulator of TRPV6.	Kim, H. J., Yang, D. K., So, I.	Biochem Biophys Res Commun	2007
17636028	TAZ promotes PC2 degradation through a SCFbeta-Trcp E3 ligase complex.	Tian, Y., Kolb, R., Hong, J. H., Carroll, J., Li, D., You, J., Bronson, R., Yaffe, M. B., Zhou, J., Benjamin, T.	Mol Cell Biol	2007
17624425	The first ankyrin-like repeat is the minimum indispensable key structure for functional assembly of homo- and heteromeric TRPC4/TRPC5 channels.	Schindl, R., Frischauf, I., Kahr, H., Fritsch, R., Krenn, M., Derndl, A., Vales, E., Muik, M., Derler, I., Groschner, K., Romanin, C.	Cell Calcium	2008
17620599	Functional specialization of beta-arrestin interactions revealed by proteomic analysis.	Xiao, K., McClatchy, D. B., Shukla, A. K., Zhao, Y., Chen, M., Shenoy, S. K., Yates, J. R. 3rd, Lefkowitz, R. J.	Proc Natl Acad Sci U S A	2007
17486119	STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels.	Yuan, J. P., Zeng, W., Huang, G. N., Worley, P. F., Muallem, S.	Nat Cell Biol	2007
17416589	Genetic evidence supporting caveolae microdomain regulation of calcium entry in endothelial cells.	Murata, T., Lin, M. I., Stan, R. V., Bauer, P. M., Yu, J., Sessa, W. C.	J Biol Chem	2007
17404231	Regulation of ryanodine receptor-dependent calcium signaling by polycystin-2.	Anyatonwu, G. I., Estrada, M., Tian, X., Somlo, S., Ehrlich, B. E.	Proc Natl Acad Sci U S A	2007
17360584	Orai proteins interact with TRPC channels and confer responsiveness to store depletion.	Liao, Y., Erxleben, C., Yildirim, E., Abramowitz, J., Armstrong, D. L., Birnbaumer, L.	Proc Natl Acad Sci U S A	2007
17298389	Identification and characterisation of novel tubulin-binding motifs located within the C-terminus of TRPV1.	Goswami, C., Hucho, T. B., Hucho, F.	J Neurochem	2007
17283055	Fibrocystin/polyductin, found in the same protein complex with polycystin-2, regulates calcium responses in kidney epithelia.	Wang, S., Zhang, J., Nauli, S. M., Li, X., Starremans, P. G., Luo, Y., Roberts, K. A., Zhou, J.	Mol Cell Biol	2007
17251321	Regulation of TRP channel TRPM2 by the tyrosine phosphatase PTPL1.	Zhang, W., Tong, Q., Conrad, K., Wozney, J., Cheung, J. Y., Miller, B. A.	Am J Physiol Cell Physiol	2007
17224452	Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx. Evidence for similarities in store-operated and calcium release-activated calcium channel components.	Ong, H. L., Cheng, K. T., Liu, X., Bandyopadhyay, B. C., Paria, B. C., Soboloff, J., Pani, B., Gwack, Y., Srikanth, S., Singh, B. B., Gill, D. L., Ambudkar, I. S.	J Biol Chem	2007
17202249	Regulation of capacitative calcium entries by alpha1-syntrophin: association of TRPC1 with dystrophin complex and the PDZ domain of alpha1-syntrophin.	Vandebrouck, A., Sabourin, J., Rivet, J., Balghi, H., Sebille, S., Kitzis, A., Raymond, G., Cognard, C., Bourmeyster, N., Constantin, B.	FASEB J	2007
17197020	Identification of tyrosines in the putative regulatory site of the Ca2+ channel TRPV6.	Sternfeld, L., Anderie, I., Schmid, A., Al-Shaldi, H., Krause, E., Magg, T., Schreiner, D., Hofer, H. W., Schulz, I.	Cell Calcium	2007
17194758	Cyclin-dependent kinase 5 modulates nociceptive signaling through direct phosphorylation of transient receptor potential vanilloid 1.	Pareek, T. K., Keller, J., Kesavapany, S., Agarwal, N., Kuner, R., Pant, H. C., Iadarola, M. J., Brady, R. O., Kulkarni, A. B.	Proc Natl Acad Sci U S A	2007
17156765	Insulin potentiates TRPC3-mediated cation currents in normal but not in insulin-resistant mouse cardiomyocytes.	Fauconnier, J., Lanner, J. T., Sultan, A., Zhang, S. J., Katz, A., Bruton, J. D., Westerblad, H.	Cardiovasc Res	2007
17129578	Phospholipase C-dependent control of cardiac calcium homeostasis involves a TRPC3-NCX1 signaling complex.	Eder, P., Probst, D., Rosker, C., Poteser, M., Wolinski, H., Kohlwein, S. D., Romanin, C., Groschner, K.	Cardiovasc Res	2007
17110928	The HECT ubiquitin ligase AIP4 regulates the cell surface expression of select TRP channels.	Wegierski, T., Hill, K., Schaefer, M., Walz, G.	EMBO J	2006
17088214	The TRPM7 ion channel functions in cholinergic synaptic vesicles and affects transmitter release.	Krapivinsky, G., Mochida, S., Krapivinsky, L., Cibulsky, S. M., Clapham, D. E.	Neuron	2006
17074976	Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane.	Stein, A. T., Ufret-Vincenty, C. A., Hua, L., Santana, L. F., Gordon, S. E.	J Gen Physiol	2006
17012351	TRPC3 channels colocalize with Na+/Ca2+ exchanger and Na+ pump in axial component of transverse-axial tubular system of rat ventricle.	Goel, M., Zuo, C. D., Sinkins, W. G., Schilling, W. P.	Am J Physiol Heart Circ Physiol	2007
17008358	Kinesin-2 mediates physical and functional interactions between polycystin-2 and fibrocystin.	Wu, Y., Dai, X. Q., Li, Q., Chen, C. X., Mai, W., Hussain, Z., Long, W., Montalbetti, N., Li, G., Glynne, R., Wang, S., Cantiello, H. F., Wu, G., Chen, X. Z.	Hum Mol Genet	2006
16959851	Dynamic but not constitutive association of calmodulin with rat TRPV6 channels enables fine tuning of Ca2+-dependent inactivation.	Derler, I., Hofbauer, M., Kahr, H., Fritsch, R., Muik, M., Kepplinger, K., Hack, M. E., Moritz, S., Schindl, R., Groschner, K., Romanin, C.	J Physiol	2006
16950792	Polycystin-2 cation channel function is under the control of microtubular structures in primary cilia of renal epithelial cells.	Li, Q., Montalbetti, N., Wu, Y., Ramos, A., Raychowdhury, M. K., Chen, X. Z., Cantiello, H. F.	J Biol Chem	2006
16916799	Identification of two domains involved in the assembly of transient receptor potential canonical channels.	Lepage, P. K., Lussier, M. P., Barajas-Martinez, H., Bousquet, S. M., Blanchard, A. P., Francoeur, N., Dumaine, R., Boulay, G.	J Biol Chem	2006
16906149	STIM1 carboxyl-terminus activates native SOC, I(crac) and TRPC1 channels.	Huang, G. N., Zeng, W., Kim, J. Y., Yuan, J. P., Han, L., Muallem, S., Worley, P. F.	Nat Cell Biol	2006
16905188	Signaling proteins in raft-like microdomains are essential for Ca2+ wave propagation in glial cells.	Weerth, S. H., Holtzclaw, L. A., Russell, J. T.	Cell Calcium	2007
16899571	Pregnancy-enhanced store-operated Ca2+ channel function in uterine artery endothelial cells is associated with enhanced agonist-specific transient receptor potential channel 3-inositol 1,4,5-trisphosphate receptor 2 interaction.	Gifford, S. M., Yi, F. X., Bird, I. M.	J Endocrinol	2006
16895908	RGS2 inhibits the epithelial Ca2+ channel TRPV6.	Schoeber, J. P., Topala, C. N., Wang, X., Diepens, R. J., Lambers, T. T., Hoenderop, J. G., Bindels, R. J.	J Biol Chem	2006
16891422	Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor.	Ishimaru, Y., Inada, H., Kubota, M., Zhuang, H., Tominaga, M., Matsunami, H.	Proc Natl Acad Sci U S A	2006
16887806	Homer 1 mediates store- and inositol 1,4,5-trisphosphate receptor-dependent translocation and retrieval of TRPC3 to the plasma membrane.	Kim, J. Y., Zeng, W., Kiselyov, K., Yuan, J. P., Dehoff, M. H., Mikoshiba, K., Worley, P. F., Muallem, S.	J Biol Chem	2006
16875688	Identification and characterization of GSRP-56, a novel Golgi-localized spectrin repeat-containing protein.	Kobayashi, Y., Katanosaka, Y., Iwata, Y., Matsuoka, M., Shigekawa, M., Wakabayashi, S.	Exp Cell Res	2006
16870612	Interaction of STIM1 with endogenously expressed human canonical TRP1 upon depletion of intracellular Ca2+ stores.	Lopez, J. J., Salido, G. M., Pariente, J. A., Rosado, J. A.	J Biol Chem	2006
16822931	Caveolin-1 regulates store-operated Ca2+ influx by binding of its scaffolding domain to transient receptor potential channel-1 in endothelial cells.	Kwiatek, A. M., Minshall, R. D., Cool, D. R., Skidgel, R. A., Malik, A. B., Tiruppathi, C.	Mol Pharmacol	2006
16818374	Interaction between TRPC channel subunits in endothelial cells.	Antoniotti, S., Fiorio Pla, A., Barral, S., Scalabrino, O., Munaron, L., Lovisolo, D.	J Recept Signal Transduct Res	2006
16763551	Calbindin-D28K dynamically controls TRPV5-mediated Ca2+ transport.	Lambers, T. T., Mahieu, F., Oancea, E., Hoofd, L., de Lange, F., Mensenkamp, A. R., Voets, T., Nilius, B., Clapham, D. E., Hoenderop, J. G., Bindels, R. J.	EMBO J	2006
16627472	PACSINs bind to the TRPV4 cation channel. PACSIN 3 modulates the subcellular localization of TRPV4.	Cuajungco, M. P., Grimm, C., Oshima, K., D'hoedt, D., Nilius, B., Mensenkamp, A. R., Bindels, R. J., Plomann, M., Heller, S.	J Biol Chem	2006
16609150	More than colocalizing with polycystin-1, polycystin-L is in the centrosome.	Bui-Xuan, E. F., Li, Q., Chen, X. Z., Boucher, C. A., Sandford, R., Zhou, J., Basora, N.	Am J Physiol Renal Physiol	2006
16606612	Lysosomal localization of TRPML3 depends on TRPML2 and the mucolipidosis-associated protein TRPML1.	Venkatachalam, K., Hofmann, T., Montell, C.	J Biol Chem	2006
16571723	A role for AQP5 in activation of TRPV4 by hypotonicity: concerted involvement of AQP5 and TRPV4 in regulation of cell volume recovery.	Liu, X., Bandyopadhyay, B. C., Nakamoto, T., Singh, B., Liedtke, W., Melvin, J. E., Ambudkar, I.	J Biol Chem	2006
16565876	Interaction of the epithelial Ca2+ channels TRPV5 and TRPV6 with the intestine- and kidney-enriched PDZ protein NHERF4.	van de Graaf, S. F., Hoenderop, J. G., van der Kemp, A. W., Gisler, S. M., Bindels, R. J.	Pflugers Arch	2006
16537542	TRPC3 and TRPC4 associate to form a redox-sensitive cation channel. Evidence for expression of native TRPC3-TRPC4 heteromeric channels in endothelial cells.	Poteser, M., Graziani, A., Rosker, C., Eder, P., Derler, I., Kahr, H., Zhu, M. X., Romanin, C., Groschner, K.	J Biol Chem	2006
16510717	TRPV1 recapitulates native capsaicin receptor in sensory neurons in association with Fas-associated factor 1.	Kim, S., Kang, C., Shin, C. Y., Hwang, S. W., Yang, Y. D., Shim, W. S., Park, M. Y., Kim, E., Kim, M., Kim, B. M., Cho, H., Shin, Y., Oh, U.	J Neurosci	2006
16500902	Structural characterization of the split pleckstrin homology domain in phospholipase C-gamma1 and its interaction with TRPC3.	Wen, W., Yan, J., Zhang, M.	J Biol Chem	2006
16500080	TRPA1 is a substrate for de-ubiquitination by the tumor suppressor CYLD.	Stokes, A., Wakano, C., Koblan-Huberson, M., Adra, C. N., Fleig, A., Turner, H.	Cell Signal	2006
16469785	Calcium-sensing mechanism in TRPC5 channels contributing to retardation of neurite outgrowth.	Hui, H., McHugh, D., Hannan, M., Zeng, F., Xu, S. Z., Khan, S. U., Levenson, R., Beech, D. J., Weiss, J. L.	J Physiol	2006
16461353	Regulation of the transient receptor potential channel TRPM2 by the Ca2+ sensor calmodulin.	Tong, Q., Zhang, W., Conrad, K., Mostoller, K., Cheung, J. Y., Peterson, B. Z., Miller, B. A.	J Biol Chem	2006
16418302	Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells.	Sours, S., Du, J., Chu, S., Ding, M., Zhou, X. J., Ma, R.	Am J Physiol Renal Physiol	2006
16407977	TRPM7, a novel regulator of actomyosin contractility and cell adhesion.	Clark, K., Langeslag, M., van Leeuwen, B., Ran, L., Ryazanov, A. G., Figdor, C. G., Moolenaar, W. H., Jalink, K., van Leeuwen, F. N.	EMBO J	2006
16407161	Role of Src in C3 transient receptor potential channel function and evidence for a heterogeneous makeup of receptor- and store-operated Ca2+ entry channels.	Kawasaki, B. T., Liao, Y., Birnbaumer, L.	Proc Natl Acad Sci U S A	2006
16380433	Identification of BSPRY as a novel auxiliary protein inhibiting TRPV5 activity.	van de Graaf, S. F., van der Kemp, A. W., van den Berg, D., van Oorschot, M., Hoenderop, J. G., Bindels, R. J.	J Am Soc Nephrol	2006
16354700	Direct interaction with Rab11a targets the epithelial Ca2+ channels TRPV5 and TRPV6 to the plasma membrane.	van de Graaf, S. F., Chang, Q., Mensenkamp, A. R., Hoenderop, J. G., Bindels, R. J.	Mol Cell Biol	2006
16352746	The immunophilin FKBP52 inhibits the activity of the epithelial Ca2+ channel TRPV5.	Gkika, D., Topala, C. N., Hoenderop, J. G., Bindels, R. J.	Am J Physiol Renal Physiol	2006
16319926	NGF rapidly increases membrane expression of TRPV1 heat-gated ion channels.	Zhang, X., Huang, J., McNaughton, P. A.	EMBO J	2005
16311606	Polycystin-1 and polycystin-2 regulate the cell cycle through the helix-loop-helix inhibitor Id2.	Li, X., Luo, Y., Starremans, P. G., McNamara, C. A., Pei, Y., Zhou, J.	Nat Cell Biol	2005
16270640	Transient receptor potential protein subunit assembly and membrane distribution in human platelets.	Brownlow, S. L., Sage, S. O.	Thromb Haemost	2005
16254212	Activation of the endothelial store-operated ISOC Ca2+ channel requires interaction of protein 4.1 with TRPC4.	Cioffi, D. L., Wu, S., Alexeyev, M., Goodman, S. R., Zhu, M. X., Stevens, T.	Circ Res	2005
16239475	The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel.	Chang, Q., Hoefs, S., van der Kemp, A. W., Topala, C. N., Bindels, R. J., Hoenderop, J. G.	Science	2005
16237318	Heteromerization and colocalization of TrpV1 and TrpV2 in mammalian cell lines and rat dorsal root ganglia.	Rutter, A. R., Ma, Q. P., Leveridge, M., Bonnert, T. P.	Neuroreport	2005
16223735	Polycystin 2 interacts with type I inositol 1,4,5-trisphosphate receptor to modulate intracellular Ca2+ signaling.	Li, Y., Wright, J. M., Qian, F., Germino, G. G., Guggino, W. B.	J Biol Chem	2005
16189514	Towards a proteome-scale map of the human protein-protein interaction network.	Rual, J. F., Venkatesan, K., Hao, T., Hirozane-Kishikawa, T., Dricot, A., Li, N., Berriz, G. F., Gibbons, F. D., Dreze, M., Ayivi-Guedehoussou, N., Klitgord, N., Simon, C., Boxem, M., Milstein, S., Rosenberg, J., Goldberg, D. S., Zhang, L. V., Wong, S. L., Franklin, G., Li, S., Albala, J. S., Lim, J., Fraughton, C., Llamosas, E., Cevik, S., Bex, C., Lamesch, P., Sikorski, R. S., Vandenhaute, J., Zoghbi, H. Y., Smolyar, A., Bosak, S., Sequerra, R., Doucette-Stamm, L., Cusick, M. E., Hill, D. E., Roth, F. P., Vidal, M.	Nature	2005
16169070	A human protein-protein interaction network: a resource for annotating the proteome.	Stelzl, U., Worm, U., Lalowski, M., Haenig, C., Brembeck, F. H., Goehler, H., Stroedicke, M., Zenkner, M., Schoenherr, A., Koeppen, S., Timm, J., Mintzlaff, S., Abraham, C., Bock, N., Kietzmann, S., Goedde, A., Toksoz, E., Droege, A., Krobitsch, S., Korn, B., Birchmeier, W., Lehrach, H., Wanker, E. E.	Cell	2005
16153633	Junctate, an inositol 1,4,5-triphosphate receptor associated protein, is present in rodent sperm and binds TRPC2 and TRPC5 but not TRPC1 channels.	Stamboulian, S., Moutin, M. J., Treves, S., Pochon, N., Grunwald, D., Zorzato, F., De Waard, M., Ronjat, M., Arnoult, C.	Dev Biol	2005
16144838	Epidermal growth factor induces tyrosine phosphorylation, membrane insertion, and activation of transient receptor potential channel 4.	Odell, A. F., Scott, J. L., Van Helden, D. F.	J Biol Chem	2005
16135816	PKD2 functions as an epidermal growth factor-activated plasma membrane channel.	Ma, R., Li, W. P., Rundle, D., Kong, J., Akbarali, H. I., Tsiokas, L.	Mol Cell Biol	2005
16115206	Extensive co-localization and heteromultimer formation of the vanilloid receptor-like protein TRPV2 and the capsaicin receptor TRPV1 in the adult rat cerebral cortex.	Liapi, A., Wood, J. N.	Eur J Neurosci	2005
16025302	Proteomic analysis of TRPC5- and TRPC6-binding partners reveals interaction with the plasmalemmal Na(+)/K(+)-ATPase.	Goel, M., Sinkins, W., Keightley, A., Kinter, M., Schilling, W. P.	Pflugers Arch	2005
15994335	Activation of M1 muscarinic acetylcholine receptors stimulates the formation of a multiprotein complex centered on TRPC6 channels.	Kim, J. Y., Saffen, D.	J Biol Chem	2005
15987684	Calmodulin and calcium interplay in the modulation of TRPC5 channel activity. Identification of a novel C-terminal domain for calcium/calmodulin-mediated facilitation.	Ordaz, B., Tang, J., Xiao, R., Salgado, A., Sampieri, A., Zhu, M. X., Vaca, L.	J Biol Chem	2005
15972814	Endogenous TRPC1, TRPC3, and TRPC7 proteins combine to form native store-operated channels in HEK-293 cells.	Zagranichnaya, T. K., Wu, X., Villereal, M. L.	J Biol Chem	2005
15935109	Plasma membrane localization and function of TRPC1 is dependent on its interaction with beta-tubulin in retinal epithelium cells.	Bollimuntha, S., Cornatzer, E., Singh, B. B.	Vis Neurosci	2005
15924139	TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function.	Reiser, J., Polu, K. R., Moller, C. C., Kenlan, P., Altintas, M. M., Wei, C., Faul, C., Herbert, S., Villegas, I., Avila-Casado, C., McGee, M., Sugimoto, H., Brown, D., Kalluri, R., Mundel, P., Smith, P. L., Clapham, D. E., Pollak, M. R.	Nat Genet	2005
15895247	Inhibition of TRPC5 channels by Ca2+-binding protein 1 in Xenopus oocytes.	Kinoshita-Kawada, M., Tang, J., Xiao, R., Kaneko, S., Foskett, J. K., Zhu, M. X.	Pflugers Arch	2005
15894168	Tyrosine phosphatase PTP1B interacts with TRPV6 in vivo and plays a role in TRPV6-mediated calcium influx in HEK293 cells.	Sternfeld, L., Krause, E., Schmid, A., Anderie, I., Latas, A., Al-Shaldi, H., Kohl, A., Evers, K., Hofer, H. W., Schulz, I.	Cell Signal	2005
15883036	Identification of a protein that interacts with the vanilloid receptor.	Lee, S. Y.	Biochem Biophys Res Commun	2005
15843396	Alpha-actinin associates with polycystin-2 and regulates its channel activity.	Li, Q., Montalbetti, N., Shen, P. Y., Dai, X. Q., Cheeseman, C. I., Karpinski, E., Wu, G., Cantiello, H. F., Chen, X. Z.	Hum Mol Genet	2005
15834157	Molecular analysis of a store-operated and 2-acetyl-sn-glycerol-sensitive non-selective cation channel. Heteromeric assembly of TRPC1-TRPC3.	Liu, X., Bandyopadhyay, B. C., Singh, B. B., Groschner, K., Ambudkar, I. S.	J Biol Chem	2005
15758179	Canonical transient receptor potential 1 plays a role in basic fibroblast growth factor (bFGF)/FGF receptor-1-induced Ca2+ entry and embryonic rat neural stem cell proliferation.	Fiorio Pla, A., Maric, D., Brazer, S. C., Giacobini, P., Liu, X., Chang, Y. H., Ambudkar, I. S., Barker, J. L.	J Neurosci	2005
15757897	MxA, a member of the dynamin superfamily, interacts with the ankyrin-like repeat domain of TRPC.	Lussier, M. P., Cayouette, S., Lepage, P. K., Bernier, C. L., Francoeur, N., St-Hilaire, M., Pinard, M., Boulay, G.	J Biol Chem	2005
15744307	Phospholipase Cgamma1 controls surface expression of TRPC3 through an intermolecular PH domain.	van Rossum, D. B., Patterson, R. L., Sharma, S., Barrow, R. K., Kornberg, M., Gill, D. L., Snyder, S. H.	Nature	2005
15713749	Homo- and heteromeric assembly of TRPV channel subunits.	Hellwig, N., Albrecht, N., Harteneck, C., Schultz, G., Schaefer, M.	J Cell Sci	2005
15692563	Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation.	Kottgen, M., Benzing, T., Simmen, T., Tauber, R., Buchholz, B., Feliciangeli, S., Huber, T. B., Schermer, B., Kramer-Zucker, A., Hopker, K., Simmen, K. C., Tschucke, C. C., Sandford, R., Kim, E., Thomas, G., Walz, G.	EMBO J	2005
15665527	Requirement of PDZ domains for the stimulation of the epithelial Ca2+ channel TRPV5 by the NHE regulating factor NHERF2 and the serum and glucocorticoid inducible kinase SGK1.	Palmada, M., Poppendieck, S., Embark, H. M., van de Graaf, S. F., Boehmer, C., Bindels, R. J., Lang, F.	Cell Physiol Biochem	2005
15654973	Phospholipase cgamma1 is required for activation of store-operated channels in human keratinocytes.	Tu, C. L., Chang, W., Bikle, D. D.	J Invest Dermatol	2005
15623527	Apical localization of a functional TRPC3/TRPC6-Ca2+-signaling complex in polarized epithelial cells. Role in apical Ca2+ influx.	Bandyopadhyay, B. C., Swaim, W. D., Liu, X., Redman, R. S., Patterson, R. L., Ambudkar, I. S.	J Biol Chem	2005
15590898	Expression of TRPC4 channel protein that interacts with NHERF-2 in rat descending vasa recta.	Lee-Kwon, W., Wade, J. B., Zhang, Z., Pallone, T. L., Weinman, E. J.	Am J Physiol Cell Physiol	2005
