Statistics

TRIP Database documents 690 PPI pairs among 28 TRP channels and 425 cellular proteins by curating 396 peer-reviewed publications.

Number of curated publications

1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 Total
3 0 4 9 10 14 23 27 38 34 26 49 33 31 26 39 28 2 396

Number of PPI pairs

TRPC
TRP
channel
# of
PPI pairs
TRPC1 53
TRPC2 12
TRPC3 117
TRPC4 37
TRPC5 58
TRPC6 46
TRPC7 12
   
Total 335
TRPV
TRP
channel
# of
PPI pairs
TRPV1 89
TRPV2 9
TRPV3 4
TRPV4 37
TRPV5 17
TRPV6 19
   
   
Total 175
TRPM
TRP
channel
# of
PPI pairs
TRPM1 3
TRPM2 4
TRPM3 4
TRPM4 4
TRPM5 0
TRPM6 7
TRPM7 15
TRPM8 5
Total 42
TRPML
TRP
channel
# of
PPI pairs
TRPML1 32
TRPML2 3
TRPML3 7
   
   
   
   
   
Total 42
TRPP
TRP
channel
# of
PPI pairs
TRPP1 115
TRPP2 8
TRPP3 1
   
   
   
   
   
Total 124
TRPA
TRP
channel
# of
PPI pairs
TRPA1 8
   
   
   
   
   
   
   
Total 8

Comparison of experimentally verified PPI databases

Number of PPI pairs

  TRPC1 TRPC2 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TRPV1 TRPV2 TRPV3 TRPV4 TRPV5 TRPV6
TRIP 53 12 117 37 58 46 12 89 9 4 37 17 19
DIP Question 3 0 1 0 0 0 0 0 0 0 0 1 0
IntAct Question 39 0 3 1 1 2 1 1 0 1 6 2 0
MINT Question 0 0 0 2 1 0 0 1 0 0 3 2 3
BioGRID Question 14 5 8 10 16 11 4 5 1 0 14 3 4
  TRPM1 TRPM2 TRPM3 TRPM4 TRPM5 TRPM6 TRPM7 TRPM8 TRPML1 TRPML2 TRPML3 TRPP1 TRPP2 TRPP3 TRPA1
TRIP 3 4 4 4 0 7 15 5 32 3 7 115 8 1 8
DIP Question 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
IntAct Question 0 0 0 0 0 0 0 0 2 0 1 0 0 0 0
MINT Question 0 0 0 0 0 3 4 0 2 0 0 4 1 0 0
BioGRID Question 1 1 0 1 0 0 8 0 2 0 1 8 2 0 2
TRP / Interactor

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