Statistics

TRIP Database documents 711 PPI pairs among 28 TRP channels and 440 cellular proteins by curating 426 peer-reviewed publications.

Number of curated publications

1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 Total
3 0 4 9 10 14 23 27 38 34 26 49 33 31 26 41 31 27 426

Number of PPI pairs

TRPC
TRP
channel
# of
PPI pairs
TRPC1 56
TRPC2 13
TRPC3 118
TRPC4 39
TRPC5 59
TRPC6 46
TRPC7 12
   
Total 343
TRPV
TRP
channel
# of
PPI pairs
TRPV1 93
TRPV2 9
TRPV3 4
TRPV4 38
TRPV5 17
TRPV6 20
   
   
Total 181
TRPM
TRP
channel
# of
PPI pairs
TRPM1 3
TRPM2 5
TRPM3 4
TRPM4 7
TRPM5 0
TRPM6 7
TRPM7 15
TRPM8 5
Total 46
TRPML
TRP
channel
# of
PPI pairs
TRPML1 33
TRPML2 3
TRPML3 8
   
   
   
   
   
Total 44
TRPP
TRP
channel
# of
PPI pairs
TRPP1 116
TRPP2 8
TRPP3 1
   
   
   
   
   
Total 125
TRPA
TRP
channel
# of
PPI pairs
TRPA1 8
   
   
   
   
   
   
   
Total 8

Comparison of experimentally verified PPI databases

Number of PPI pairs

  TRPC1 TRPC2 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TRPV1 TRPV2 TRPV3 TRPV4 TRPV5 TRPV6
TRIP 56 13 118 39 59 46 12 93 9 4 38 17 20
DIP Question 3 0 1 0 0 0 0 0 0 0 0 1 0
IntAct Question 39 0 3 1 1 2 1 1 0 1 6 2 0
MINT Question 0 0 0 2 1 0 0 1 0 0 3 2 3
BioGRID Question 14 5 8 10 16 11 4 5 1 0 14 3 4
  TRPM1 TRPM2 TRPM3 TRPM4 TRPM5 TRPM6 TRPM7 TRPM8 TRPML1 TRPML2 TRPML3 TRPP1 TRPP2 TRPP3 TRPA1
TRIP 3 5 4 7 0 7 15 5 33 3 8 116 8 1 8
DIP Question 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
IntAct Question 0 0 0 0 0 0 0 0 2 0 1 0 0 0 0
MINT Question 0 0 0 0 0 3 4 0 2 0 0 4 1 0 0
BioGRID Question 1 1 0 1 0 0 8 0 2 0 1 8 2 0 2
TRP / Interactor

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