15590641	Regulation of the Ca2+ sensitivity of the nonselective cation channel TRPM4.	Nilius, B., Prenen, J., Tang, J., Wang, C., Owsianik, G., Janssens, A., Voets, T., Zhu, M. X.	J Biol Chem	2005
15569253	Identification and characterization of a Ca2+ -sensitive interaction of the vanilloid receptor TRPV1 with tubulin.	Goswami, C., Dreger, M., Jahnel, R., Bogen, O., Gillen, C., Hucho, F.	J Neurochem	2004
15548533	Genomic organization and functional analysis of murine PKD2L1.	Murakami, M., Ohba, T., Xu, F., Shida, S., Satoh, E., Ono, K., Miyoshi, I., Watanabe, H., Ito, H., Iijima, T.	J Biol Chem	2005
15547947	Formation of a physiological complex between TRPV2 and RGA protein promotes cell surface expression of TRPV2.	Stokes, A. J., Wakano, C., Del Carmen, K. A., Koblan-Huberson, M., Turner, H.	J Cell Biochem	2005
15540229	Canonical transient receptor potential channel 4 (TRPC4) co-localizes with the scaffolding protein ZO-1 in human fetal astrocytes in culture.	Song, X., Zhao, Y., Narcisse, L., Duffy, H., Kress, Y., Lee, S., Brosnan, C. F.	Glia	2005
15537648	Orexin-A-induced Ca2+ entry: evidence for involvement of trpc channels and protein kinase C regulation.	Larsson, K. P., Peltonen, H. M., Bart, G., Louhivuori, L. M., Penttonen, A., Antikainen, M., Kukkonen, J. P., Akerman, K. E.	J Biol Chem	2005
15485879	Phosphorylation of annexin I by TRPM7 channel-kinase.	Dorovkov, M. V., Ryazanov, A. G.	J Biol Chem	2004
15471852	Interaction between protein kinase Cmu and the vanilloid receptor type 1.	Wang, Y., Kedei, N., Wang, M., Wang, Q. J., Huppler, A. R., Toth, A., Tran, R., Blumberg, P. M.	J Biol Chem	2004
15385169	Enkurin is a novel calmodulin and TRPC channel binding protein in sperm.	Sutton, K. A., Jungnickel, M. K., Wang, Y., Cullen, K., Lambert, S., Florman, H. M.	Dev Biol	2004
15337773	Pericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assembly.	Jurczyk, A., Gromley, A., Redick, S., San Agustin, J., Witman, G., Pazour, G. J., Peters, D. J., Doxsey, S.	J Cell Biol	2004
15329338	Erythropoietin-modulated calcium influx through TRPC2 is mediated by phospholipase Cgamma and IP3R.	Tong, Q., Chu, X., Cheung, J. Y., Conrad, K., Stahl, R., Barber, D. L., Mignery, G., Miller, B. A.	Am J Physiol Cell Physiol	2004
15327778	VAMP2-dependent exocytosis regulates plasma membrane insertion of TRPC3 channels and contributes to agonist-stimulated Ca2+ influx.	Singh, B. B., Lockwich, T. P., Bandyopadhyay, B. C., Liu, X., Bollimuntha, S., Brazer, S. C., Combs, C., Das, S., Leenders, A. G., Sheng, Z. H., Knepper, M. A., Ambudkar, S. V., Ambudkar, I. S.	Mol Cell	2004
15302852	Junctate is a key element in calcium entry induced by activation of InsP3 receptors and/or calcium store depletion.	Treves, S., Franzini-Armstrong, C., Moccagatta, L., Arnoult, C., Grasso, C., Schrum, A., Ducreux, S., Zhu, M. X., Mikoshiba, K., Girard, T., Smida-Rezgui, S., Ronjat, M., Zorzato, F.	J Cell Biol	2004
15249591	A TRPV2-PKA signaling module for transduction of physical stimuli in mast cells.	Stokes, A. J., Shimoda, L. M., Koblan-Huberson, M., Adra, C. N., Turner, H.	J Exp Med	2004
15199065	Association of immunophilins with mammalian TRPC channels.	Sinkins, W. G., Goel, M., Estacion, M., Schilling, W. P.	J Biol Chem	2004
15194699	PIGEA-14, a novel coiled-coil protein affecting the intracellular distribution of polycystin-2.	Hidaka, S., Konecke, V., Osten, L., Witzgall, R.	J Biol Chem	2004
15188402	Proteins associated with type II bone morphogenetic protein receptor (BMPR-II) and identified by two-dimensional gel electrophoresis and mass spectrometry.	Hassel, S., Eichner, A., Yakymovych, M., Hellman, U., Knaus, P., Souchelnytskyi, S.	Proteomics	2004
15123714	PKD2 interacts and co-localizes with mDia1 to mitotic spindles of dividing cells: role of mDia1 IN PKD2 localization to mitotic spindles.	Rundle, D. R., Gorbsky, G., Tsiokas, L.	J Biol Chem	2004
15123711	Regulation of the mouse epithelial Ca2(+) channel TRPV6 by the Ca(2+)-sensor calmodulin.	Lambers, T. T., Weidema, A. F., Nilius, B., Hoenderop, J. G., Bindels, R. J.	J Biol Chem	2004
15121806	A role for SNAP-25 but not VAMPs in store-mediated Ca2+ entry in human platelets.	Redondo, P. C., Harper, A. G., Salido, G. M., Pariente, J. A., Sage, S. O., Rosado, J. A.	J Physiol	2004
15104175	TRPC channel interactions with calmodulin and IP3 receptors.	Zhu, M. X., Tang, J.	Novartis Found Symp	2004
15100231	80K-H as a new Ca2+ sensor regulating the activity of the epithelial Ca2+ channel transient receptor potential cation channel V5 (TRPV5).	Gkika, D., Mahieu, F., Nilius, B., Hoenderop, J. G., Bindels, R. J.	J Biol Chem	2004
15084474	Modulation of TRPV1 by nonreceptor tyrosine kinase, c-Src kinase.	Jin, X., Morsy, N., Winston, J., Pasricha, P. J., Garrett, K., Akbarali, H. I.	Am J Physiol Cell Physiol	2004
15066994	Regulated exocytosis contributes to protein kinase C potentiation of vanilloid receptor activity.	Morenilla-Palao, C., Planells-Cases, R., Garcia-Sanz, N., Ferrer-Montiel, A.	J Biol Chem	2004
15060061	The N-terminal extracellular domain is required for polycystin-1-dependent channel activity.	Babich, V., Zeng, W. Z., Yeh, B. I., Ibraghimov-Beskrovnaya, O., Cai, Y., Somlo, S., Huang, C. L.	J Biol Chem	2004
14991772	RGA protein associates with a TRPV ion channel during biosynthesis and trafficking.	Barnhill, J. C., Stokes, A. J., Koblan-Huberson, M., Shimoda, L. M., Muraguchi, A., Adra, C. N., Turner, H.	J Cell Biochem	2004
14983059	Regulation of canonical transient receptor potential isoform 3 (TRPC3) channel by protein kinase G.	Kwan, H. Y., Huang, Y., Yao, X.	Proc Natl Acad Sci U S A	2004
14976260	Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia.	Chubanov, V., Waldegger, S., Mederos y Schnitzler, M., Vitzthum, H., Sassen, M. C., Seyberth, H. W., Konrad, M., Gudermann, T.	Proc Natl Acad Sci U S A	2004
14761972	Regulation of TRPC6 channel activity by tyrosine phosphorylation.	Hisatsune, C., Kuroda, Y., Nakamura, K., Inoue, T., Nakamura, T., Michikawa, T., Mizutani, A., Mikoshiba, K.	J Biol Chem	2004
14736881	Ca(2+) signaling by TRPC3 involves Na(+) entry and local coupling to the Na(+)/Ca(2+) exchanger.	Rosker, C., Graziani, A., Lukas, M., Eder, P., Zhu, M. X., Romanin, C., Groschner, K.	J Biol Chem	2004
14699131	Interaction of TRPC2 and TRPC6 in erythropoietin modulation of calcium influx.	Chu, X., Tong, Q., Cheung, J. Y., Wozney, J., Conrad, K., Mazack, V., Zhang, W., Stahl, R., Barber, D. L., Miller, B. A.	J Biol Chem	2004
14699077	Ca2+/calmodulin modulates TRPV1 activation by capsaicin.	Rosenbaum, T., Gordon-Shaag, A., Munari, M., Gordon, S. E.	J Gen Physiol	2004
14614461	Activation of the TRPC1 cation channel by metabotropic glutamate receptor mGluR1.	Kim, S. J., Kim, Y. S., Yuan, J. P., Petralia, R. S., Worley, P. F., Linden, D. J.	Nature	2003
14551243	Cholesterol depletion impairs vascular reactivity to endothelin-1 by reducing store-operated Ca2+ entry dependent on TRPC1.	Bergdahl, A., Gomez, M. F., Dreja, K., Xu, S. Z., Adner, M., Beech, D. J., Broman, J., Hellstrand, P., Sward, K.	Circ Res	2003
14530267	Inhibitor of myogenic family, a novel suppressor of store-operated currents through an interaction with TRPC1.	Ma, R., Rundle, D., Jacks, J., Koch, M., Downs, T., Tsiokas, L.	J Biol Chem	2003
14523239	Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1).	Bhave, G., Hu, H. J., Glauner, K. S., Zhu, W., Wang, H., Brasier, D. J., Oxford, G. S., Gereau, R. W. 4th	Proc Natl Acad Sci U S A	2003
14517216	Microtubule-associated [corrected] protein 7 increases the membrane expression of transient receptor potential vanilloid 4 (TRPV4).	Suzuki, M., Hirao, A., Mizuno, A.	J Biol Chem	2003
14505576	Homer binds TRPC family channels and is required for gating of TRPC1 by IP3 receptors.	Yuan, J. P., Kiselyov, K., Shin, D. M., Chen, J., Shcheynikov, N., Kang, S. H., Dehoff, M. H., Schwarz, M. K., Seeburg, P. H., Muallem, S., Worley, P. F.	Cell	2003
12970180	Amplification of receptor signalling by Ca2+ entry-mediated translocation and activation of PLCgamma2 in B lymphocytes.	Nishida, M., Sugimoto, K., Hara, Y., Mori, E., Morii, T., Kurosaki, T., Mori, Y.	EMBO J	2003
12937304	Analysis of the polycystins in aortic vascular smooth muscle cells.	Qian, Q., Li, M., Cai, Y., Ward, C. J., Somlo, S., Harris, P. C., Torres, V. E.	J Am Soc Nephrol	2003
12858178	TRPC5 is a regulator of hippocampal neurite length and growth cone morphology.	Greka, A., Navarro, B., Oancea, E., Duggan, A., Clapham, D. E.	Nat Neurosci	2003
12857742	Formation of novel TRPC channels by complex subunit interactions in embryonic brain.	Strubing, C., Krapivinsky, G., Krapivinsky, L., Clapham, D. E.	J Biol Chem	2003
12840011	Polycystin-1 distribution is modulated by polycystin-2 expression in mammalian cells.	Grimm, D. H., Cai, Y., Chauvet, V., Rajendran, V., Zeltner, R., Geng, L., Avner, E. D., Sweeney, W., Somlo, S., Caplan, M. J.	J Biol Chem	2003
12809519	Troponin I binds polycystin-L and inhibits its calcium-induced channel activation.	Li, Q., Liu, Y., Shen, P. Y., Dai, X. Q., Wang, S., Smillie, L. B., Sandford, R., Chen, X. Z.	Biochemistry	2003
12808128	Structural determinant of TRPV1 desensitization interacts with calmodulin.	Numazaki, M., Tominaga, T., Takeuchi, K., Murayama, N., Toyooka, H., Tominaga, M.	Proc Natl Acad Sci U S A	2003
12766172	RhoA interaction with inositol 1,4,5-trisphosphate receptor and transient receptor potential channel-1 regulates Ca2+ entry. Role in signaling increased endothelial permeability.	Mehta, D., Ahmmed, G. U., Paria, B. C., Holinstat, M., Voyno-Yasenetskaya, T., Tiruppathi, C., Minshall, R. D., Malik, A. B.	J Biol Chem	2003
12765696	The TRPV6 gene, cDNA and protein.	Hirnet, D., Olausson, J., Fecher-Trost, C., Bodding, M., Nastainczyk, W., Wissenbach, U., Flockerzi, V., Freichel, M.	Cell Calcium	2003
12732636	Caveolin-1 contributes to assembly of store-operated Ca2+ influx channels by regulating plasma membrane localization of TRPC1.	Brazer, S. C., Singh, B. B., Liu, X., Swaim, W., Ambudkar, I. S.	J Biol Chem	2003
12724311	Ca2+-dependent potentiation of the nonselective cation channel TRPV4 is mediated by a C-terminal calmodulin binding site.	Strotmann, R., Schultz, G., Plant, T. D.	J Biol Chem	2003
12660155	Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex.	van de Graaf, S. F., Hoenderop, J. G., Gkika, D., Lamers, D., Prenen, J., Rescher, U., Gerke, V., Staub, O., Nilius, B., Bindels, R. J.	EMBO J	2003
12601176	The mouse C-type transient receptor potential 2 (TRPC2) channel: alternative splicing and calmodulin binding to its N terminus.	Yildirim, E., Dietrich, A., Birnbaumer, L.	Proc Natl Acad Sci U S A	2003
12574114	Homo- and heterotetrameric architecture of the epithelial Ca2+ channels TRPV5 and TRPV6.	Hoenderop, J. G., Voets, T., Hoefs, S., Weidema, F., Prenen, J., Nilius, B., Bindels, R. J.	EMBO J	2003
12538589	Regulation of a transient receptor potential (TRP) channel by tyrosine phosphorylation. SRC family kinase-dependent tyrosine phosphorylation of TRPV4 on TYR-253 mediates its response to hypotonic stress.	Xu, H., Zhao, H., Tian, W., Yoshida, K., Roullet, J. B., Cohen, D. M.	J Biol Chem	2003
12527301	Polycystin-2 associates with tropomyosin-1, an actin microfilament component.	Li, Q., Dai, Y., Guo, L., Liu, Y., Hao, C., Wu, G., Basora, N., Michalak, M., Chen, X. Z.	J Mol Biol	2003
12525172	Polycystin-2 interacts with troponin I, an angiogenesis inhibitor.	Li, Q., Shen, P. Y., Wu, G., Chen, X. Z.	Biochemistry	2003
12472899	Type-specific inositol 1,4,5-trisphosphate receptor localization in the vomeronasal organ and its interaction with a transient receptor potential channel, TRPC2.	Brann, J. H., Dennis, J. C., Morrison, E. E., Fadool, D. A.	J Neurochem	2002
12437926	Phospholipase C-gamma is required for agonist-induced Ca2+ entry.	Patterson, R. L., van Rossum, D. B., Ford, D. L., Hurt, K. J., Bae, S. S., Suh, P. G., Kurosaki, T., Snyder, S. H., Gill, D. L.	Cell	2002
12379180	Ca(2+)-calmodulin regulates receptor-operated Ca(2+) entry activity of TRPC6 in HEK-293 cells.	Boulay, G.	Cell Calcium	2002
12377790	Selective association of TRPC channel subunits in rat brain synaptosomes.	Goel, M., Sinkins, W. G., Schilling, W. P.	J Biol Chem	2002
12196544	Endogenously expressed Trp1 is involved in store-mediated Ca2+ entry by conformational coupling in human platelets.	Rosado, J. A., Brownlow, S. L., Sage, S. O.	J Biol Chem	2002
12194871	cAMP-dependent protein kinase regulates desensitization of the capsaicin receptor (VR1) by direct phosphorylation.	Bhave, G., Zhu, W., Wang, H., Brasier, D. J., Oxford, G. S., Gereau, R. W. 4th	Neuron	2002
12167663	Erythropoietin modulates calcium influx through TRPC2.	Chu, X., Cheung, J. Y., Barber, D. L., Birnbaumer, L., Rothblum, L. I., Conrad, K., Abrasonis, V., Chan, Y. M., Stahl, R., Carey, D. J., Miller, B. A.	J Biol Chem	2002
12154080	The PDZ-interacting domain of TRPC4 controls its localization and surface expression in HEK293 cells.	Mery, L., Strauss, B., Dufour, J. F., Krause, K. H., Hoth, M.	J Cell Sci	2002
12077606	TRPV3 is a temperature-sensitive vanilloid receptor-like protein.	Smith, G. D., Gunthorpe, M. J., Kelsell, R. E., Hayes, P. D., Reilly, P., Facer, P., Wright, J. E., Jerman, J. C., Walhin, J. P., Ooi, L., Egerton, J., Charles, K. J., Smart, D., Randall, A. D., Anand, P., Davis, J. B.	Nature	2002
12032305	Subunit composition of mammalian transient receptor potential channels in living cells.	Hofmann, T., Schaefer, M., Schultz, G., Gudermann, T.	Proc Natl Acad Sci U S A	2002
11983166	Calmodulin regulates Ca(2+)-dependent feedback inhibition of store-operated Ca(2+) influx by interaction with a site in the C terminus of TrpC1.	Singh, B. B., Liu, X., Tang, J., Zhu, M. X., Ambudkar, I. S.	Mol Cell	2002
11941371	The TRPM7 channel is inactivated by PIP(2) hydrolysis.	Runnels, L. W., Yue, L., Clapham, D. E.	Nat Cell Biol	2002
11901144	Identification, characterization, and localization of a novel kidney polycystin-1-polycystin-2 complex.	Newby, L. J., Streets, A. J., Zhao, Y., Harris, P. C., Ward, C. J., Ong, A. C.	J Biol Chem	2002
11884385	Direct phosphorylation of capsaicin receptor VR1 by protein kinase Cepsilon and identification of two target serine residues.	Numazaki, M., Tominaga, T., Toyooka, H., Tominaga, M.	J Biol Chem	2002
11524429	Stabilization of cortical actin induces internalization of transient receptor potential 3 (Trp3)-associated caveolar Ca2+ signaling complex and loss of Ca2+ influx without disruption of Trp3-inositol trisphosphate receptor association.	Lockwich, T., Singh, B. B., Liu, X., Ambudkar, I. S.	J Biol Chem	2001
11418861	Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition.	Chuang, H. H., Prescott, E. D., Kong, H., Shields, S., Jordt, S. E., Basbaum, A. I., Chao, M. V., Julius, D.	Nature	2001
11336651	Activation of store-mediated calcium entry by secretion-like coupling between the inositol 1,4,5-trisphosphate receptor type II and human transient receptor potential (hTrp1) channels in human platelets.	Rosado, J. A., Sage, S. O.	Biochem J	2001
11311128	The transient receptor potential, TRP4, cation channel is a novel member of the family of calmodulin binding proteins.	Trost, C., Bergs, C., Himmerkus, N., Flockerzi, V.	Biochem J	2001
11301024	TRPC1 and TRPC5 form a novel cation channel in mammalian brain.	Strubing, C., Krapivinsky, G., Krapivinsky, L., Clapham, D. E.	Neuron	2001
11290752	Identification of common binding sites for calmodulin and inositol 1,4,5-trisphosphate receptors on the carboxyl termini of trp channels.	Tang, J., Lin, Y., Zhang, Z., Tikunova, S., Birnbaumer, L., Zhu, M. X.	J Biol Chem	2001
11248124	Competitive regulation of CaT-like-mediated Ca2+ entry by protein kinase C and calmodulin.	Niemeyer, B. A., Bergs, C., Wissenbach, U., Flockerzi, V., Trost, C.	Proc Natl Acad Sci U S A	2001
11248050	Activation of Trp3 by inositol 1,4,5-trisphosphate receptors through displacement of inhibitory calmodulin from a common binding domain.	Zhang, Z., Tang, J., Tikunova, S., Johnson, J. D., Chen, Z., Qin, N., Dietrich, A., Stefani, E., Birnbaumer, L., Zhu, M. X.	Proc Natl Acad Sci U S A	2001
11163362	Alternative splice variants of hTrp4 differentially interact with the C-terminal portion of the inositol 1,4,5-trisphosphate receptors.	Mery, L., Magnino, F., Schmidt, K., Krause, K. H., Dufour, J. F.	FEBS Lett	2001
11161216	TRP-PLIK, a bifunctional protein with kinase and ion channel activities.	Runnels, L. W., Yue, L., Clapham, D. E.	Science	2001
11140688	Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents.	Hanaoka, K., Qian, F., Boletta, A., Bhunia, A. K., Piontek, K., Tsiokas, L., Sukhatme, V. P., Guggino, W. B., Germino, G. G.	Nature	2000
10983988	Gating of store-operated channels by conformational coupling to ryanodine receptors.	Kiselyov, K. I., Shin, D. M., Wang, Y., Pessah, I. N., Allen, P. D., Muallem, S.	Mol Cell	2000
10980202	Association of mammalian trp4 and phospholipase C isozymes with a PDZ domain-containing protein, NHERF.	Tang, Y., Tang, J., Chen, Z., Trost, C., Flockerzi, V., Li, M., Ramesh, V., Zhu, M. X.	J Biol Chem	2000
10980191	Expression of truncated transient receptor potential protein 1alpha (Trp1alpha ): evidence that the Trp1 C terminus modulates store-operated Ca2+ entry.	Singh, B. B., Liu, X., Ambudkar, I. S.	J Biol Chem	2000
10970773	Coupling between inositol 1,4,5-trisphosphate receptors and human transient receptor potential channel 1 when intracellular Ca2+ stores are depleted.	Rosado, J. A., Sage, S. O.	Biochem J	2000
10913159	In vivo interaction of the adapter protein CD2-associated protein with the type 2 polycystic kidney disease protein, polycystin-2.	Lehtonen, S., Ora, A., Olkkonen, V. M., Geng, L., Zerial, M., Somlo, S., Lehtonen, E.	J Biol Chem	2000
10882720	Coassembly of Trp1 and Trp3 proteins generates diacylglycerol- and Ca2+-sensitive cation channels.	Lintschinger, B., Balzer-Geldsetzer, M., Baskaran, T., Graier, W. F., Romanin, C., Zhu, M. X., Groschner, K.	J Biol Chem	2000
10766822	Assembly of Trp1 in a signaling complex associated with caveolin-scaffolding lipid raft domains.	Lockwich, T. P., Liu, X., Singh, B. B., Jadlowiec, J., Weiland, S., Ambudkar, I. S.	J Biol Chem	2000
10760273	The polycystic kidney disease protein PKD2 interacts with Hax-1, a protein associated with the actin cytoskeleton.	Gallagher, A. R., Cedzich, A., Gretz, N., Somlo, S., Witzgall, R.	Proc Natl Acad Sci U S A	2000
10677043	Activation of a TRPC3-dependent cation current through the neurotrophin BDNF.	Li, H. S., Xu, X. Z., Montell, C.	Neuron	1999
10611319	Modulation of Ca(2+) entry by polypeptides of the inositol 1,4, 5-trisphosphate receptor (IP3R) that bind transient receptor potential (TRP): evidence for roles of TRP and IP3R in store depletion-activated Ca(2+) entry.	Boulay, G., Brown, D. M., Qin, N., Jiang, M., Dietrich, A., Zhu, M. X., Chen, Z., Birnbaumer, M., Mikoshiba, K., Birnbaumer, L.	Proc Natl Acad Sci U S A	1999
10518223	The N-terminal domain of the IP3 receptor gates store-operated hTrp3 channels.	Kiselyov, K., Mignery, G. A., Zhu, M. X., Muallem, S.	Mol Cell	1999
10097141	Specific association of the gene product of PKD2 with the TRPC1 channel.	Tsiokas, L., Arnould, T., Zhu, C., Kim, E., Walz, G., Sukhatme, V. P.	Proc Natl Acad Sci U S A	1999
9215637	Coassembly of TRP and TRPL produces a distinct store-operated conductance.	Xu, X. Z., Li, H. S., Guggino, W. B., Montell, C.	Cell	1997
9192675	Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2.	Tsiokas, L., Kim, E., Arnould, T., Sukhatme, V. P., Walz, G.	Proc Natl Acad Sci U S A	1997
9171830	PKD1 interacts with PKD2 through a probable coiled-coil domain.	Qian, F., Germino, F. J., Cai, Y., Zhang, X., Somlo, S., Germino, G. G.	Nat Genet	1997

TRPM2 mediates ischemic kidney injury and oxidant stress through RAC1.

External 2231691f894ba696de1310221b0a0dbbb31a7251e75115c265587c3d9d5f507c

Gao, G., Wang, W., Tadagavadi, R. K., Briley, N. E., Love, M. I., Miller, B. A., Reeves, W. B.

J Clin Invest

2014

25231975

Casein kinase-mediated phosphorylation of serine 839 is necessary for basolateral localization of the Ca(2)(+)-activated non-selective cation channel TRPM4.

Cerda, O., Caceres, M., Park, K. S., Leiva-Salcedo, E., Romero, A., Varela, D., Trimmer, J. S., Stutzin, A.

Pflugers Arch

2015

25172921

TRPV6 calcium channel translocates to the plasma membrane via Orai1-mediated mechanism and controls cancer cell survival.

Raphael, M., Lehen'kyi, V., Vandenberghe, M., Beck, B., Khalimonchyk, S., Vanden Abeele, F., Farsetti, L., Germain, E., Bokhobza, A., Mihalache, A., Gosset, P., Romanin, C., Clezardin, P., Skryma, R., Prevarskaya, N.

Proc Natl Acad Sci U S A

2014

25139746

Nitric oxide and protein kinase G act on TRPC1 to inhibit 11,12-EET-induced vascular relaxation.

Zhang, P., Ma, Y., Wang, Y., Ma, X., Huang, Y., Li, R. A., Wan, S., Yao, X.

Cardiovasc Res

2014

25130899

Cellular Zinc Levels Are Modulated by TRPML1-TMEM163 Interaction.

Cuajungco, M. P., Basilio, L. C., Silva, J., Hart, T., Tringali, J., Chen, C. C., Biel, M., Grimm, C.

Traffic

2014

25123313

Unique interweaved microtubule scaffold mediates osmosensory transduction via physical interaction with TRPV1.

Prager-Khoutorsky, M., Khoutorsky, A., Bourque, C. W.

Neuron

2014

25114176

TRPV4, TRPC1, and TRPP2 assemble to form a flow-sensitive heteromeric channel.

Du, J., Ma, X., Shen, B., Huang, Y., Birnbaumer, L., Yao, X.

FASEB J

2014

25049082

The phosphatidylinositol(4,5)bisphosphate-binding sequence of transient receptor potential channel canonical 4alpha is critical for its contribution to cardiomyocyte hypertrophy.

Cooley, N., Grubb, D. R., Luo, J., Woodcock, E. A.

Mol Pharmacol

2014

25047048

Depletion of 14-3-3gamma reduces the surface expression of Transient Receptor Potential Melastatin 4b (TRPM4b) Channels and attenuates TRPM4b-mediated glutamate-induced neuronal cell death.

Cho, C. H., Kim, E., Lee, Y. S., Yarishkin, O., Yoo, J. C., Park, J. Y., Hong, S. G., Hwang, E. M.

Mol Brain

2014

25014183

Functional and biochemical interaction between PPARalpha receptors and TRPV1 channels: Potential role in PPARalpha agonists-mediated analgesia.

Ambrosino, P., Soldovieri, M. V., De Maria, M., Russo, C., Taglialatela, M.

Pharmacol Res

2014

25013939

Helminth induced suppression of macrophage activation is correlated with inhibition of calcium channel activity.

Chauhan, A., Sun, Y., Pani, B., Quenumzangbe, F., Sharma, J., Singh, B. B., Mishra, B. B.

PLoS One

2014

25005230

AKAP150-dependent cooperative TRPV4 channel gating is central to endothelium-dependent vasodilation and is disrupted in hypertension.

Sonkusare, S. K., Dalsgaard, T., Bonev, A. D., Hill-Eubanks, D. C., Kotlikoff, M. I., Scott, J. D., Santana, L. F., Nelson, M. T.

Sci Signal

2014

24939696

Following OGD/R, annexin 1 nuclear translocation and subsequent induction of apoptosis in neurons are assisted by myosin IIA in a TRPM7 kinase-dependent manner.

Zhao, Y., Wang, J., Jiang, H., Yu, Z., Li, X., Shi, J.

Mol Neurobiol

2015

24920628

The basal thermal sensitivity of the TRPV1 ion channel is determined by PKCbetaII.

Li, L., Hasan, R., Zhang, X.

J Neurosci

2014

24890824

Transient receptor potential vanilloid 1 activation by dietary capsaicin promotes urinary sodium excretion by inhibiting epithelial sodium channel alpha subunit-mediated sodium reabsorption.

Li, L., Wang, F., Wei, X., Liang, Y., Cui, Y., Gao, F., Zhong, J., Pu, Y., Zhao, Y., Yan, Z., Arendshorst, W. J., Nilius, B., Chen, J., Liu, D., Zhu, Z.

Hypertension

2014

24778429

Local control of TRPV4 channels by AKAP150-targeted PKC in arterial smooth muscle.

Mercado, J., Baylie, R., Navedo, M. F., Yuan, C., Scott, J. D., Nelson, M. T., Brayden, J. E., Santana, L. F.

J Gen Physiol

2014

24740790

Phosphodiesterase 5 inhibition ameliorates angiontensin II-induced podocyte dysmotility via the protein kinase G-mediated downregulation of TRPC6 activity.

Hall, G., Rowell, J., Farinelli, F., Gbadegesin, R. A., Lavin, P., Wu, G., Homstad, A., Malone, A., Lindsey, T., Jiang, R., Spurney, R., Tomaselli, G. F., Kass, D. A., Winn, M. P.

Am J Physiol Renal Physiol

2014

24704446

Reciprocal positive regulation between TRPV6 and NUMB in PTEN-deficient prostate cancer cells.

Kim, S. Y., Hong, C., Wie, J., Kim, E., Kim, B. J., Ha, K., Cho, N. H., Kim, I. G., Jeon, J. H., So, I.

Biochem Biophys Res Commun

2014

24695785

Activation of mu opioid receptors sensitizes transient receptor potential vanilloid type 1 (TRPV1) via beta-arrestin-2-mediated cross-talk.

Rowan, M. P., Bierbower, S. M., Eskander, M. A., Szteyn, K., Por, E. D., Gomez, R., Veldhuis, N., Bunnett, N. W., Jeske, N. A.

PLoS One

2014

24630989

Caspase-11 controls interleukin-1beta release through degradation of TRPC1.

Py, B. F., Jin, M., Desai, B. N., Penumaka, A., Zhu, H., Kober, M., Dietrich, A., Lipinski, M. M., Henry, T., Clapham, D. E., Yuan, J.

Cell Rep

2014

24613381

Heteromeric TRPC3 with TRPC1 formed via its ankyrin repeats regulates the resting cytosolic Ca2+ levels in skeletal muscle.

Woo, J. S., Lee, K. J., Huang, M., Cho, C. H., Lee, E. H.

Biochem Biophys Res Commun

2014

24596097

A disease-causing mutation illuminates the protein membrane topology of the kidney-expressed prohibitin homology (PHB) domain protein podocin.

Schurek, E. M., Volker, L. A., Tax, J., Lamkemeyer, T., Rinschen, M. M., Ungrue, D., Kratz, J. E. 3rd, Sirianant, L., Kunzelmann, K., Chalfie, M., Schermer, B., Benzing, T., Hohne, M.

J Biol Chem

2014

24563462

Trans-activation response (TAR) RNA-binding protein 2 is a novel modulator of transient receptor potential canonical 4 (TRPC4) protein.

Zimmermann, J., Latta, L., Beck, A., Leidinger, P., Fecher-Trost, C., Schlenstedt, G., Meese, E., Wissenbach, U., Flockerzi, V.

J Biol Chem

2014

24509911

Modulation of water efflux through functional interaction between TRPV4 and TMEM16A/anoctamin 1.

Takayama, Y., Shibasaki, K., Suzuki, Y., Yamanaka, A., Tominaga, M.

FASEB J

2014

24464579

Molecular determinants mediating gating of Transient Receptor Potential Canonical (TRPC) channels by stromal interaction molecule 1 (STIM1).

Lee, K. P., Choi, S., Hong, J. H., Ahuja, M., Graham, S., Ma, R., So, I., Shin, D. M., Muallem, S., Yuan, J. P.

J Biol Chem

2014

24459142

Polycystin-1 negatively regulates Polycystin-2 expression via the aggresome/autophagosome pathway.

Cebotaru, V., Cebotaru, L., Kim, H., Chiaravalli, M., Boletta, A., Qian, F., Guggino, W. B.

J Biol Chem

2014

24391909

Role of endogenous ENaC and TRP channels in the myogenic response of rat posterior cerebral arteries.

Kim, E. C., Choi, S. K., Lim, M., Yeon, S. I., Lee, Y. H.

PLoS One

2013

24385424

The TRPM6 kinase domain determines the Mg.ATP sensitivity of TRPM7/M6 heteromeric ion channels.

Zhang, Z., Yu, H., Huang, J., Faouzi, M., Schmitz, C., Penner, R., Fleig, A.

J Biol Chem

2014

24337049

Cooperative interaction of trp melastatin channel transient receptor potential (TRPM2) with its splice variant TRPM2 short variant is essential for endothelial cell apoptosis.

Hecquet, C. M., Zhang, M., Mittal, M., Vogel, S. M., Di, A., Gao, X., Bonini, M. G., Malik, A. B.

Circ Res

2014

24269818

The Ca2+ channel TRPML3 specifically interacts with the mammalian ATG8 homologue GATE16 to regulate autophagy.

Choi, S., Kim, H. J.

Biochem Biophys Res Commun

2014

24269608

The TRPM8 channel forms a complex with the 5-HT1B receptor and phospholipase D that amplifies its reversal of pain hypersensitivity.

Vinuela-Fernandez, I., Sun, L., Jerina, H., Curtis, J., Allchorne, A., Gooding, H., Rosie, R., Holland, P., Tas, B., Mitchell, R., Fleetwood-Walker, S.

Neuropharmacology

2014

24157948

Piezo1-dependent stretch-activated channels are inhibited by Polycystin-2 in renal tubular epithelial cells.

Peyronnet, R., Martins, J. R., Duprat, F., Demolombe, S., Arhatte, M., Jodar, M., Tauc, M., Duranton, C., Paulais, M., Teulon, J., Honore, E., Patel, A.

EMBO Rep

2013

24147119

TRPV1 channels are functionally coupled with BK(mSlo1) channels in rat dorsal root ganglion (DRG) neurons.

Wu, Y., Liu, Y., Hou, P., Yan, Z., Kong, W., Liu, B., Li, X., Yao, J., Zhang, Y., Qin, F., Ding, J.

PLoS One

2013

24146259

Expression and localization of TRPC proteins in rat ventricular myocytes at various developmental stages.

Jiang, Y., Huang, H., Liu, P., Wei, H., Zhao, H., Feng, Y., Wang, W., Niu, W.

Cell Tissue Res

2014

24114537

Orphan receptor GPR179 forms macromolecular complexes with components of metabotropic signaling cascade in retina ON-bipolar neurons.

Orlandi, C., Cao, Y., Martemyanov, K. A.

Invest Ophthalmol Vis Sci

2013

24114458

Inhibition of the Sur1-Trpm4 channel reduces neuroinflammation and cognitive impairment in subarachnoid hemorrhage.

Tosun, C., Kurland, D. B., Mehta, R., Castellani, R. J., deJong, J. L., Kwon, M. S., Woo, S. K., Gerzanich, V., Simard, J. M.

Stroke

2013

24036102

Identification of voltage-gated K(+) channel beta 2 (Kvbeta2) subunit as a novel interaction partner of the pain transducer Transient Receptor Potential Vanilloid 1 channel (TRPV1).

Bavassano, C., Marvaldi, L., Langeslag, M., Sarg, B., Lindner, H., Klimaschewski, L., Kress, M., Ferrer-Montiel, A., Knaus, H. G.

Biochim Biophys Acta

2013

24022404

Myristoylated alanine-rich C kinase substrate coordinates native TRPC1 channel activation by phosphatidylinositol 4,5-bisphosphate and protein kinase C in vascular smooth muscle.

Shi, J., Birnbaumer, L., Large, W. A., Albert, A. P.

FASEB J

2014

24011658

Activation of TRPC4beta by Galphai subunit increases Ca2+ selectivity and controls neurite morphogenesis in cultured hippocampal neuron.

Jeon, J. P., Roh, S. E., Wie, J., Kim, J., Kim, H., Lee, K. P., Yang, D., Jeon, J. H., Cho, N. H., Kim, I. G., Kang, D. E., Kim, H. J., So, I.

Cell Calcium

2013

23994313

Transient receptor potential ankyrin-1 (TRPA1) modulates store-operated Ca(2+) entry by regulation of STIM1-Orai1 association.

Albarran, L., Lopez, J. J., Dionisio, N., Smani, T., Salido, G. M., Rosado, J. A.

Biochim Biophys Acta

2013

23977387

TRPP2 and TRPV4 form an EGF-activated calcium permeable channel at the apical membrane of renal collecting duct cells.

Zhang, Z. R., Chu, W. F., Song, B., Gooz, M., Zhang, J. N., Yu, C. J., Jiang, S., Baldys, A., Gooz, P., Steele, S., Owsianik, G., Nilius, B., Komlosi, P., Bell, P. D.

PLoS One

2013

23911290

Opiates modulate thermosensation by internalizing cold receptor TRPM8.

Shapovalov, G., Gkika, D., Devilliers, M., Kondratskyi, A., Gordienko, D., Busserolles, J., Bokhobza, A., Eschalier, A., Skryma, R., Prevarskaya, N.

Cell Rep

2013

23770672

A TRPC1 protein-dependent pathway regulates osteoclast formation and function.

Ong, E. C., Nesin, V., Long, C. L., Bai, C. X., Guz, J. L., Ivanov, I. P., Abramowitz, J., Birnbaumer, L., Humphrey, M. B., Tsiokas, L.

J Biol Chem

2013

23747339

Post-translational loss of renal TRPV5 calcium channel expression, Ca(2+) wasting, and bone loss in experimental colitis.

Radhakrishnan, V. M., Ramalingam, R., Larmonier, C. B., Thurston, R. D., Laubitz, D., Midura-Kiela, M. T., McFadden, R. M., Kuro-O, M., Kiela, P. R., Ghishan, F. K.

Gastroenterology

2013

23699529

Mapping the binding site of TRPV1 on AKAP79: implications for inflammatory hyperalgesia.

Btesh, J., Fischer, M. J., Stott, K., McNaughton, P. A.

J Neurosci

2013

23690576

Phosphatidylinositol-4,5-biphosphate-dependent rearrangement of TRPV4 cytosolic tails enables channel activation by physiological stimuli.

Garcia-Elias, A., Mrkonjic, S., Pardo-Pastor, C., Inada, H., Hellmich, U. A., Rubio-Moscardo, F., Plata, C., Gaudet, R., Vicente, R., Valverde, M. A.

Proc Natl Acad Sci U S A

2013

23686296

Functional transient receptor potential canonical type 1 channels in human atrial myocytes.

Zhang, Y. H., Wu, H. J., Che, H., Sun, H. Y., Cheng, L. C., Li, X., Au, W. K., Tse, H. F., Li, G. R.

Pflugers Arch

2013

23671622

Characterization of the S100A1 protein binding site on TRPC6 C-terminus.

Bily, J., Grycova, L., Holendova, B., Jirku, M., Janouskova, H., Bousova, K., Teisinger, J.

PLoS One

2013

23645677

Gain-of-function mutations in transient receptor potential C6 (TRPC6) activate extracellular signal-regulated kinases 1/2 (ERK1/2).

Chiluiza, D., Krishna, S., Schumacher, V. A., Schlondorff, J.

J Biol Chem

2013

23616546

Disrupting sensitization of transient receptor potential vanilloid subtype 1 inhibits inflammatory hyperalgesia.

Fischer, M. J., Btesh, J., McNaughton, P. A.

J Neurosci

2013

23508958

Excitation and modulation of TRPA1, TRPV1, and TRPM8 channel-expressing sensory neurons by the pruritogen chloroquine.

Than, J. Y., Li, L., Hasan, R., Zhang, X.

J Biol Chem

2013

23469151

A novel ion channel formed by interaction of TRPML3 with TRPV5.

Guo, Z., Grimm, C., Becker, L., Ricci, A. J., Heller, S.

PLoS One

2013

23418601

Systematic screens for proteins that interact with the mucolipidosis type IV protein TRPML1.

Spooner, E., McLaughlin, B. M., Lepow, T., Durns, T. A., Randall, J., Upchurch, C., Miller, K., Campbell, E. M., Fares, H.

PLoS One

2013

23395841

The polybasic lysine-rich domain of plasma membrane-resident STIM1 is essential for the modulation of store-operated divalent cation entry by extracellular calcium.

Jardin, I., Dionisio, N., Frischauf, I., Berna-Erro, A., Woodard, G. E., Lopez, J. J., Salido, G. M., Rosado, J. A.

Cell Signal

2013

23390129

Hyperphosphorylation of polycystin-2 at a critical residue in disease reveals an essential role for polycystin-1-regulated dephosphorylation.

Streets, A. J., Wessely, O., Peters, D. J., Ong, A. C.

Hum Mol Genet

2013

23375350

Regulation of store-operated calcium entry by FK506-binding immunophilins.

Kadeba, P. I., Vasauskas, A. A., Chen, H., Wu, S., Scammell, J. G., Cioffi, D. L.

Cell Calcium

2013

23360390

Phosphorylation regulates TRPV1 association with beta-arrestin-2.

Por, E. D., Gomez, R., Akopian, A. N., Jeske, N. A.

Biochem J

2013

23345400

Occludin is required for TRPV1-modulated paracellular permeability in the submandibular gland.

Cong, X., Zhang, Y., Yang, N. Y., Li, J., Ding, C., Ding, Q. W., Su, Y. C., Mei, M., Guo, X. H., Wu, L. L., Yu, G. Y.

J Cell Sci

2013

23264624

Scaffolding by A-kinase anchoring protein enhances functional coupling between adenylyl cyclase and TRPV1 channel.

Efendiev, R., Bavencoffe, A., Hu, H., Zhu, M. X., Dessauer, C. W.

J Biol Chem

2013

23255597

The sulfonylurea receptor 1 (Sur1)-transient receptor potential melastatin 4 (Trpm4) channel.

Woo, S. K., Kwon, M. S., Ivanov, A., Gerzanich, V., Simard, J. M.

J Biol Chem

2013

23228564

FKBP52 is involved in the regulation of SOCE channels in the human platelets and MEG 01 cells.

Lopez, E., Berna-Erro, A., Salido, G. M., Rosado, J. A., Redondo, P. C.

Biochim Biophys Acta

2013

23212381

Molecular mechanism of the assembly of an acid-sensing receptor ion channel complex.

Yu, Y., Ulbrich, M. H., Li, M. H., Dobbins, S., Zhang, W. K., Tong, L., Isacoff, E. Y., Yang, J.

Nat Commun

2012

23171048

SNF8, a member of the ESCRT-II complex, interacts with TRPC6 and enhances its channel activity.

Carrasquillo, R., Tian, D., Krishna, S., Pollak, M. R., Greka, A., Schlondorff, J.

BMC Cell Biol

2012

23159249

Recurrent de novo mutations in PACS1 cause defective cranial-neural-crest migration and define a recognizable intellectual-disability syndrome.

Schuurs-Hoeijmakers, J. H., Oh, E. C., Vissers, L. E., Swinkels, M. E., Gilissen, C., Willemsen, M. A., Holvoet, M., Steehouwer, M., Veltman, J. A., de Vries, B. B., van Bokhoven, H., de Brouwer, A. P., Katsanis, N., Devriendt, K., Brunner, H. G.

Am J Hum Genet

2012

23142606

Cannabinoid receptor 1 suppresses transient receptor potential vanilloid 1-induced inflammatory responses to corneal injury.

Yang, Y., Yang, H., Wang, Z., Varadaraj, K., Kumari, S. S., Mergler, S., Okada, Y., Saika, S., Kingsley, P. J., Marnett, L. J., Reinach, P. S.

Cell Signal

2013

23140583

Regulation of calcium influx and signaling pathway in cancer cells via TRPV6-Numb1 interaction.

Kim, S. Y., Yang, D., Myeong, J., Ha, K., Kim, S. H., Park, E. J., Kim, I. G., Cho, N. H., Lee, K. P., Jeon, J. H., So, I.

Cell Calcium

2013

23119017

Integrative binding sites within intracellular termini of TRPV1 receptor.

Grycova, L., Holendova, B., Bumba, L., Bily, J., Jirku, M., Lansky, Z., Teisinger, J.

PLoS One

2012

23109716

Distinct properties of Ca2+-calmodulin binding to N- and C-terminal regulatory regions of the TRPV1 channel.

Lau, S. Y., Procko, E., Gaudet, R.

J Gen Physiol

2012

23077056

Cyclin-dependent kinase 5 controls TRPV1 membrane trafficking and the heat sensitivity of nociceptors through KIF13B.

Xing, B. M., Yang, Y. R., Du, J. X., Chen, H. J., Qi, C., Huang, Z. H., Zhang, Y., Wang, Y.

J Neurosci

2012

23068106

Different binding property of STIM1 and its novel splice variant STIM1L to Orai1, TRPC3, and TRPC6 channels.

Horinouchi, T., Higashi, T., Higa, T., Terada, K., Mai, Y., Aoyagi, H., Hatate, C., Nepal, P., Horiguchi, M., Harada, T., Miwa, S.

Biochem Biophys Res Commun

2012

23045459

An elevation in physical coupling of type 1 inositol 1,4,5-trisphosphate (IP3) receptors to transient receptor potential 3 (TRPC3) channels constricts mesenteric arteries in genetic hypertension.

Adebiyi, A., Thomas-Gatewood, C. M., Leo, M. D., Kidd, M. W., Neeb, Z. P., Jaggar, J. H.

Hypertension

2012

23034388

TRPC1 and Orai1 interact with STIM1 and mediate capacitative Ca(2+) entry caused by acute hypoxia in mouse pulmonary arterial smooth muscle cells.

Ng, L. C., O'Neill, K. G., French, D., Airey, J. A., Singer, C. A., Tian, H., Shen, X. M., Hume, J. R.

Am J Physiol Cell Physiol

2012

22952227

beta-Arrestin-2 desensitizes the transient receptor potential vanilloid 1 (TRPV1) channel.

Por, E. D., Bierbower, S. M., Berg, K. A., Gomez, R., Akopian, A. N., Wetsel, W. C., Jeske, N. A.

J Biol Chem

2012

22932896

Canonical transient receptor potential (TRPC) 1 acts as a negative regulator for vanilloid TRPV6-mediated Ca2+ influx.

Schindl, R., Fritsch, R., Jardin, I., Frischauf, I., Kahr, H., Muik, M., Riedl, M. C., Groschner, K., Romanin, C.

J Biol Chem

2012

22789851

Activation of NMDA receptors leads to phosphorylation of TRPV1 S800 by protein kinase C and A-Kinase anchoring protein 150 in rat trigeminal ganglia.

Lee, J., Chung, M. K., Ro, J. Y.

Biochem Biophys Res Commun

2012

22778254

Extracellular Ca(2+) sensing in salivary ductal cells.

Bandyopadhyay, B. C., Swaim, W. D., Sarkar, A., Liu, X., Ambudkar, I. S.

J Biol Chem

2012

22759789

Identification of Ser/Thr phosphorylation sites in the C2-domain of phospholipase C gamma2 (PLCgamma2) using TRPM7-kinase.

Deason-Towne, F., Perraud, A. L., Schmitz, C.

Cell Signal

2012

22750945

Direct inhibition of the cold-activated TRPM8 ion channel by Galphaq.

Zhang, X., Mak, S., Li, L., Parra, A., Denlinger, B., Belmonte, C., McNaughton, P. A.

Nat Cell Biol

2012

22640869

Capacitative and non-capacitative signaling complexes in human platelets.

Berna-Erro, A., Galan, C., Dionisio, N., Gomez, L. J., Salido, G. M., Rosado, J. A.

Biochim Biophys Acta

2012

22609428

Functional interactions between NMDA receptors and TRPV1 in trigeminal sensory neurons mediate mechanical hyperalgesia in the rat masseter muscle.

Lee, J., Saloman, J. L., Weiland, G., Auh, Q. S., Chung, M. K., Ro, J. Y.

Pain

2012

22592407

Polyamines regulate intestinal epithelial restitution through TRPC1-mediated Ca(2)+ signaling by differentially modulating STIM1 and STIM2.

Rao, J. N., Rathor, N., Zhuang, R., Zou, T., Liu, L., Xiao, L., Turner, D. J., Wang, J. Y.

Am J Physiol Cell Physiol

2012

22534489

Orai1 determines calcium selectivity of an endogenous TRPC heterotetramer channel.

Cioffi, D. L., Wu, S., Chen, H., Alexeyev, M., St Croix, C. M., Pitt, B. R., Uhlig, S., Stevens, T.

Circ Res

2012

22518003

Protein kinase G inhibits flow-induced Ca2+ entry into collecting duct cells.

Du, J., Wong, W. Y., Sun, L., Huang, Y., Yao, X.

J Am Soc Nephrol

2012

22506990

Homers regulate calcium entry and aggregation in human platelets: a role for Homers in the association between STIM1 and Orai1.

Jardin, I., Albarran, L., Bermejo, N., Salido, G. M., Rosado, J. A.

Biochem J

2012

22492541

Calcium/calmodulin-signaling supports TRPV4 activation in osteoclasts and regulates bone mass.

Masuyama, R., Mizuno, A., Komori, H., Kajiya, H., Uekawa, A., Kitaura, H., Okabe, K., Ohyama, K., Komori, T.

J Bone Miner Res

2012

22460725

The TRPM8 ion channel comprises direct Gq protein-activating capacity.

Klasen, K., Hollatz, D., Zielke, S., Gisselmann, G., Hatt, H., Wetzel, C. H.

Pflugers Arch

2012

22457348

Selective Galphai subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels.

Jeon, J. P., Hong, C., Park, E. J., Jeon, J. H., Cho, N. H., Kim, I. G., Choe, H., Muallem, S., Kim, H. J., So, I.

J Biol Chem

2012

22451679

Transforming growth factor-beta1 regulates Cdk5 activity in primary sensory neurons.

Utreras, E., Keller, J., Terse, A., Prochazkova, M., Iadarola, M. J., Kulkarni, A. B.

J Biol Chem

2012

22451665

Calmodulin and S100A1 protein interact with N terminus of TRPM3 channel.

Holakovska, B., Grycova, L., Jirku, M., Sulc, M., Bumba, L., Teisinger, J.

J Biol Chem

2012

22451268

Implication of AMP-activated protein kinase in transient receptor potential vanilloid type 1-mediated activation of endothelial nitric oxide synthase.

Ching, L. C., Chen, C. Y., Su, K. H., Hou, H. H., Shyue, S. K., Kou, Y. R., Lee, T. S.

Mol Med

2012

22446186

Neurotoxin-induced ER stress in mouse dopaminergic neurons involves downregulation of TRPC1 and inhibition of AKT/mTOR signaling.

Selvaraj, S., Sun, Y., Watt, J. A., Wang, S., Lei, S., Birnbaumer, L., Singh, B. B.

J Clin Invest

2012

22374181

Importance of transient receptor potential vanilloid 4 (TRPV4) in epidermal barrier function in human skin keratinocytes.

Kida, N., Sokabe, T., Kashio, M., Haruna, K., Mizuno, Y., Suga, Y., Nishikawa, K., Kanamaru, A., Hongo, M., Oba, A., Tominaga, M.

Pflugers Arch

2012

22309793

Interaction of transient receptor potential vanilloid 4 with annexin A2 and tubulin beta 5.

Huai, J., Zhang, Y., Liu, Q. M., Ge, H. Y., Arendt-Nielsen, L., Jiang, H., Yue, S. W.

Neurosci Lett

2012

22262838

Intact microtubules preserve transient receptor potential vanilloid 1 (TRPV1) functionality through receptor binding.

Storti, B., Bizzarri, R., Cardarelli, F., Beltram, F.

J Biol Chem

2012

22226147

The juvenile myoclonic epilepsy-related protein EFHC1 interacts with the redox-sensitive TRPM2 channel linked to cell death.

Katano, M., Numata, T., Aguan, K., Hara, Y., Kiyonaka, S., Yamamoto, S., Miki, T., Sawamura, S., Suzuki, T., Yamakawa, K., Mori, Y.

Cell Calcium

2012

22210847

The Ca(2+) sensor stromal interaction molecule 1 (STIM1) is necessary and sufficient for the store-operated Ca(2+) entry function of transient receptor potential canonical (TRPC) 1 and 4 channels in endothelial cells.

Sundivakkam, P. C., Freichel, M., Singh, V., Yuan, J. P., Vogel, S. M., Flockerzi, V., Malik, A. B., Tiruppathi, C.

Mol Pharmacol

2012

22201561

Opposite regulatory effects of TRPC1 and TRPC5 on neurite outgrowth in PC12 cells.

Heo, D. K., Chung, W. Y., Park, H. W., Yuan, J. P., Lee, M. G., Kim, J. Y.

Cell Signal

2012

22180838

Phosphatidylinositol 4,5-bisphosphate (PIP(2)) controls magnesium gatekeeper TRPM6 activity.

Xie, J., Sun, B., Du, J., Yang, W., Chen, H. C., Overton, J. D., Runnels, L. W., Yue, L.

Sci Rep

2011

22174419

Receptor for activated C kinase 1 (RACK1) inhibits function of transient receptor potential (TRP)-type channel Pkd2L1 through physical interaction.

Yang, J., Wang, Q., Zheng, W., Tuli, J., Li, Q., Wu, Y., Hussein, S., Dai, X. Q., Shafiei, S., Li, X. G., Shen, P. Y., Tu, J. C., Chen, X. Z.

J Biol Chem

2012

22155451

The proteoglycan syndecan 4 regulates transient receptor potential canonical 6 channels via RhoA/Rho-associated protein kinase signaling.

Liu, Y., Echtermeyer, F., Thilo, F., Theilmeier, G., Schmidt, A., Schulein, R., Jensen, B. L., Loddenkemper, C., Jankowski, V., Marcussen, N., Gollasch, M., Arendshorst, W. J., Tepel, M.

Arterioscler Thromb Vasc Biol

2012

22144671

Heteromeric canonical transient receptor potential 1 and 4 channels play a critical role in epileptiform burst firing and seizure-induced neurodegeneration.

Phelan, K. D., Mock, M. M., Kretz, O., Shwe, U. T., Kozhemyakin, M., Greenfield, L. J., Dietrich, A., Birnbaumer, L., Freichel, M., Flockerzi, V., Zheng, F.

Mol Pharmacol

2012

22135323

A TRPC5-regulated calcium signaling pathway controls dendrite patterning in the mammalian brain.

Puram, S. V., Riccio, A., Koirala, S., Ikeuchi, Y., Kim, A. H., Corfas, G., Bonni, A.

Genes Dev

2011

22101010

Phosphorylation on the Ser 824 residue of TRPV4 prefers to bind with F-actin than with microtubules to expand the cell surface area.

Shin, S. H., Lee, E. J., Hyun, S., Chun, J., Kim, Y., Kang, S. S.

Cell Signal

2012

22088247

[Impact of stromal interaction molecule 1 silencing on cell cycle of endothelial progenitor cells].

Kuang, C. Y., Huang, L., Yu, Y., Deng, M. Y., Wang, K., Qian, D. H.

Zhonghua Xin Xue Guan Bing Za Zhi

2011

22027011

A cardiac pathway of cyclic GMP-independent signaling of guanylyl cyclase A, the receptor for atrial natriuretic peptide.

Klaiber, M., Dankworth, B., Kruse, M., Hartmann, M., Nikolaev, V. O., Yang, R. B., Volker, K., Gassner, B., Oberwinkler, H., Feil, R., Freichel, M., Groschner, K., Skryabin, B. V., Frantz, S., Birnbaumer, L., Pongs, O., Kuhn, M.

Proc Natl Acad Sci U S A

2011

22001259

Adenylate cyclase/cAMP/protein kinase A signaling pathway inhibits endothelin type A receptor-operated Ca(2)(+) entry mediated via transient receptor potential canonical 6 channels.

Horinouchi, T., Higa, T., Aoyagi, H., Nishiya, T., Terada, K., Miwa, S.

J Pharmacol Exp Ther

2012

21996795

Expression and association of TRPC1 with TRPC3 during skeletal myogenesis.

Cheung, K. K., Yeung, S. S., Au, S. W., Lam, L. S., Dai, Z. Q., Li, Y. H., Yeung, E. W.

Muscle Nerve

2011

21968068

TRPC1 proteins confer PKC and phosphoinositol activation on native heteromeric TRPC1/C5 channels in vascular smooth muscle: comparative study of wild-type and TRPC1-/- mice.

Shi, J., Ju, M., Abramowitz, J., Large, W. A., Birnbaumer, L., Albert, A. P.

FASEB J

2012

21952826

Tissue transglutaminase inhibits the TRPV5-dependent calcium transport in an N-glycosylation-dependent manner.

Boros, S., Xi, Q., Dimke, H., van der Kemp, A. W., Tudpor, K., Verkaart, S., Lee, K. P., Bindels, R. J., Hoenderop, J. G.

Cell Mol Life Sci

2012

21906983

Systematic and quantitative assessment of the ubiquitin-modified proteome.

Kim, W., Bennett, E. J., Huttlin, E. L., Guo, A., Li, J., Possemato, A., Sowa, M. E., Rad, R., Rush, J., Comb, M. J., Harper, J. W., Gygi, S. P.

Mol Cell

2011

21890473

A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.

Wagner, S. A., Beli, P., Weinert, B. T., Nielsen, M. L., Cox, J., Mann, M., Choudhary, C.

Mol Cell Proteomics

2011

21871867

Electrophysiological properties of heteromeric TRPV4-C1 channels.

Ma, X., Nilius, B., Wong, J. W., Huang, Y., Yao, X.

Biochim Biophys Acta

2011

21844219

Coexpression and activation of TRPV1 suppress the activity of the KCNQ2/3 channel.

Zhang, X. F., Han, P., Neelands, T. R., McGaraughty, S., Honore, P., Surowy, C. S., Zhang, D.

J Gen Physiol

2011

21837266

Mutation of a putative S-nitrosylation site of TRPV4 protein facilitates the channel activates.

Lee, E. J., Shin, S. H., Hyun, S., Chun, J., Kang, S. S.

Animal Cells Syst (Seoul)

2011

21832182

TRPM1 forms complexes with nyctalopin in vivo and accumulates in postsynaptic compartment of ON-bipolar neurons in mGluR6-dependent manner.

Cao, Y., Posokhova, E., Martemyanov, K. A.

J Neurosci

2011

21799177

Cilostazol suppresses angiotensin II-induced vasoconstriction via protein kinase A-mediated phosphorylation of the transient receptor potential canonical 6 channel.

Nishioka, K., Nishida, M., Ariyoshi, M., Jian, Z., Saiki, S., Hirano, M., Nakaya, M., Sato, Y., Kita, S., Iwamoto, T., Hirano, K., Inoue, R., Kurose, H.

Arterioscler Thromb Vasc Biol

2011

21757714

The transient receptor potential (TRP) channel TRPC3 TRP domain and AMP-activated protein kinase binding site are required for TRPC3 activation by erythropoietin.

Hirschler-Laszkiewicz, I., Tong, Q., Waybill, K., Conrad, K., Keefer, K., Zhang, W., Chen, S. J., Cheung, J. Y., Miller, B. A.

J Biol Chem

2011

21734298

A role for nyctalopin, a small leucine-rich repeat protein, in localizing the TRP melastatin 1 channel to retinal depolarizing bipolar cell dendrites.

Pearring, J. N., Bojang, P. Jr, Shen, Y., Koike, C., Furukawa, T., Nawy, S., Gregg, R. G.

J Neurosci

2011

21672930

A key role of TRPC channels in the regulation of electromechanical activity of the developing heart.

Sabourin, J., Robin, E., Raddatz, E.

Cardiovasc Res

2011

21670282

Serine-threonine kinase with-no-lysine 4 (WNK4) controls blood pressure via transient receptor potential canonical 3 (TRPC3) in the vasculature.

Park, H. W., Kim, J. Y., Choi, S. K., Lee, Y. H., Zeng, W., Kim, K. H., Muallem, S., Lee, M. G.

Proc Natl Acad Sci U S A

2011

21576356

Molecular mechanisms of calmodulin action on TRPV5 and modulation by parathyroid hormone.

de Groot, T., Kovalevskaya, N. V., Verkaart, S., Schilderink, N., Felici, M., van der Hagen, E. A., Bindels, R. J., Vuister, G. W., Hoenderop, J. G.

Mol Cell Biol

2011

21540176

Transient receptor potential mucolipin 1 (TRPML1) and two-pore channels are functionally independent organellar ion channels.

Yamaguchi, S., Jha, A., Li, Q., Soyombo, A. A., Dickinson, G. D., Churamani, D., Brailoiu, E., Patel, S., Muallem, S.

J Biol Chem

2011

21493704

Molecular mechanisms of activation of endothelial nitric oxide synthase mediated by transient receptor potential vanilloid type 1.

Ching, L. C., Kou, Y. R., Shyue, S. K., Su, K. H., Wei, J., Cheng, L. C., Yu, Y. B., Pan, C. C., Lee, T. S.

Cardiovasc Res

2011

21402151

Functional regulation of transient receptor potential canonical 7 by cGMP-dependent protein kinase Ialpha.

Yuasa, K., Matsuda, T., Tsuji, A.

Cell Signal

2011

21307093

Pkd1l1 establishes left-right asymmetry and physically interacts with Pkd2.

Field, S., Riley, K. L., Grimes, D. T., Hilton, H., Simon, M., Powles-Glover, N., Siggers, P., Bogani, D., Greenfield, A., Norris, D. P.

Development

2011

21278253

Transient receptor potential melastatin 1 (TRPM1) is an ion-conducting plasma membrane channel inhibited by zinc ions.

Lambert, S., Drews, A., Rizun, O., Wagner, T. F., Lis, A., Mannebach, S., Plant, S., Portz, M., Meissner, M., Philipp, S. E., Oberwinkler, J.

J Biol Chem

2011

21262839

An aquaporin-4/transient receptor potential vanilloid 4 (AQP4/TRPV4) complex is essential for cell-volume control in astrocytes.

Benfenati, V., Caprini, M., Dovizio, M., Mylonakou, M. N., Ferroni, S., Ottersen, O. P., Amiry-Moghaddam, M.

Proc Natl Acad Sci U S A

2011

21224396

LAPTMs regulate lysosomal function and interact with mucolipin 1: new clues for understanding mucolipidosis type IV.

Vergarajauregui, S., Martina, J. A., Puertollano, R.

J Cell Sci

2011

21139048

Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level.

Danielsen, J. M., Sylvestersen, K. B., Bekker-Jensen, S., Szklarczyk, D., Poulsen, J. W., Horn, H., Jensen, L. J., Mailand, N., Nielsen, M. L.

Mol Cell Proteomics

2011

20926660

Ca2+-dependent desensitization of TRPV2 channels is mediated by hydrolysis of phosphatidylinositol 4,5-bisphosphate.

Mercado, J., Gordon-Shaag, A., Zagotta, W. N., Gordon, S. E.

J Neurosci

2010

20811636

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

Giannone, R. J., McDonald, H. W., Hurst, G. B., Shen, R. F., Wang, Y., Liu, Y.

PLoS One

2010

20736310

Heteromultimeric TRPML channel assemblies play a crucial role in the regulation of cell viability models and starvation-induced autophagy.

Zeevi, D. A., Lev, S., Frumkin, A., Minke, B., Bach, G.

J Cell Sci

2010

20729296

The retinitis pigmentosa protein RP2 interacts with polycystin 2 and regulates cilia-mediated vertebrate development.

Hurd, T., Zhou, W., Jenkins, P., Liu, C. J., Swaroop, A., Khanna, H., Martens, J., Hildebrandt, F., Margolis, B.

Hum Mol Genet

2010

20705915

Depletion of intracellular Ca2+ stores stimulates the translocation of vanilloid transient receptor potential 4-c1 heteromeric channels to the plasma membrane.

Ma, X., Cao, J., Luo, J., Nilius, B., Huang, Y., Ambudkar, I. S., Yao, X.

Arterioscler Thromb Vasc Biol

2010

20686800

Characterization of calmodulin binding domains in TRPV2 and TRPV5 C-tails.

Holakovska, B., Grycova, L., Bily, J., Teisinger, J.

Amino Acids

2011

20682256

Atomic force microscopy reveals the alternating subunit arrangement of the TRPP2-TRPV4 heterotetramer.

Stewart, A. P., Smith, G. D., Sandford, R. N., Edwardson, J. M.

Biophys J

2010

20660561

TRPC6 channels stimulated by angiotensin II are inhibited by TRPC1/C5 channel activity through a Ca2+- and PKC-dependent mechanism in native vascular myocytes.

Shi, J., Ju, M., Saleh, S. N., Albert, A. P., Large, W. A.

J Physiol

2010

20650893

Arresting a transient receptor potential (TRP) channel: beta-arrestin 1 mediates ubiquitination and functional down-regulation of TRPV4.

Shukla, A. K., Kim, J., Ahn, S., Xiao, K., Shenoy, S. K., Liedtke, W., Lefkowitz, R. J.

J Biol Chem

2010

20538909

Interaction between PKD1L3 and PKD2L1 through their transmembrane domains is required for localization of PKD2L1 at taste pores in taste cells of circumvallate and foliate papillae.

Ishimaru, Y., Katano, Y., Yamamoto, K., Akiba, M., Misaka, T., Roberts, R. W., Asakura, T., Matsunami, H., Abe, K.

FASEB J

2010

20492691

The TRPC2 channel forms protein-protein interactions with Homer and RTP in the rat vomeronasal organ.

Mast, T. G., Brann, J. H., Fadool, D. A.

BMC Neurosci

2010

20488539

Effect of cell swelling on ER/PM junctional interactions and channel assembly involved in SOCE.

Liu, X., Ong, H. L., Pani, B., Johnson, K., Swaim, W. B., Singh, B., Ambudkar, I.

Cell Calcium

2010

20413591

The TRPV4 channel contributes to intercellular junction formation in keratinocytes.

Sokabe, T., Fukumi-Tominaga, T., Yonemura, S., Mizuno, A., Tominaga, M.

J Biol Chem

2010

20403327

TRP channel regulates EGFR signaling in hair morphogenesis and skin barrier formation.

Cheng, X., Jin, J., Hu, L., Shen, D., Dong, X. P., Samie, M. A., Knoff, J., Eisinger, B., Liu, M. L., Huang, S. M., Caterina, M. J., Dempsey, P., Michael, L. E., Dlugosz, A. A., Andrews, N. C., Clapham, D. E., Xu, H.

Cell

2010

20378853

Isoform-selective physical coupling of TRPC3 channels to IP3 receptors in smooth muscle cells regulates arterial contractility.

Adebiyi, A., Zhao, G., Narayanan, D., Thomas-Gatewood, C. M., Bannister, J. P., Jaggar, J. H.

Circ Res

2010

20375013

Polycystin-2 activation by inositol 1,4,5-trisphosphate-induced Ca2+ release requires its direct association with the inositol 1,4,5-trisphosphate receptor in a signaling microdomain.

Sammels, E., Devogelaere, B., Mekahli, D., Bultynck, G., Missiaen, L., Parys, J. B., Cai, Y., Somlo, S., De Smedt, H.

J Biol Chem

2010

20351294

TRPC channels are necessary mediators of pathologic cardiac hypertrophy.

Wu, X., Eder, P., Chang, B., Molkentin, J. D.

Proc Natl Acad Sci U S A

2010

20346379

Involvement of Rab9 and Rab11 in the intracellular trafficking of TRPC6.

Cayouette, S., Bousquet, S. M., Francoeur, N., Dupre, E., Monet, M., Gagnon, H., Guedri, Y. B., Lavoie, C., Boulay, G.

Biochim Biophys Acta

2010

20231274

Contribution of TRPV1-TRPA1 interaction to the single channel properties of the TRPA1 channel.

Staruschenko, A., Jeske, N. A., Akopian, A. N.

J Biol Chem

2010

20194530

Expression and association of TRPC subtypes with Orai1 and STIM1 in human parathyroid.

Lu, M., Branstrom, R., Berglund, E., Hoog, A., Bjorklund, P., Westin, G., Larsson, C., Farnebo, L. O., Forsberg, L.

J Mol Endocrinol

2010

20179142

GABAA receptor associated protein (GABARAP) modulates TRPV1 expression and channel function and desensitization.

Lainez, S., Valente, P., Ontoria-Oviedo, I., Estevez-Herrera, J., Camprubi-Robles, M., Ferrer-Montiel, A., Planells-Cases, R.

FASEB J

2010

20179100

Ca2+ influx and protein scaffolding via TRPC3 sustain PKCbeta and ERK activation in B cells.

Numaga, T., Nishida, M., Kiyonaka, S., Kato, K., Katano, M., Mori, E., Kurosaki, T., Inoue, R., Hikida, M., Putney, J. W. Jr, Mori, Y.

J Cell Sci

2010

20164195

The phospholipid-binding protein SESTD1 is a novel regulator of the transient receptor potential channels TRPC4 and TRPC5.

Miehe, S., Bieberstein, A., Arnould, I., Ihdene, O., Rutten, H., Strubing, C.

J Biol Chem

2010

20107112

Role of cAMP/PKA signaling cascade in vasopressin-induced trafficking of TRPC3 channels in principal cells of the collecting duct.

Goel, M., Zuo, C. D., Schilling, W. P.

Am J Physiol Renal Physiol

2010

20095964

S165F mutation of junctophilin 2 affects Ca2+ signalling in skeletal muscle.

Woo, J. S., Hwang, J. H., Ko, J. K., Weisleder, N., Kim do, H., Ma, J., Lee, E. H.

Biochem J

2010

20093626

Functional role of vanilloid transient receptor potential 4-canonical transient receptor potential 1 complex in flow-induced Ca2+ influx.

Ma, X., Qiu, S., Luo, J., Ma, Y., Ngai, C. Y., Shen, B., Wong, C. O., Huang, Y., Yao, X.

Arterioscler Thromb Vasc Biol

2010

20022948

TRPC3 regulates agonist-stimulated Ca2+ mobilization by mediating the interaction between type I inositol 1,4,5-trisphosphate receptor, RACK1, and Orai1.

Woodard, G. E., Lopez, J. J., Jardin, I., Salido, G. M., Rosado, J. A.

J Biol Chem

2010

19996314

Cell-cell contact formation governs Ca2+ signaling by TRPC4 in the vascular endothelium: evidence for a regulatory TRPC4-beta-catenin interaction.

Graziani, A., Poteser, M., Heupel, W. M., Schleifer, H., Krenn, M., Drenckhahn, D., Romanin, C., Baumgartner, W., Groschner, K.

J Biol Chem

2010

19945390

Peptidyl-prolyl isomerase FKBP52 controls chemotropic guidance of neuronal growth cones via regulation of TRPC1 channel opening.

Shim, S., Yuan, J. P., Kim, J. Y., Zeng, W., Huang, G., Milshteyn, A., Kern, D., Muallem, S., Ming, G. L., Worley, P. F.

Neuron

2009

19932145

The interactions of the C-terminal region of the TRPC6 channel with calmodulin.

Friedlova, E., Grycova, L., Holakovska, B., Silhan, J., Janouskova, H., Sulc, M., Obsilova, V., Obsil, T., Teisinger, J.

Neurochem Int

2010

19897728

Activation of TRPC1 by STIM1 in ER-PM microdomains involves release of the channel from its scaffold caveolin-1.

Pani, B., Ong, H. L., Brazer, S. C., Liu, X., Rauser, K., Singh, B. B., Ambudkar, I. S.

Proc Natl Acad Sci U S A

2009

19885840

Functional multimerization of mucolipin channel proteins.

Curcio-Morelli, C., Zhang, P., Venugopal, B., Charles, F. A., Browning, M. F., Cantiello, H. F., Slaugenhaupt, S. A.

J Cell Physiol

2010

19879844

Polycystin-1 and -2 dosage regulates pressure sensing.

Sharif-Naeini, R., Folgering, J. H., Bichet, D., Duprat, F., Lauritzen, I., Arhatte, M., Jodar, M., Dedman, A., Chatelain, F. C., Schulte, U., Retailleau, K., Loufrani, L., Patel, A., Sachs, F., Delmas, P., Peters, D. J., Honore, E.

Cell

2009

19864432

Differential regulation of TRPV1, TRPV3, and TRPV4 sensitivity through a conserved binding site on the ankyrin repeat domain.

Phelps, C. B., Wang, R. R., Choo, S. S., Gaudet, R.

J Biol Chem

2010

19864416

Identification of the penta-EF-hand protein ALG-2 as a Ca2+-dependent interactor of mucolipin-1.

Vergarajauregui, S., Martina, J. A., Puertollano, R.

J Biol Chem

2009

19850920

The transient receptor potential channels TRPP2 and TRPC1 form a heterotetramer with a 2:2 stoichiometry and an alternating subunit arrangement.

Kobori, T., Smith, G. D., Sandford, R., Edwardson, J. M.

J Biol Chem

2009

19812035

A pathogenic C terminus-truncated polycystin-2 mutant enhances receptor-activated Ca2+ entry via association with TRPC3 and TRPC7.

Miyagi, K., Kiyonaka, S., Yamada, K., Miki, T., Mori, E., Kato, K., Numata, T., Sawaguchi, Y., Numaga, T., Kimura, T., Kanai, Y., Kawano, M., Wakamori, M., Nomura, H., Koni, I., Yamagishi, M., Mori, Y.

J Biol Chem

2009

19812031

Regulation of TRPC1 and TRPC4 cation channels requires an alpha1-syntrophin-dependent complex in skeletal mouse myotubes.

Sabourin, J., Lamiche, C., Vandebrouck, A., Magaud, C., Rivet, J., Cognard, C., Bourmeyster, N., Constantin, B.

J Biol Chem

2009

19801576

PRKCSH/80K-H, the protein mutated in polycystic liver disease, protects polycystin-2/TRPP2 against HERP-mediated degradation.

Gao, H., Wang, Y., Wegierski, T., Skouloudaki, K., Putz, M., Fu, X., Engel, C., Boehlke, C., Peng, H., Kuehn, E. W., Kim, E., Kramer-Zucker, A., Walz, G.

Hum Mol Genet

2010

19726544

Analysis of the cytoplasmic interaction between polycystin-1 and polycystin-2.

Casuscelli, J., Schmidt, S., DeGray, B., Petri, E. T., Celic, A., Folta-Stogniew, E., Ehrlich, B. E., Boggon, T. J.

Am J Physiol Renal Physiol

2009

19689790

Abnormal expression, localization and interaction of canonical transient receptor potential ion channels in human breast cancer cell lines and tissues: a potential target for breast cancer diagnosis and therapy.

Aydar, E., Yeo, S., Djamgoz, M., Palmer, C.

Cancer Cell Int

2009

19557826

A potentially dynamic lysosomal role for the endogenous TRPML proteins.

Zeevi, D. A., Frumkin, A., Offen-Glasner, V., Kogot-Levin, A., Bach, G.

J Pathol

2009

19556541

Structural and molecular basis of the assembly of the TRPP2/PKD1 complex.

Yu, Y., Ulbrich, M. H., Li, M. H., Buraei, Z., Chen, X. Z., Ong, A. C., Tong, L., Isacoff, E. Y., Yang, J.

Proc Natl Acad Sci U S A

2009

19522758

The Ca(2+) channel TRPML3 regulates membrane trafficking and autophagy.

Kim, H. J., Soyombo, A. A., Tjon-Kon-Sang, S., So, I., Muallem, S.

Traffic

2009

19502552

Inhibition of TRPC1/TRPC3 by PKG contributes to NO-mediated vasorelaxation.

Chen, J., Crossland, R. F., Noorani, M. M., Marrelli, S. P.

Am J Physiol Heart Circ Physiol

2009

19351713

Regulation of transient receptor potential canonical channel 1 (TRPC1) by sphingosine 1-phosphate in C2C12 myoblasts and its relevance for a role of mechanotransduction in skeletal muscle differentiation.

Formigli, L., Sassoli, C., Squecco, R., Bini, F., Martinesi, M., Chellini, F., Luciani, G., Sbrana, F., Zecchi-Orlandini, S., Francini, F., Meacci, E.

J Cell Sci

2009

19332490

TRPC1 and STIM1 mediate capacitative Ca2+ entry in mouse pulmonary arterial smooth muscle cells.

Ng, L. C., McCormack, M. D., Airey, J. A., Singer, C. A., Keller, P. S., Shen, X. M., Hume, J. R.

J Physiol

2009

19329436

Regulation of the epithelial Mg2+ channel TRPM6 by estrogen and the associated repressor protein of estrogen receptor activity (REA).

Cao, G., van der Wijst, J., van der Kemp, A., van Zeeland, F., Bindels, R. J., Hoenderop, J. G.

J Biol Chem

2009

19307462

Interaction between TRPC1/TRPC4 assembly and STIM1 contributes to store-operated Ca2+ entry in mesangial cells.

Sours-Brothers, S., Ding, M., Graham, S., Ma, R.

Exp Biol Med (Maywood)

2009

19295174

Endogenous expression of TRPV5 and TRPV6 calcium channels in human leukemia K562 cells.

Semenova, S. B., Vassilieva, I. O., Fomina, A. F., Runov, A. L., Negulyaev, Y. A.

Am J Physiol Cell Physiol

2009

19289841

Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound.

Kiyonaka, S., Kato, K., Nishida, M., Mio, K., Numaga, T., Sawaguchi, Y., Yoshida, T., Wakamori, M., Mori, E., Numata, T., Ishii, M., Takemoto, H., Ojida, A., Watanabe, K., Uemura, A., Kurose, H., Morii, T., Kobayashi, T., Sato, Y., Sato, C., Hamachi, I., Mori, Y.

Proc Natl Acad Sci U S A

2009

19277847

Glutamate at position 227 of junctophilin-2 is involved in binding to TRPC3.

Woo, J. S., Hwang, J. H., Ko, J. K., Kim do, H., Ma, J., Lee, E. H.

Mol Cell Biochem

2009

19260825

Dynamic interaction of hTRPC6 with the Orai1-STIM1 complex or hTRPC3 mediates its role in capacitative or non-capacitative Ca(2+) entry pathways.

Jardin, I., Gomez, L. J., Salido, G. M., Rosado, J. A.

Biochem J

2009

19228695

Native Store-operated Ca2+ Influx Requires the Channel Function of Orai1 and TRPC1.

Kim, M. S., Zeng, W., Yuan, J. P., Shin, D. M., Worley, P. F., Muallem, S.

J Biol Chem

2009

19228120

Identification of dimer interactions required for the catalytic activity of the TRPM7 alpha-kinase domain.

Crawley, S. W., Cote, G. P.

Biochem J

2009

19223122

Cross-inhibition between native and recombinant TRPV1 and P2X(3) receptors.

Stanchev, D., Blosa, M., Milius, D., Gerevich, Z., Rubini, P., Schmalzing, G., Eschrich, K., Schaefer, M., Wirkner, K., Illes, P.

Pain

2009

19193631

The multimeric structure of polycystin-2 (TRPP2): structural-functional correlates of homo- and hetero-multimers with TRPC1.

Zhang, P., Luo, Y., Chasan, B., Gonzalez-Perrett, S., Montalbetti, N., Timpanaro, G. A., Cantero Mdel, R., Ramos, A. J., Goldmann, W. H., Zhou, J., Cantiello, H. F.

Hum Mol Genet

2009

19168436

TRPC1 associates with BK(Ca) channel to form a signal complex in vascular smooth muscle cells.

Kwan, H. Y., Shen, B., Ma, X., Kwok, Y. C., Huang, Y., Man, Y. B., Yu, S., Yao, X.

Circ Res

2009

19155296

Transient receptor potential type vanilloid 1 suppresses skin carcinogenesis.

Bode, A. M., Cho, Y. Y., Zheng, D., Zhu, F., Ericson, M. E., Ma, W. Y., Yao, K., Dong, Z.

Cancer Res

2009

19117012

Chaperone-mediated autophagy is defective in mucolipidosis type IV.

Venugopal, B., Mesires, N. T., Kennedy, J. C., Curcio-Morelli, C., Laplante, J. M., Dice, J. F., Slaugenhaupt, S. A.

J Cell Physiol

2009

19074769

TRPC3 activation by erythropoietin is modulated by TRPC6.

Hirschler-Laszkiewicz, I., Tong, Q., Conrad, K., Zhang, W., Flint, W. W., Barber, A. J., Barber, D. L., Cheung, J. Y., Miller, B. A.

J Biol Chem

2009

19052258

Caveolin-1 scaffold domain interacts with TRPC1 and IP3R3 to regulate Ca2+ store release-induced Ca2+ entry in endothelial cells.

Sundivakkam, P. C., Kwiatek, A. M., Sharma, T. T., Minshall, R. D., Malik, A. B., Tiruppathi, C.

Am J Physiol Cell Physiol

2009

19052171

Canonical transient receptor potential channel (TRPC)3 and TRPC6 associate with large-conductance Ca2+-activated K+ (BKCa) channels: role in BKCa trafficking to the surface of cultured podocytes.

Kim, E. Y., Alvarez-Baron, C. P., Dryer, S. E.

Mol Pharmacol

2009

19033444

Tyrosine phosphorylation modulates the activity of TRPV4 in response to defined stimuli.

Wegierski, T., Lewandrowski, U., Muller, B., Sickmann, A., Walz, G.

J Biol Chem

2009

19027987

Functional interaction of the cation channel transient receptor potential vanilloid 4 (TRPV4) and actin in volume regulation.

Becker, D., Bereiter-Hahn, J., Jendrach, M.

Eur J Cell Biol

2009

18836075

Syntaxin 5 regulates the endoplasmic reticulum channel-release properties of polycystin-2.

Geng, L., Boehmerle, W., Maeda, Y., Okuhara, D. Y., Tian, X., Yu, Z., Choe, C. U., Anyatonwu, G. I., Ehrlich, B. E., Somlo, S.

Proc Natl Acad Sci U S A

2008

18826956

IP3 receptor binds to and sensitizes TRPV4 channel to osmotic stimuli via a calmodulin-binding site.

Garcia-Elias, A., Lorenzo, I. M., Vicente, R., Valverde, M. A.

J Biol Chem

2008

18802106

Secretogranin III directs secretory vesicle biogenesis in mast cells in a manner dependent upon interaction with chromogranin A.

Prasad, P., Yanagihara, A. A., Small-Howard, A. L., Turner, H., Stokes, A. J.

J Immunol

2008

18802022

Interactions, functions, and independence of plasma membrane STIM1 and TRPC1 in vascular smooth muscle cells.

Li, J., Sukumar, P., Milligan, C. J., Kumar, B., Ma, Z. Y., Munsch, C. M., Jiang, L. H., Porter, K. E., Beech, D. J.

Circ Res

2008

18782757

Polycystin-2 expression is regulated by a PC2-binding domain in the intracellular portion of fibrocystin.

Kim, I., Li, C., Liang, D., Chen, X. Z., Coffy, R. J., Ma, J., Zhao, P., Wu, G.

J Biol Chem

2008

18755685

TRPC3 controls agonist-stimulated intracellular Ca2+ release by mediating the interaction between inositol 1,4,5-trisphosphate receptor and RACK1.

Bandyopadhyay, B. C., Ong, H. L., Lockwich, T. P., Liu, X., Paria, B. C., Singh, B. B., Ambudkar, I. S.

J Biol Chem

2008

18701070

Proinflammatory mediators modulate the heat-activated ion channel TRPV1 via the scaffolding protein AKAP79/150.

Zhang, X., Li, L., McNaughton, P. A.

Neuron

2008

18695040

TRPP2 and TRPV4 form a polymodal sensory channel complex.

Kottgen, M., Buchholz, B., Garcia-Gonzalez, M. A., Kotsis, F., Fu, X., Doerken, M., Boehlke, C., Steffl, D., Tauber, R., Wegierski, T., Nitschke, R., Suzuki, M., Kramer-Zucker, A., Germino, G. G., Watnick, T., Prenen, J., Nilius, B., Kuehn, E. W., Walz, G.

J Cell Biol

2008

18664456

Polycystin-2 down-regulates cell proliferation via promoting PERK-dependent phosphorylation of eIF2alpha.

Liang, G., Yang, J., Wang, Z., Li, Q., Tang, Y., Chen, X. Z.

Hum Mol Genet

2008

18644792

Orai1 mediates the interaction between STIM1 and hTRPC1 and regulates the mode of activation of hTRPC1-forming Ca2+ channels.

Jardin, I., Lopez, J. J., Salido, G. M., Rosado, J. A.

J Biol Chem

2008

18617565

Nitric oxide-cGMP-protein kinase G pathway negatively regulates vascular transient receptor potential channel TRPC6.

Takahashi, S., Lin, H., Geshi, N., Mori, Y., Kawarabayashi, Y., Takami, N., Mori, M. X., Honda, A., Inoue, R.

J Physiol

2008

18606998

Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1.

Cha, S. K., Ortega, B., Kurosu, H., Rosenblatt, K. P., Kuro-O, M., Huang, C. L.

Proc Natl Acad Sci U S A

2008

18544631

TRPC1 binds to caveolin-3 and is regulated by Src kinase - role in Duchenne muscular dystrophy.

Gervasio, O. L., Whitehead, N. P., Yeung, E. W., Phillips, W. D., Allen, D. G.

J Cell Sci

2008

18535624

Off-response property of an acid-activated cation channel complex PKD1L3-PKD2L1.

Inada, H., Kawabata, F., Ishimaru, Y., Fushiki, T., Matsunami, H., Tominaga, M.

EMBO Rep

2008

18502908

ATP/UTP activate cation-permeable channels with TRPC3/7 properties in rat cardiomyocytes.

Alvarez, J., Coulombe, A., Cazorla, O., Ugur, M., Rauzier, J. M., Magyar, J., Mathieu, E. L., Boulay, G., Souto, R., Bideaux, P., Salazar, G., Rassendren, F., Lacampagne, A., Fauconnier, J., Vassort, G.

Am J Physiol Heart Circ Physiol

2008

18495742

The beta-glucuronidase klotho exclusively activates the epithelial Ca2+ channels TRPV5 and TRPV6.

Lu, P., Boros, S., Chang, Q., Bindels, R. J., Hoenderop, J. G.

Nephrol Dial Transplant

2008

18463244

Protein kinase A anchoring via AKAP150 is essential for TRPV1 modulation by forskolin and prostaglandin E2 in mouse sensory neurons.

Schnizler, K., Shutov, L. P., Van Kanegan, M. J., Merrill, M. A., Nichols, B., McKnight, G. S., Strack, S., Hell, J. W., Usachev, Y. M.

J Neurosci

2008

18455988

Pirt, a phosphoinositide-binding protein, functions as a regulatory subunit of TRPV1.

Kim, A. Y., Tang, Z., Liu, Q., Patel, K. N., Maag, D., Geng, Y., Dong, X.

Cell

2008

18445599

The human TRPV6 channel protein is associated with cyclophilin B in human placenta.

Stumpf, T., Zhang, Q., Hirnet, D., Lewandrowski, U., Sickmann, A., Wissenbach, U., Dorr, J., Lohr, C., Deitmer, J. W., Fecher-Trost, C.

J Biol Chem

2008

18430726

Lipid rafts determine clustering of STIM1 in endoplasmic reticulum-plasma membrane junctions and regulation of store-operated Ca2+ entry (SOCE).

Pani, B., Ong, H. L., Liu, X., Rauser, K., Ambudkar, I. S., Singh, B. B.

J Biol Chem

2008

18392847

Identification of Nipsnap1 as a novel auxiliary protein inhibiting TRPV6 activity.

Schoeber, J. P., Topala, C. N., Lee, K. P., Lambers, T. T., Ricard, G., van der Kemp, A. W., Huynen, M. A., Hoenderop, J. G., Bindels, R. J.

Pflugers Arch

2008

18381233

A-kinase anchoring protein mediates TRPV1 thermal hyperalgesia through PKA phosphorylation of TRPV1.

Jeske, N. A., Diogenes, A., Ruparel, N. B., Fehrenbacher, J. C., Henry, M., Akopian, A. N., Hargreaves, K. M.

Pain

2008

18378772

IP3 sensitizes TRPV4 channel to the mechano- and osmotransducing messenger 5'-6'-epoxyeicosatrienoic acid.

Fernandes, J., Lorenzo, I. M., Andrade, Y. N., Garcia-Elias, A., Serra, S. A., Fernandez-Fernandez, J. M., Valverde, M. A.

J Cell Biol

2008

18356201

Diverse properties of store-operated TRPC channels activated by protein kinase C in vascular myocytes.

Saleh, S. N., Albert, A. P., Peppiatt-Wildman, C. M., Large, W. A.

J Physiol

2008

18326500

Functional requirement for Orai1 in store-operated TRPC1-STIM1 channels.

Cheng, K. T., Liu, X., Ong, H. L., Ambudkar, I. S.

J Biol Chem

2008

18323855

Formation of a new receptor-operated channel by heteromeric assembly of TRPP2 and TRPC1 subunits.

Bai, C. X., Giamarchi, A., Rodat-Despoix, L., Padilla, F., Downs, T., Tsiokas, L., Delmas, P.

EMBO Rep

2008

18287061

Functional interactions among Orai1, TRPCs, and STIM1 suggest a STIM-regulated heteromeric Orai/TRPC model for SOCE/Icrac channels.

Liao, Y., Erxleben, C., Abramowitz, J., Flockerzi, V., Zhu, M. X., Armstrong, D. L., Birnbaumer, L.

Proc Natl Acad Sci U S A

2008

18276585

TRPC3 is the erythropoietin-regulated calcium channel in human erythroid cells.

Tong, Q., Hirschler-Laszkiewicz, I., Zhang, W., Conrad, K., Neagley, D. W., Barber, D. L., Cheung, J. Y., Miller, B. A.

J Biol Chem

2008

18273441

Kidney injury molecule 1 (Kim1) is a novel ciliary molecule and interactor of polycystin 2.

Kuehn, E. W., Hirt, M. N., John, A. K., Muehlenhardt, P., Boehlke, C., Putz, M., Kramer-Zucker, A. G., Bashkurov, M., van de Weyer, P. S., Kotsis, F., Walz, G.

Biochem Biophys Res Commun

2007

18268005

Mice lacking Homer 1 exhibit a skeletal myopathy characterized by abnormal transient receptor potential channel activity.

Stiber, J. A., Zhang, Z. S., Burch, J., Eu, J. P., Zhang, S., Truskey, G. A., Seth, M., Yamaguchi, N., Meissner, G., Shah, R., Worley, P. F., Williams, R. S., Rosenberg, P. B.

Mol Cell Biol

2008

18262493

TRPM4b channel suppresses store-operated Ca2+ entry by a novel protein-protein interaction with the TRPC3 channel.

Park, J. Y., Hwang, E. M., Yarishkin, O., Seo, J. H., Kim, E., Yoo, J., Yi, G. S., Kim, D. G., Park, N., Ha, C. M., La, J. H., Kang, D., Han, J., Oh, U., Hong, S. G.

Biochem Biophys Res Commun

2008

18261457

Interaction with dopamine D2 receptor enhances expression of transient receptor potential channel 1 at the cell surface.

Hannan, M. A., Kabbani, N., Paspalas, C. D., Levenson, R.

Biochim Biophys Acta

2008

18258429

RACK1 inhibits TRPM6 activity via phosphorylation of the fused alpha-kinase domain.

Cao, G., Thebault, S., van der Wijst, J., van der Kemp, A., Lasonder, E., Bindels, R. J., Hoenderop, J. G.

Curr Biol

2008

18256307

Mediation of angiotensin II-induced Ca2+ signaling by polycystin 2 in glomerular mesangial cells.

Du, J., Ding, M., Sours-Brothers, S., Graham, S., Ma, R.

Am J Physiol Renal Physiol

2008

18249094

Functional relevance of the de novo coupling between hTRPC1 and type II IP3 receptor in store-operated Ca2+ entry in human platelets.

Jardin, I., Lopez, J. J., Salido, G. M., Rosado, J. A.

Cell Signal

2008

18235101

Nek8 regulates the expression and localization of polycystin-1 and polycystin-2.

Sohara, E., Luo, Y., Zhang, J., Manning, D. K., Beier, D. R., Zhou, J.

J Am Soc Nephrol

2008

18235088

Fibrocystin/polyductin modulates renal tubular formation by regulating polycystin-2 expression and function.

Kim, I., Fu, Y., Hui, K., Moeckel, G., Mai, W., Li, C., Liang, D., Zhao, P., Ma, J., Chen, X. Z., George, A. L. Jr, Coffey, R. J., Feng, Z. P., Wu, G.

J Am Soc Nephrol

2008

18234883

Interaction of transient receptor potential vanilloid 4, integrin, and SRC tyrosine kinase in mechanical hyperalgesia.

Alessandri-Haber, N., Dina, O. A., Joseph, E. K., Reichling, D. B., Levine, J. D.

J Neurosci

2008

18215135

TRPC3-interacting triadic proteins in skeletal muscle.

Woo, J. S., Kim do, H., Allen, P. D., Lee, E. H.

Biochem J

2008

18205297

Analysis of TRPC3-interacting proteins by tandem mass spectrometry.

Lockwich, T., Pant, J., Makusky, A., Jankowska-Stephens, E., Kowalak, J. A., Markey, S. P., Ambudkar, I. S.

J Proteome Res

2008

18191041

Intracellular Ca2+ store depletion induces the formation of macromolecular complexes involving hTRPC1, hTRPC6, the type II IP3 receptor and SERCA3 in human platelets.

Redondo, P. C., Jardin, I., Lopez, J. J., Salido, G. M., Rosado, J. A.

Biochim Biophys Acta

2008

18187190

The annexin 2-S100A10 complex and its association with TRPV6 is regulated by cAMP/PKA/CnA in airway and gut epithelia.

Borthwick, L. A., Neal, A., Hobson, L., Gerke, V., Robson, L., Muimo, R.

Cell Calcium

2008

18178578

Polycystin-2 is regulated by endoplasmic reticulum-associated degradation.

Liang, G., Li, Q., Tang, Y., Kokame, K., Kikuchi, T., Wu, G., Chen, X. Z.

Hum Mol Genet

2008

18174177

Stimulus-specific modulation of the cation channel TRPV4 by PACSIN 3.

D'hoedt, D., Owsianik, G., Prenen, J., Cuajungco, M. P., Grimm, C., Heller, S., Voets, T., Nilius, B.

J Biol Chem

2008

18068335

SERCA2b and 3 play a regulatory role in store-operated calcium entry in human platelets.

Redondo, P. C., Salido, G. M., Pariente, J. A., Sage, S. O., Rosado, J. A.

Cell Signal

2008

18063480

Interaction between protein kinase D1 and transient receptor potential V1 in primary sensory neurons is involved in heat hypersensitivity.

Zhu, H., Yang, Y., Zhang, H., Han, Y., Li, Y., Zhang, Y., Yin, D., He, Q., Zhao, Z., Blumberg, P. M., Han, J., Wang, Y.

Pain

2008

18048348

The spectrin cytoskeleton influences the surface expression and activation of human transient receptor potential channel 4 channels.

Odell, A. F., Van Helden, D. F., Scott, J. L.

J Biol Chem

2008

17988215

Mucolipin 1 channel activity is regulated by protein kinase A-mediated phosphorylation.

Vergarajauregui, S., Oberdick, R., Kiselyov, K., Puertollano, R.

Biochem J

2008

17944866

Direct binding of alpha-actinin enhances TRPP3 channel activity.

Li, Q., Dai, X. Q., Shen, P. Y., Wu, Y., Long, W., Chen, C. X., Hussain, Z., Wang, S., Chen, X. Z.

J Neurochem

2007

17932042

OS-9 regulates the transit and polyubiquitination of TRPV4 in the endoplasmic reticulum.

Wang, Y., Fu, X., Gaiser, S., Kottgen, M., Kramer-Zucker, A., Walz, G., Wegierski, T.

J Biol Chem

2007

17913834

Association of VASP with TRPC4 in PKG-mediated inhibition of the store-operated calcium response in mesangial cells.

Wang, X., Pluznick, J. L., Settles, D. C., Sansom, S. C.

Am J Physiol Renal Physiol

2007

17892531

hTRPC1-associated alpha-actinin, and not hTRPC1 itself, is tyrosine phosphorylated during human platelet activation.

Redondo, P. C., Harper, A. G., Harper, M. T., Brownlow, S. L., Rosado, J. A., Sage, S. O.

J Thromb Haemost

2007

17850865

RNF24, a new TRPC interacting protein, causes the intracellular retention of TRPC.

Lussier, M. P., Lepage, P. K., Bousquet, S. M., Boulay, G.

Cell Calcium

2008

17699554

Vasopressin-induced membrane trafficking of TRPC3 and AQP2 channels in cells of the rat renal collecting duct.

Goel, M., Sinkins, W. G., Zuo, C. D., Hopfer, U., Schilling, W. P.

Am J Physiol Renal Physiol

2007

17684020

Snapin, a new regulator of receptor signaling, augments alpha1A-adrenoceptor-operated calcium influx through TRPC6.

Suzuki, F., Morishima, S., Tanaka, T., Muramatsu, I.

J Biol Chem

2007

17681754

Dual role of tubulin-cytoskeleton in store-operated calcium entry in human platelets.

Redondo, P. C., Harper, A. G., Sage, S. O., Rosado, J. A.

Cell Signal

2007

17645868

PDZ domain-containing protein as a physiological modulator of TRPV6.

Kim, H. J., Yang, D. K., So, I.

Biochem Biophys Res Commun

2007

17636028

TAZ promotes PC2 degradation through a SCFbeta-Trcp E3 ligase complex.

Tian, Y., Kolb, R., Hong, J. H., Carroll, J., Li, D., You, J., Bronson, R., Yaffe, M. B., Zhou, J., Benjamin, T.

Mol Cell Biol

2007

17624425

The first ankyrin-like repeat is the minimum indispensable key structure for functional assembly of homo- and heteromeric TRPC4/TRPC5 channels.

Schindl, R., Frischauf, I., Kahr, H., Fritsch, R., Krenn, M., Derndl, A., Vales, E., Muik, M., Derler, I., Groschner, K., Romanin, C.

Cell Calcium

2008

17620599

Functional specialization of beta-arrestin interactions revealed by proteomic analysis.

Xiao, K., McClatchy, D. B., Shukla, A. K., Zhao, Y., Chen, M., Shenoy, S. K., Yates, J. R. 3rd, Lefkowitz, R. J.

Proc Natl Acad Sci U S A

2007

17486119

STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels.

Yuan, J. P., Zeng, W., Huang, G. N., Worley, P. F., Muallem, S.

Nat Cell Biol

2007

17416589

Genetic evidence supporting caveolae microdomain regulation of calcium entry in endothelial cells.

Murata, T., Lin, M. I., Stan, R. V., Bauer, P. M., Yu, J., Sessa, W. C.

J Biol Chem

2007

17404231

Regulation of ryanodine receptor-dependent calcium signaling by polycystin-2.

Anyatonwu, G. I., Estrada, M., Tian, X., Somlo, S., Ehrlich, B. E.

Proc Natl Acad Sci U S A

2007

17360584

Orai proteins interact with TRPC channels and confer responsiveness to store depletion.

Liao, Y., Erxleben, C., Yildirim, E., Abramowitz, J., Armstrong, D. L., Birnbaumer, L.

Proc Natl Acad Sci U S A

2007

17298389

Identification and characterisation of novel tubulin-binding motifs located within the C-terminus of TRPV1.

Goswami, C., Hucho, T. B., Hucho, F.

J Neurochem

2007

17283055

Fibrocystin/polyductin, found in the same protein complex with polycystin-2, regulates calcium responses in kidney epithelia.

Wang, S., Zhang, J., Nauli, S. M., Li, X., Starremans, P. G., Luo, Y., Roberts, K. A., Zhou, J.

Mol Cell Biol

2007

17251321

Regulation of TRP channel TRPM2 by the tyrosine phosphatase PTPL1.

Zhang, W., Tong, Q., Conrad, K., Wozney, J., Cheung, J. Y., Miller, B. A.

Am J Physiol Cell Physiol

2007

17224452

Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx. Evidence for similarities in store-operated and calcium release-activated calcium channel components.

Ong, H. L., Cheng, K. T., Liu, X., Bandyopadhyay, B. C., Paria, B. C., Soboloff, J., Pani, B., Gwack, Y., Srikanth, S., Singh, B. B., Gill, D. L., Ambudkar, I. S.

J Biol Chem

2007

17202249

Regulation of capacitative calcium entries by alpha1-syntrophin: association of TRPC1 with dystrophin complex and the PDZ domain of alpha1-syntrophin.

Vandebrouck, A., Sabourin, J., Rivet, J., Balghi, H., Sebille, S., Kitzis, A., Raymond, G., Cognard, C., Bourmeyster, N., Constantin, B.

FASEB J

2007

17197020

Identification of tyrosines in the putative regulatory site of the Ca2+ channel TRPV6.

Sternfeld, L., Anderie, I., Schmid, A., Al-Shaldi, H., Krause, E., Magg, T., Schreiner, D., Hofer, H. W., Schulz, I.

Cell Calcium

2007

17194758

Cyclin-dependent kinase 5 modulates nociceptive signaling through direct phosphorylation of transient receptor potential vanilloid 1.

Pareek, T. K., Keller, J., Kesavapany, S., Agarwal, N., Kuner, R., Pant, H. C., Iadarola, M. J., Brady, R. O., Kulkarni, A. B.

Proc Natl Acad Sci U S A

2007

17156765

Insulin potentiates TRPC3-mediated cation currents in normal but not in insulin-resistant mouse cardiomyocytes.

Fauconnier, J., Lanner, J. T., Sultan, A., Zhang, S. J., Katz, A., Bruton, J. D., Westerblad, H.

Cardiovasc Res

2007

17129578

Phospholipase C-dependent control of cardiac calcium homeostasis involves a TRPC3-NCX1 signaling complex.

Eder, P., Probst, D., Rosker, C., Poteser, M., Wolinski, H., Kohlwein, S. D., Romanin, C., Groschner, K.

Cardiovasc Res

2007

17110928

The HECT ubiquitin ligase AIP4 regulates the cell surface expression of select TRP channels.

Wegierski, T., Hill, K., Schaefer, M., Walz, G.

EMBO J

2006

17088214

The TRPM7 ion channel functions in cholinergic synaptic vesicles and affects transmitter release.

Krapivinsky, G., Mochida, S., Krapivinsky, L., Cibulsky, S. M., Clapham, D. E.

Neuron

2006

17074976

Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane.

Stein, A. T., Ufret-Vincenty, C. A., Hua, L., Santana, L. F., Gordon, S. E.

J Gen Physiol

2006

17012351

TRPC3 channels colocalize with Na+/Ca2+ exchanger and Na+ pump in axial component of transverse-axial tubular system of rat ventricle.

Goel, M., Zuo, C. D., Sinkins, W. G., Schilling, W. P.

Am J Physiol Heart Circ Physiol

2007

17008358

Kinesin-2 mediates physical and functional interactions between polycystin-2 and fibrocystin.

Wu, Y., Dai, X. Q., Li, Q., Chen, C. X., Mai, W., Hussain, Z., Long, W., Montalbetti, N., Li, G., Glynne, R., Wang, S., Cantiello, H. F., Wu, G., Chen, X. Z.

Hum Mol Genet

2006

16959851

Dynamic but not constitutive association of calmodulin with rat TRPV6 channels enables fine tuning of Ca2+-dependent inactivation.

Derler, I., Hofbauer, M., Kahr, H., Fritsch, R., Muik, M., Kepplinger, K., Hack, M. E., Moritz, S., Schindl, R., Groschner, K., Romanin, C.

J Physiol

2006

16950792

Polycystin-2 cation channel function is under the control of microtubular structures in primary cilia of renal epithelial cells.

Li, Q., Montalbetti, N., Wu, Y., Ramos, A., Raychowdhury, M. K., Chen, X. Z., Cantiello, H. F.

J Biol Chem

2006

16916799

Identification of two domains involved in the assembly of transient receptor potential canonical channels.

Lepage, P. K., Lussier, M. P., Barajas-Martinez, H., Bousquet, S. M., Blanchard, A. P., Francoeur, N., Dumaine, R., Boulay, G.

J Biol Chem

2006

16906149

STIM1 carboxyl-terminus activates native SOC, I(crac) and TRPC1 channels.

Huang, G. N., Zeng, W., Kim, J. Y., Yuan, J. P., Han, L., Muallem, S., Worley, P. F.

Nat Cell Biol

2006

16905188

Signaling proteins in raft-like microdomains are essential for Ca2+ wave propagation in glial cells.

Weerth, S. H., Holtzclaw, L. A., Russell, J. T.

Cell Calcium

2007

16899571

Pregnancy-enhanced store-operated Ca2+ channel function in uterine artery endothelial cells is associated with enhanced agonist-specific transient receptor potential channel 3-inositol 1,4,5-trisphosphate receptor 2 interaction.

Gifford, S. M., Yi, F. X., Bird, I. M.

J Endocrinol

2006

16895908

RGS2 inhibits the epithelial Ca2+ channel TRPV6.

Schoeber, J. P., Topala, C. N., Wang, X., Diepens, R. J., Lambers, T. T., Hoenderop, J. G., Bindels, R. J.

J Biol Chem

2006

16891422

Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor.

Ishimaru, Y., Inada, H., Kubota, M., Zhuang, H., Tominaga, M., Matsunami, H.

Proc Natl Acad Sci U S A

2006

16887806

Homer 1 mediates store- and inositol 1,4,5-trisphosphate receptor-dependent translocation and retrieval of TRPC3 to the plasma membrane.

Kim, J. Y., Zeng, W., Kiselyov, K., Yuan, J. P., Dehoff, M. H., Mikoshiba, K., Worley, P. F., Muallem, S.

J Biol Chem

2006

16875688

Identification and characterization of GSRP-56, a novel Golgi-localized spectrin repeat-containing protein.

Kobayashi, Y., Katanosaka, Y., Iwata, Y., Matsuoka, M., Shigekawa, M., Wakabayashi, S.

Exp Cell Res

2006

16870612

Interaction of STIM1 with endogenously expressed human canonical TRP1 upon depletion of intracellular Ca2+ stores.

Lopez, J. J., Salido, G. M., Pariente, J. A., Rosado, J. A.

J Biol Chem

2006

16822931

Caveolin-1 regulates store-operated Ca2+ influx by binding of its scaffolding domain to transient receptor potential channel-1 in endothelial cells.

Kwiatek, A. M., Minshall, R. D., Cool, D. R., Skidgel, R. A., Malik, A. B., Tiruppathi, C.

Mol Pharmacol

2006

16818374

Interaction between TRPC channel subunits in endothelial cells.

Antoniotti, S., Fiorio Pla, A., Barral, S., Scalabrino, O., Munaron, L., Lovisolo, D.

J Recept Signal Transduct Res

2006

16763551

Calbindin-D28K dynamically controls TRPV5-mediated Ca2+ transport.

Lambers, T. T., Mahieu, F., Oancea, E., Hoofd, L., de Lange, F., Mensenkamp, A. R., Voets, T., Nilius, B., Clapham, D. E., Hoenderop, J. G., Bindels, R. J.

EMBO J

2006

16627472

PACSINs bind to the TRPV4 cation channel. PACSIN 3 modulates the subcellular localization of TRPV4.

Cuajungco, M. P., Grimm, C., Oshima, K., D'hoedt, D., Nilius, B., Mensenkamp, A. R., Bindels, R. J., Plomann, M., Heller, S.

J Biol Chem

2006

16609150

More than colocalizing with polycystin-1, polycystin-L is in the centrosome.

Bui-Xuan, E. F., Li, Q., Chen, X. Z., Boucher, C. A., Sandford, R., Zhou, J., Basora, N.

Am J Physiol Renal Physiol

2006

16606612

Lysosomal localization of TRPML3 depends on TRPML2 and the mucolipidosis-associated protein TRPML1.

Venkatachalam, K., Hofmann, T., Montell, C.

J Biol Chem

2006

16571723

A role for AQP5 in activation of TRPV4 by hypotonicity: concerted involvement of AQP5 and TRPV4 in regulation of cell volume recovery.

Liu, X., Bandyopadhyay, B. C., Nakamoto, T., Singh, B., Liedtke, W., Melvin, J. E., Ambudkar, I.

J Biol Chem

2006

16565876

Interaction of the epithelial Ca2+ channels TRPV5 and TRPV6 with the intestine- and kidney-enriched PDZ protein NHERF4.

van de Graaf, S. F., Hoenderop, J. G., van der Kemp, A. W., Gisler, S. M., Bindels, R. J.

Pflugers Arch

2006

16537542

TRPC3 and TRPC4 associate to form a redox-sensitive cation channel. Evidence for expression of native TRPC3-TRPC4 heteromeric channels in endothelial cells.

Poteser, M., Graziani, A., Rosker, C., Eder, P., Derler, I., Kahr, H., Zhu, M. X., Romanin, C., Groschner, K.

J Biol Chem

2006

16510717

TRPV1 recapitulates native capsaicin receptor in sensory neurons in association with Fas-associated factor 1.

Kim, S., Kang, C., Shin, C. Y., Hwang, S. W., Yang, Y. D., Shim, W. S., Park, M. Y., Kim, E., Kim, M., Kim, B. M., Cho, H., Shin, Y., Oh, U.

J Neurosci

2006

16500902

Structural characterization of the split pleckstrin homology domain in phospholipase C-gamma1 and its interaction with TRPC3.

Wen, W., Yan, J., Zhang, M.

J Biol Chem

2006

16500080

TRPA1 is a substrate for de-ubiquitination by the tumor suppressor CYLD.

Stokes, A., Wakano, C., Koblan-Huberson, M., Adra, C. N., Fleig, A., Turner, H.

Cell Signal

2006

16469785

Calcium-sensing mechanism in TRPC5 channels contributing to retardation of neurite outgrowth.

Hui, H., McHugh, D., Hannan, M., Zeng, F., Xu, S. Z., Khan, S. U., Levenson, R., Beech, D. J., Weiss, J. L.

J Physiol

2006

16461353

Regulation of the transient receptor potential channel TRPM2 by the Ca2+ sensor calmodulin.

Tong, Q., Zhang, W., Conrad, K., Mostoller, K., Cheung, J. Y., Peterson, B. Z., Miller, B. A.

J Biol Chem

2006

16418302

Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells.

Sours, S., Du, J., Chu, S., Ding, M., Zhou, X. J., Ma, R.

Am J Physiol Renal Physiol

2006

16407977

TRPM7, a novel regulator of actomyosin contractility and cell adhesion.

Clark, K., Langeslag, M., van Leeuwen, B., Ran, L., Ryazanov, A. G., Figdor, C. G., Moolenaar, W. H., Jalink, K., van Leeuwen, F. N.

EMBO J

2006

16407161

Role of Src in C3 transient receptor potential channel function and evidence for a heterogeneous makeup of receptor- and store-operated Ca2+ entry channels.

Kawasaki, B. T., Liao, Y., Birnbaumer, L.

Proc Natl Acad Sci U S A

2006

16380433

Identification of BSPRY as a novel auxiliary protein inhibiting TRPV5 activity.

van de Graaf, S. F., van der Kemp, A. W., van den Berg, D., van Oorschot, M., Hoenderop, J. G., Bindels, R. J.

J Am Soc Nephrol

2006

16354700

Direct interaction with Rab11a targets the epithelial Ca2+ channels TRPV5 and TRPV6 to the plasma membrane.

van de Graaf, S. F., Chang, Q., Mensenkamp, A. R., Hoenderop, J. G., Bindels, R. J.

Mol Cell Biol

2006

16352746

The immunophilin FKBP52 inhibits the activity of the epithelial Ca2+ channel TRPV5.

Gkika, D., Topala, C. N., Hoenderop, J. G., Bindels, R. J.

Am J Physiol Renal Physiol

2006

16319926

NGF rapidly increases membrane expression of TRPV1 heat-gated ion channels.

Zhang, X., Huang, J., McNaughton, P. A.

EMBO J

2005

16311606

Polycystin-1 and polycystin-2 regulate the cell cycle through the helix-loop-helix inhibitor Id2.

Li, X., Luo, Y., Starremans, P. G., McNamara, C. A., Pei, Y., Zhou, J.

Nat Cell Biol

2005

16270640

Transient receptor potential protein subunit assembly and membrane distribution in human platelets.

Brownlow, S. L., Sage, S. O.

Thromb Haemost

2005

16254212

Activation of the endothelial store-operated ISOC Ca2+ channel requires interaction of protein 4.1 with TRPC4.

Cioffi, D. L., Wu, S., Alexeyev, M., Goodman, S. R., Zhu, M. X., Stevens, T.

Circ Res

2005

16239475

The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel.

Chang, Q., Hoefs, S., van der Kemp, A. W., Topala, C. N., Bindels, R. J., Hoenderop, J. G.

Science

2005

16237318

Heteromerization and colocalization of TrpV1 and TrpV2 in mammalian cell lines and rat dorsal root ganglia.

Rutter, A. R., Ma, Q. P., Leveridge, M., Bonnert, T. P.

Neuroreport

2005

16223735

Polycystin 2 interacts with type I inositol 1,4,5-trisphosphate receptor to modulate intracellular Ca2+ signaling.

Li, Y., Wright, J. M., Qian, F., Germino, G. G., Guggino, W. B.

J Biol Chem

2005

16189514

Towards a proteome-scale map of the human protein-protein interaction network.

Rual, J. F., Venkatesan, K., Hao, T., Hirozane-Kishikawa, T., Dricot, A., Li, N., Berriz, G. F., Gibbons, F. D., Dreze, M., Ayivi-Guedehoussou, N., Klitgord, N., Simon, C., Boxem, M., Milstein, S., Rosenberg, J., Goldberg, D. S., Zhang, L. V., Wong, S. L., Franklin, G., Li, S., Albala, J. S., Lim, J., Fraughton, C., Llamosas, E., Cevik, S., Bex, C., Lamesch, P., Sikorski, R. S., Vandenhaute, J., Zoghbi, H. Y., Smolyar, A., Bosak, S., Sequerra, R., Doucette-Stamm, L., Cusick, M. E., Hill, D. E., Roth, F. P., Vidal, M.

Nature

2005

16169070

A human protein-protein interaction network: a resource for annotating the proteome.

Stelzl, U., Worm, U., Lalowski, M., Haenig, C., Brembeck, F. H., Goehler, H., Stroedicke, M., Zenkner, M., Schoenherr, A., Koeppen, S., Timm, J., Mintzlaff, S., Abraham, C., Bock, N., Kietzmann, S., Goedde, A., Toksoz, E., Droege, A., Krobitsch, S., Korn, B., Birchmeier, W., Lehrach, H., Wanker, E. E.

Cell

2005

16153633

Junctate, an inositol 1,4,5-triphosphate receptor associated protein, is present in rodent sperm and binds TRPC2 and TRPC5 but not TRPC1 channels.

Stamboulian, S., Moutin, M. J., Treves, S., Pochon, N., Grunwald, D., Zorzato, F., De Waard, M., Ronjat, M., Arnoult, C.

Dev Biol

2005

16144838

Epidermal growth factor induces tyrosine phosphorylation, membrane insertion, and activation of transient receptor potential channel 4.

Odell, A. F., Scott, J. L., Van Helden, D. F.

J Biol Chem

2005

16135816

PKD2 functions as an epidermal growth factor-activated plasma membrane channel.

Ma, R., Li, W. P., Rundle, D., Kong, J., Akbarali, H. I., Tsiokas, L.

Mol Cell Biol

2005

16115206

Extensive co-localization and heteromultimer formation of the vanilloid receptor-like protein TRPV2 and the capsaicin receptor TRPV1 in the adult rat cerebral cortex.

Liapi, A., Wood, J. N.

Eur J Neurosci

2005

16025302

Proteomic analysis of TRPC5- and TRPC6-binding partners reveals interaction with the plasmalemmal Na(+)/K(+)-ATPase.

Goel, M., Sinkins, W., Keightley, A., Kinter, M., Schilling, W. P.

Pflugers Arch

2005

15994335

Activation of M1 muscarinic acetylcholine receptors stimulates the formation of a multiprotein complex centered on TRPC6 channels.

Kim, J. Y., Saffen, D.

J Biol Chem

2005

15987684

Calmodulin and calcium interplay in the modulation of TRPC5 channel activity. Identification of a novel C-terminal domain for calcium/calmodulin-mediated facilitation.

Ordaz, B., Tang, J., Xiao, R., Salgado, A., Sampieri, A., Zhu, M. X., Vaca, L.

J Biol Chem

2005

15972814

Endogenous TRPC1, TRPC3, and TRPC7 proteins combine to form native store-operated channels in HEK-293 cells.

Zagranichnaya, T. K., Wu, X., Villereal, M. L.

J Biol Chem

2005

15935109

Plasma membrane localization and function of TRPC1 is dependent on its interaction with beta-tubulin in retinal epithelium cells.

Bollimuntha, S., Cornatzer, E., Singh, B. B.

Vis Neurosci

2005

15924139

TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function.

Reiser, J., Polu, K. R., Moller, C. C., Kenlan, P., Altintas, M. M., Wei, C., Faul, C., Herbert, S., Villegas, I., Avila-Casado, C., McGee, M., Sugimoto, H., Brown, D., Kalluri, R., Mundel, P., Smith, P. L., Clapham, D. E., Pollak, M. R.

Nat Genet

2005

15895247

Inhibition of TRPC5 channels by Ca2+-binding protein 1 in Xenopus oocytes.

Kinoshita-Kawada, M., Tang, J., Xiao, R., Kaneko, S., Foskett, J. K., Zhu, M. X.

Pflugers Arch

2005

15894168

Tyrosine phosphatase PTP1B interacts with TRPV6 in vivo and plays a role in TRPV6-mediated calcium influx in HEK293 cells.

Sternfeld, L., Krause, E., Schmid, A., Anderie, I., Latas, A., Al-Shaldi, H., Kohl, A., Evers, K., Hofer, H. W., Schulz, I.

Cell Signal

2005

15883036

Identification of a protein that interacts with the vanilloid receptor.

Lee, S. Y.

Biochem Biophys Res Commun

2005

15843396

Alpha-actinin associates with polycystin-2 and regulates its channel activity.

Li, Q., Montalbetti, N., Shen, P. Y., Dai, X. Q., Cheeseman, C. I., Karpinski, E., Wu, G., Cantiello, H. F., Chen, X. Z.

Hum Mol Genet

2005

15834157

Molecular analysis of a store-operated and 2-acetyl-sn-glycerol-sensitive non-selective cation channel. Heteromeric assembly of TRPC1-TRPC3.

Liu, X., Bandyopadhyay, B. C., Singh, B. B., Groschner, K., Ambudkar, I. S.

J Biol Chem

2005

15758179

Canonical transient receptor potential 1 plays a role in basic fibroblast growth factor (bFGF)/FGF receptor-1-induced Ca2+ entry and embryonic rat neural stem cell proliferation.

Fiorio Pla, A., Maric, D., Brazer, S. C., Giacobini, P., Liu, X., Chang, Y. H., Ambudkar, I. S., Barker, J. L.

J Neurosci

2005

15757897

MxA, a member of the dynamin superfamily, interacts with the ankyrin-like repeat domain of TRPC.

Lussier, M. P., Cayouette, S., Lepage, P. K., Bernier, C. L., Francoeur, N., St-Hilaire, M., Pinard, M., Boulay, G.

J Biol Chem

2005

15744307

Phospholipase Cgamma1 controls surface expression of TRPC3 through an intermolecular PH domain.

van Rossum, D. B., Patterson, R. L., Sharma, S., Barrow, R. K., Kornberg, M., Gill, D. L., Snyder, S. H.

Nature

2005

15713749

Homo- and heteromeric assembly of TRPV channel subunits.

Hellwig, N., Albrecht, N., Harteneck, C., Schultz, G., Schaefer, M.

J Cell Sci

2005

15692563

Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation.

Kottgen, M., Benzing, T., Simmen, T., Tauber, R., Buchholz, B., Feliciangeli, S., Huber, T. B., Schermer, B., Kramer-Zucker, A., Hopker, K., Simmen, K. C., Tschucke, C. C., Sandford, R., Kim, E., Thomas, G., Walz, G.

EMBO J

2005

15665527

Requirement of PDZ domains for the stimulation of the epithelial Ca2+ channel TRPV5 by the NHE regulating factor NHERF2 and the serum and glucocorticoid inducible kinase SGK1.

Palmada, M., Poppendieck, S., Embark, H. M., van de Graaf, S. F., Boehmer, C., Bindels, R. J., Lang, F.

Cell Physiol Biochem

2005

15654973

Phospholipase cgamma1 is required for activation of store-operated channels in human keratinocytes.

Tu, C. L., Chang, W., Bikle, D. D.

J Invest Dermatol

2005

15623527

Apical localization of a functional TRPC3/TRPC6-Ca2+-signaling complex in polarized epithelial cells. Role in apical Ca2+ influx.

Bandyopadhyay, B. C., Swaim, W. D., Liu, X., Redman, R. S., Patterson, R. L., Ambudkar, I. S.

J Biol Chem

2005

15590898

Expression of TRPC4 channel protein that interacts with NHERF-2 in rat descending vasa recta.

Lee-Kwon, W., Wade, J. B., Zhang, Z., Pallone, T. L., Weinman, E. J.

Am J Physiol Cell Physiol

2005

15590641

Regulation of the Ca2+ sensitivity of the nonselective cation channel TRPM4.

Nilius, B., Prenen, J., Tang, J., Wang, C., Owsianik, G., Janssens, A., Voets, T., Zhu, M. X.

J Biol Chem

2005

15569253

Identification and characterization of a Ca2+ -sensitive interaction of the vanilloid receptor TRPV1 with tubulin.

Goswami, C., Dreger, M., Jahnel, R., Bogen, O., Gillen, C., Hucho, F.

J Neurochem

2004

15548533

Genomic organization and functional analysis of murine PKD2L1.

Murakami, M., Ohba, T., Xu, F., Shida, S., Satoh, E., Ono, K., Miyoshi, I., Watanabe, H., Ito, H., Iijima, T.

J Biol Chem

2005

15547947

Formation of a physiological complex between TRPV2 and RGA protein promotes cell surface expression of TRPV2.

Stokes, A. J., Wakano, C., Del Carmen, K. A., Koblan-Huberson, M., Turner, H.

J Cell Biochem

2005

15540229

Canonical transient receptor potential channel 4 (TRPC4) co-localizes with the scaffolding protein ZO-1 in human fetal astrocytes in culture.

Song, X., Zhao, Y., Narcisse, L., Duffy, H., Kress, Y., Lee, S., Brosnan, C. F.

Glia

2005

15537648

Orexin-A-induced Ca2+ entry: evidence for involvement of trpc channels and protein kinase C regulation.

Larsson, K. P., Peltonen, H. M., Bart, G., Louhivuori, L. M., Penttonen, A., Antikainen, M., Kukkonen, J. P., Akerman, K. E.

J Biol Chem

2005

15485879

Phosphorylation of annexin I by TRPM7 channel-kinase.

Dorovkov, M. V., Ryazanov, A. G.

J Biol Chem

2004

15471852

Interaction between protein kinase Cmu and the vanilloid receptor type 1.

Wang, Y., Kedei, N., Wang, M., Wang, Q. J., Huppler, A. R., Toth, A., Tran, R., Blumberg, P. M.

J Biol Chem

2004

15385169

Enkurin is a novel calmodulin and TRPC channel binding protein in sperm.

Sutton, K. A., Jungnickel, M. K., Wang, Y., Cullen, K., Lambert, S., Florman, H. M.

Dev Biol

2004

15337773

Pericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assembly.

Jurczyk, A., Gromley, A., Redick, S., San Agustin, J., Witman, G., Pazour, G. J., Peters, D. J., Doxsey, S.

J Cell Biol

2004

15329338

Erythropoietin-modulated calcium influx through TRPC2 is mediated by phospholipase Cgamma and IP3R.

Tong, Q., Chu, X., Cheung, J. Y., Conrad, K., Stahl, R., Barber, D. L., Mignery, G., Miller, B. A.

Am J Physiol Cell Physiol

2004

15327778

VAMP2-dependent exocytosis regulates plasma membrane insertion of TRPC3 channels and contributes to agonist-stimulated Ca2+ influx.

Singh, B. B., Lockwich, T. P., Bandyopadhyay, B. C., Liu, X., Bollimuntha, S., Brazer, S. C., Combs, C., Das, S., Leenders, A. G., Sheng, Z. H., Knepper, M. A., Ambudkar, S. V., Ambudkar, I. S.

Mol Cell

2004

15302852

Junctate is a key element in calcium entry induced by activation of InsP3 receptors and/or calcium store depletion.

Treves, S., Franzini-Armstrong, C., Moccagatta, L., Arnoult, C., Grasso, C., Schrum, A., Ducreux, S., Zhu, M. X., Mikoshiba, K., Girard, T., Smida-Rezgui, S., Ronjat, M., Zorzato, F.

J Cell Biol

2004

15249591

A TRPV2-PKA signaling module for transduction of physical stimuli in mast cells.

Stokes, A. J., Shimoda, L. M., Koblan-Huberson, M., Adra, C. N., Turner, H.

J Exp Med

2004

15199065

Association of immunophilins with mammalian TRPC channels.

Sinkins, W. G., Goel, M., Estacion, M., Schilling, W. P.

J Biol Chem

2004

15194699

PIGEA-14, a novel coiled-coil protein affecting the intracellular distribution of polycystin-2.

Hidaka, S., Konecke, V., Osten, L., Witzgall, R.

J Biol Chem

2004

15188402

Proteins associated with type II bone morphogenetic protein receptor (BMPR-II) and identified by two-dimensional gel electrophoresis and mass spectrometry.

Hassel, S., Eichner, A., Yakymovych, M., Hellman, U., Knaus, P., Souchelnytskyi, S.

Proteomics

2004

15123714

PKD2 interacts and co-localizes with mDia1 to mitotic spindles of dividing cells: role of mDia1 IN PKD2 localization to mitotic spindles.

Rundle, D. R., Gorbsky, G., Tsiokas, L.

J Biol Chem

2004

15123711

Regulation of the mouse epithelial Ca2(+) channel TRPV6 by the Ca(2+)-sensor calmodulin.

Lambers, T. T., Weidema, A. F., Nilius, B., Hoenderop, J. G., Bindels, R. J.

J Biol Chem

2004

15121806

A role for SNAP-25 but not VAMPs in store-mediated Ca2+ entry in human platelets.

Redondo, P. C., Harper, A. G., Salido, G. M., Pariente, J. A., Sage, S. O., Rosado, J. A.

J Physiol

2004

15104175

TRPC channel interactions with calmodulin and IP3 receptors.

Zhu, M. X., Tang, J.

Novartis Found Symp

2004

15100231

80K-H as a new Ca2+ sensor regulating the activity of the epithelial Ca2+ channel transient receptor potential cation channel V5 (TRPV5).

Gkika, D., Mahieu, F., Nilius, B., Hoenderop, J. G., Bindels, R. J.

J Biol Chem

2004

15084474

Modulation of TRPV1 by nonreceptor tyrosine kinase, c-Src kinase.

Jin, X., Morsy, N., Winston, J., Pasricha, P. J., Garrett, K., Akbarali, H. I.

Am J Physiol Cell Physiol

2004

15066994

Regulated exocytosis contributes to protein kinase C potentiation of vanilloid receptor activity.

Morenilla-Palao, C., Planells-Cases, R., Garcia-Sanz, N., Ferrer-Montiel, A.

J Biol Chem

2004

15060061

The N-terminal extracellular domain is required for polycystin-1-dependent channel activity.

Babich, V., Zeng, W. Z., Yeh, B. I., Ibraghimov-Beskrovnaya, O., Cai, Y., Somlo, S., Huang, C. L.

J Biol Chem

2004

14991772

RGA protein associates with a TRPV ion channel during biosynthesis and trafficking.

Barnhill, J. C., Stokes, A. J., Koblan-Huberson, M., Shimoda, L. M., Muraguchi, A., Adra, C. N., Turner, H.

J Cell Biochem

2004

14983059

Regulation of canonical transient receptor potential isoform 3 (TRPC3) channel by protein kinase G.

Kwan, H. Y., Huang, Y., Yao, X.

Proc Natl Acad Sci U S A

2004

14976260

Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia.

Chubanov, V., Waldegger, S., Mederos y Schnitzler, M., Vitzthum, H., Sassen, M. C., Seyberth, H. W., Konrad, M., Gudermann, T.

Proc Natl Acad Sci U S A

2004

14761972

Regulation of TRPC6 channel activity by tyrosine phosphorylation.

Hisatsune, C., Kuroda, Y., Nakamura, K., Inoue, T., Nakamura, T., Michikawa, T., Mizutani, A., Mikoshiba, K.

J Biol Chem

2004

14736881

Ca(2+) signaling by TRPC3 involves Na(+) entry and local coupling to the Na(+)/Ca(2+) exchanger.

Rosker, C., Graziani, A., Lukas, M., Eder, P., Zhu, M. X., Romanin, C., Groschner, K.

J Biol Chem

2004

14699131

Interaction of TRPC2 and TRPC6 in erythropoietin modulation of calcium influx.

Chu, X., Tong, Q., Cheung, J. Y., Wozney, J., Conrad, K., Mazack, V., Zhang, W., Stahl, R., Barber, D. L., Miller, B. A.

J Biol Chem

2004

14699077

Ca2+/calmodulin modulates TRPV1 activation by capsaicin.

Rosenbaum, T., Gordon-Shaag, A., Munari, M., Gordon, S. E.

J Gen Physiol

2004

14614461

Activation of the TRPC1 cation channel by metabotropic glutamate receptor mGluR1.

Kim, S. J., Kim, Y. S., Yuan, J. P., Petralia, R. S., Worley, P. F., Linden, D. J.

Nature

2003

14551243

Cholesterol depletion impairs vascular reactivity to endothelin-1 by reducing store-operated Ca2+ entry dependent on TRPC1.

Bergdahl, A., Gomez, M. F., Dreja, K., Xu, S. Z., Adner, M., Beech, D. J., Broman, J., Hellstrand, P., Sward, K.

Circ Res

2003

14530267

Inhibitor of myogenic family, a novel suppressor of store-operated currents through an interaction with TRPC1.

Ma, R., Rundle, D., Jacks, J., Koch, M., Downs, T., Tsiokas, L.

J Biol Chem

2003

14523239

Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1).

Bhave, G., Hu, H. J., Glauner, K. S., Zhu, W., Wang, H., Brasier, D. J., Oxford, G. S., Gereau, R. W. 4th

Proc Natl Acad Sci U S A

2003

14517216

Microtubule-associated [corrected] protein 7 increases the membrane expression of transient receptor potential vanilloid 4 (TRPV4).

Suzuki, M., Hirao, A., Mizuno, A.

J Biol Chem

2003

14505576

Homer binds TRPC family channels and is required for gating of TRPC1 by IP3 receptors.

Yuan, J. P., Kiselyov, K., Shin, D. M., Chen, J., Shcheynikov, N., Kang, S. H., Dehoff, M. H., Schwarz, M. K., Seeburg, P. H., Muallem, S., Worley, P. F.

Cell

2003

12970180

Amplification of receptor signalling by Ca2+ entry-mediated translocation and activation of PLCgamma2 in B lymphocytes.

Nishida, M., Sugimoto, K., Hara, Y., Mori, E., Morii, T., Kurosaki, T., Mori, Y.

EMBO J

2003

12937304

Analysis of the polycystins in aortic vascular smooth muscle cells.

Qian, Q., Li, M., Cai, Y., Ward, C. J., Somlo, S., Harris, P. C., Torres, V. E.

J Am Soc Nephrol

2003

12858178

TRPC5 is a regulator of hippocampal neurite length and growth cone morphology.

Greka, A., Navarro, B., Oancea, E., Duggan, A., Clapham, D. E.

Nat Neurosci

2003

12857742

Formation of novel TRPC channels by complex subunit interactions in embryonic brain.

Strubing, C., Krapivinsky, G., Krapivinsky, L., Clapham, D. E.

J Biol Chem

2003

12840011

Polycystin-1 distribution is modulated by polycystin-2 expression in mammalian cells.

Grimm, D. H., Cai, Y., Chauvet, V., Rajendran, V., Zeltner, R., Geng, L., Avner, E. D., Sweeney, W., Somlo, S., Caplan, M. J.

J Biol Chem

2003

12809519

Troponin I binds polycystin-L and inhibits its calcium-induced channel activation.

Li, Q., Liu, Y., Shen, P. Y., Dai, X. Q., Wang, S., Smillie, L. B., Sandford, R., Chen, X. Z.

Biochemistry

2003

12808128

Structural determinant of TRPV1 desensitization interacts with calmodulin.

Numazaki, M., Tominaga, T., Takeuchi, K., Murayama, N., Toyooka, H., Tominaga, M.

Proc Natl Acad Sci U S A

2003

12766172

RhoA interaction with inositol 1,4,5-trisphosphate receptor and transient receptor potential channel-1 regulates Ca2+ entry. Role in signaling increased endothelial permeability.

Mehta, D., Ahmmed, G. U., Paria, B. C., Holinstat, M., Voyno-Yasenetskaya, T., Tiruppathi, C., Minshall, R. D., Malik, A. B.

J Biol Chem

2003

12765696

The TRPV6 gene, cDNA and protein.

Hirnet, D., Olausson, J., Fecher-Trost, C., Bodding, M., Nastainczyk, W., Wissenbach, U., Flockerzi, V., Freichel, M.

Cell Calcium

2003

12732636

Caveolin-1 contributes to assembly of store-operated Ca2+ influx channels by regulating plasma membrane localization of TRPC1.

Brazer, S. C., Singh, B. B., Liu, X., Swaim, W., Ambudkar, I. S.

J Biol Chem

2003

12724311

Ca2+-dependent potentiation of the nonselective cation channel TRPV4 is mediated by a C-terminal calmodulin binding site.

Strotmann, R., Schultz, G., Plant, T. D.

J Biol Chem

2003

12660155

Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex.

van de Graaf, S. F., Hoenderop, J. G., Gkika, D., Lamers, D., Prenen, J., Rescher, U., Gerke, V., Staub, O., Nilius, B., Bindels, R. J.

EMBO J

2003

12601176

The mouse C-type transient receptor potential 2 (TRPC2) channel: alternative splicing and calmodulin binding to its N terminus.

Yildirim, E., Dietrich, A., Birnbaumer, L.

Proc Natl Acad Sci U S A

2003

12574114

Homo- and heterotetrameric architecture of the epithelial Ca2+ channels TRPV5 and TRPV6.

Hoenderop, J. G., Voets, T., Hoefs, S., Weidema, F., Prenen, J., Nilius, B., Bindels, R. J.

EMBO J

2003

12538589

Regulation of a transient receptor potential (TRP) channel by tyrosine phosphorylation. SRC family kinase-dependent tyrosine phosphorylation of TRPV4 on TYR-253 mediates its response to hypotonic stress.

Xu, H., Zhao, H., Tian, W., Yoshida, K., Roullet, J. B., Cohen, D. M.

J Biol Chem

2003

12527301

Polycystin-2 associates with tropomyosin-1, an actin microfilament component.

Li, Q., Dai, Y., Guo, L., Liu, Y., Hao, C., Wu, G., Basora, N., Michalak, M., Chen, X. Z.

J Mol Biol

2003

12525172

Polycystin-2 interacts with troponin I, an angiogenesis inhibitor.

Li, Q., Shen, P. Y., Wu, G., Chen, X. Z.

Biochemistry

2003

12472899

Type-specific inositol 1,4,5-trisphosphate receptor localization in the vomeronasal organ and its interaction with a transient receptor potential channel, TRPC2.

Brann, J. H., Dennis, J. C., Morrison, E. E., Fadool, D. A.

J Neurochem

2002

12437926

Phospholipase C-gamma is required for agonist-induced Ca2+ entry.

Patterson, R. L., van Rossum, D. B., Ford, D. L., Hurt, K. J., Bae, S. S., Suh, P. G., Kurosaki, T., Snyder, S. H., Gill, D. L.

Cell

2002

12379180

Ca(2+)-calmodulin regulates receptor-operated Ca(2+) entry activity of TRPC6 in HEK-293 cells.

Boulay, G.

Cell Calcium

2002

12377790

Selective association of TRPC channel subunits in rat brain synaptosomes.

Goel, M., Sinkins, W. G., Schilling, W. P.

J Biol Chem

2002

12196544

Endogenously expressed Trp1 is involved in store-mediated Ca2+ entry by conformational coupling in human platelets.

Rosado, J. A., Brownlow, S. L., Sage, S. O.

J Biol Chem

2002

12194871

cAMP-dependent protein kinase regulates desensitization of the capsaicin receptor (VR1) by direct phosphorylation.

Bhave, G., Zhu, W., Wang, H., Brasier, D. J., Oxford, G. S., Gereau, R. W. 4th

Neuron

2002

12167663

Erythropoietin modulates calcium influx through TRPC2.

Chu, X., Cheung, J. Y., Barber, D. L., Birnbaumer, L., Rothblum, L. I., Conrad, K., Abrasonis, V., Chan, Y. M., Stahl, R., Carey, D. J., Miller, B. A.

J Biol Chem

2002

12154080

The PDZ-interacting domain of TRPC4 controls its localization and surface expression in HEK293 cells.

Mery, L., Strauss, B., Dufour, J. F., Krause, K. H., Hoth, M.

J Cell Sci

2002

12077606

TRPV3 is a temperature-sensitive vanilloid receptor-like protein.

Smith, G. D., Gunthorpe, M. J., Kelsell, R. E., Hayes, P. D., Reilly, P., Facer, P., Wright, J. E., Jerman, J. C., Walhin, J. P., Ooi, L., Egerton, J., Charles, K. J., Smart, D., Randall, A. D., Anand, P., Davis, J. B.

Nature

2002

12032305

Subunit composition of mammalian transient receptor potential channels in living cells.

Hofmann, T., Schaefer, M., Schultz, G., Gudermann, T.

Proc Natl Acad Sci U S A

2002

11983166

Calmodulin regulates Ca(2+)-dependent feedback inhibition of store-operated Ca(2+) influx by interaction with a site in the C terminus of TrpC1.

Singh, B. B., Liu, X., Tang, J., Zhu, M. X., Ambudkar, I. S.

Mol Cell

2002

11941371

The TRPM7 channel is inactivated by PIP(2) hydrolysis.

Runnels, L. W., Yue, L., Clapham, D. E.

Nat Cell Biol

2002

11901144

Identification, characterization, and localization of a novel kidney polycystin-1-polycystin-2 complex.

Newby, L. J., Streets, A. J., Zhao, Y., Harris, P. C., Ward, C. J., Ong, A. C.

J Biol Chem

2002

11884385

Direct phosphorylation of capsaicin receptor VR1 by protein kinase Cepsilon and identification of two target serine residues.

Numazaki, M., Tominaga, T., Toyooka, H., Tominaga, M.

J Biol Chem

2002

11524429

Stabilization of cortical actin induces internalization of transient receptor potential 3 (Trp3)-associated caveolar Ca2+ signaling complex and loss of Ca2+ influx without disruption of Trp3-inositol trisphosphate receptor association.

Lockwich, T., Singh, B. B., Liu, X., Ambudkar, I. S.

J Biol Chem

2001

11418861

Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition.

Chuang, H. H., Prescott, E. D., Kong, H., Shields, S., Jordt, S. E., Basbaum, A. I., Chao, M. V., Julius, D.

Nature

2001

11336651

Activation of store-mediated calcium entry by secretion-like coupling between the inositol 1,4,5-trisphosphate receptor type II and human transient receptor potential (hTrp1) channels in human platelets.

Rosado, J. A., Sage, S. O.

Biochem J

2001

11311128

The transient receptor potential, TRP4, cation channel is a novel member of the family of calmodulin binding proteins.

Trost, C., Bergs, C., Himmerkus, N., Flockerzi, V.

Biochem J

2001

11301024

TRPC1 and TRPC5 form a novel cation channel in mammalian brain.

Strubing, C., Krapivinsky, G., Krapivinsky, L., Clapham, D. E.

Neuron

2001

11290752

Identification of common binding sites for calmodulin and inositol 1,4,5-trisphosphate receptors on the carboxyl termini of trp channels.

Tang, J., Lin, Y., Zhang, Z., Tikunova, S., Birnbaumer, L., Zhu, M. X.

J Biol Chem

2001

11248124

Competitive regulation of CaT-like-mediated Ca2+ entry by protein kinase C and calmodulin.

Niemeyer, B. A., Bergs, C., Wissenbach, U., Flockerzi, V., Trost, C.

Proc Natl Acad Sci U S A

2001

11248050

Activation of Trp3 by inositol 1,4,5-trisphosphate receptors through displacement of inhibitory calmodulin from a common binding domain.

Zhang, Z., Tang, J., Tikunova, S., Johnson, J. D., Chen, Z., Qin, N., Dietrich, A., Stefani, E., Birnbaumer, L., Zhu, M. X.

Proc Natl Acad Sci U S A

2001

11163362

Alternative splice variants of hTrp4 differentially interact with the C-terminal portion of the inositol 1,4,5-trisphosphate receptors.

Mery, L., Magnino, F., Schmidt, K., Krause, K. H., Dufour, J. F.

FEBS Lett

2001

11161216

TRP-PLIK, a bifunctional protein with kinase and ion channel activities.

Runnels, L. W., Yue, L., Clapham, D. E.

Science

2001

11140688

Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents.

Hanaoka, K., Qian, F., Boletta, A., Bhunia, A. K., Piontek, K., Tsiokas, L., Sukhatme, V. P., Guggino, W. B., Germino, G. G.

Nature

2000

10983988

Gating of store-operated channels by conformational coupling to ryanodine receptors.

Kiselyov, K. I., Shin, D. M., Wang, Y., Pessah, I. N., Allen, P. D., Muallem, S.

Mol Cell

2000

10980202

Association of mammalian trp4 and phospholipase C isozymes with a PDZ domain-containing protein, NHERF.

Tang, Y., Tang, J., Chen, Z., Trost, C., Flockerzi, V., Li, M., Ramesh, V., Zhu, M. X.

J Biol Chem

2000

10980191

Expression of truncated transient receptor potential protein 1alpha (Trp1alpha ): evidence that the Trp1 C terminus modulates store-operated Ca2+ entry.

Singh, B. B., Liu, X., Ambudkar, I. S.

J Biol Chem

2000

10970773

Coupling between inositol 1,4,5-trisphosphate receptors and human transient receptor potential channel 1 when intracellular Ca2+ stores are depleted.

Rosado, J. A., Sage, S. O.

Biochem J

2000

10913159

In vivo interaction of the adapter protein CD2-associated protein with the type 2 polycystic kidney disease protein, polycystin-2.

Lehtonen, S., Ora, A., Olkkonen, V. M., Geng, L., Zerial, M., Somlo, S., Lehtonen, E.

J Biol Chem

2000

10882720

Coassembly of Trp1 and Trp3 proteins generates diacylglycerol- and Ca2+-sensitive cation channels.

Lintschinger, B., Balzer-Geldsetzer, M., Baskaran, T., Graier, W. F., Romanin, C., Zhu, M. X., Groschner, K.

J Biol Chem

2000

10766822

Assembly of Trp1 in a signaling complex associated with caveolin-scaffolding lipid raft domains.

Lockwich, T. P., Liu, X., Singh, B. B., Jadlowiec, J., Weiland, S., Ambudkar, I. S.

J Biol Chem

2000

10760273

The polycystic kidney disease protein PKD2 interacts with Hax-1, a protein associated with the actin cytoskeleton.

Gallagher, A. R., Cedzich, A., Gretz, N., Somlo, S., Witzgall, R.

Proc Natl Acad Sci U S A

2000

10677043

Activation of a TRPC3-dependent cation current through the neurotrophin BDNF.

Li, H. S., Xu, X. Z., Montell, C.

Neuron

1999

10611319

Modulation of Ca(2+) entry by polypeptides of the inositol 1,4, 5-trisphosphate receptor (IP3R) that bind transient receptor potential (TRP): evidence for roles of TRP and IP3R in store depletion-activated Ca(2+) entry.

Boulay, G., Brown, D. M., Qin, N., Jiang, M., Dietrich, A., Zhu, M. X., Chen, Z., Birnbaumer, M., Mikoshiba, K., Birnbaumer, L.

Proc Natl Acad Sci U S A

1999

10518223

The N-terminal domain of the IP3 receptor gates store-operated hTrp3 channels.

Kiselyov, K., Mignery, G. A., Zhu, M. X., Muallem, S.

Mol Cell

1999

10097141

Specific association of the gene product of PKD2 with the TRPC1 channel.

Tsiokas, L., Arnould, T., Zhu, C., Kim, E., Walz, G., Sukhatme, V. P.

Proc Natl Acad Sci U S A

1999

9215637

Coassembly of TRP and TRPL produces a distinct store-operated conductance.

Xu, X. Z., Li, H. S., Guggino, W. B., Montell, C.

Cell

1997

9192675

Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2.

Tsiokas, L., Kim, E., Arnould, T., Sukhatme, V. P., Walz, G.

Proc Natl Acad Sci U S A

1997

9171830

PKD1 interacts with PKD2 through a probable coiled-coil domain.

Qian, F., Germino, F. J., Cai, Y., Zhang, X., Somlo, S., Germino, G. G.

Nat Genet

1997